Abstract: A device and a method for providing granular matter is described. The device includes a receiving container configured and adjusted for receiving the granular matter. The receiving container has an output for providing the granular matter to a further processing. The device has a measuring unit configured for measuring a density of the granular matter in the receiving container using terahertz spectroscopy.

Abstract: A method of monitoring a property of a dissolution of an at least partially solid dosage form during a dissolution process is disclosed. The method includes at least partially dissolving the dosage form, and during the dissolution of the dosage form, simultaneously monitoring the property of the dissolution of the dosage form in progress by low coherence interferometry.

Abstract: A method of monitoring a property of a dissolution of an at least partially solid dosage form during a dissolution process is disclosed. The method includes at least partially dissolving the dosage form, and during the dissolution of the dosage form, simultaneously monitoring the property of the dissolution of the dosage form in progress by low coherence interferometry.

Abstract: The present invention refers to a process to prepare a highly activated composite of one or more water-insoluble drugs, said process comprising the steps of: (a) subjecting said water-insoluble drug and a cross-linked polymer to co-grinding; (b) exposing the ground product of step a. to contact with water or water vapors. The resulting composite contains large amounts of drug in the easily soluble amorphous form, reduced amounts of drug in the nanocrystalline form, and is substantially free from practically insoluble drug crystals.

Abstract: A Medium Voltage Circuit Breaker (CB) comprising an electronic protection and control unit having: a base, fixed to the CB, comprising a main body having fixing means for fixing to the CB, a first side of said main body comprising a confined space including connections to the CB and internal accessories thereof, a second side of said main body comprising a plurality of first power and/or signal connection means; a removable unit comprising a casing, a first part of said casing hosting one or more Intelligent Electronic Devices, a second part of said casing being removably coupled to said base and comprising a plurality of second power and/or signal connection means connected to said first power and/or signal connection means.

Abstract: A single-coil actuator for low or medium voltage applications which comprises a first assembly which comprises a first casing having a first half-casing and a second half-casing coupled to each other. The first casing defines an internal space housing an electromagnet having a coil and an armature movable between two positions. The first half-casing has a first opening for the mechanical coupling of the armature with an external element, while one of the first or second half-casing has a second opening for the electrical connection of the electromagnet. The electrical connection comprises a first connection element of the socket and plug-type connection which is electrically connected to the coil and positioned in correspondence of the second opening.

Abstract: A Medium Voltage Circuit Breaker that has at least a pair of contact mutually coupleable and uncoupleable to carry out an opening/closing operation, a magnetic actuator operatively connected to at least one of the contacts, and a capacitor bank that has one or more capacitors that deliver power to the magnetic actuator for carrying out the opening/closing operation and a control device. The Medium Voltage Circuit Breaker further has a supervisor device of the capacitor bank which measures the Equivalent Series Resistance and/or the Capacitance of the capacitor bank system.

Abstract: A process is described for the activation (increase in solubility and bioavailability) of drugs. The process, carried out in a vibrational mill, is characterised by the use of given proportions between the physical mixture made up of drug and pharmaceutical carrier and the empty volume among the grinding means contained inside the mill. The process leads to obtaining powders for pharmaceutical use in which the drug has a high and constant degree of activation; this result is obtainable irrespective of the nature of the drug and carrier used, and of their weight ratio.

Abstract: A Medium Voltage Circuit Breaker (CB) comprising an electronic protection and control unit having: a base, fixed to the CB, comprising a main body having fixing means for fixing to the CB, a first side of said main body comprising a confined space including connections to the CB and internal accessories thereof, a second side of said main body comprising a plurality of first power and/or signal connection means; a removable unit comprising a casing, a first part of said casing hosting one or more Intelligent Electronic Devices, a second part of said casing being removably coupled to said base and comprising a plurality of second power and/or signal connection means connected to said first power and/or signal connection means.

Abstract: The invention comprises a process for activating drugs by means of high-energy co-grinding of the drug with a pharmaceutical carrier, characterized by the use of a vibrational mill equipped with means that regulate the vibration frequency. The process, performed by modifying the frequency of vibration and keeping its amplitude constant, produces drug/carrier composites with a constant particle size in which the degree of drug activation increases in proportion to the frequency applied. The invention also includes a vibrational mill suitably modified to perform the process described.

Abstract: A single-coil actuator for low or medium voltage applications which comprises a first assembly which comprises a first casing having a first half-casing and a second half-casing coupled to each other. The first casing defines an internal space housing an electromagnet having a coil and an armature movable between two positions. The first half-casing has a first opening for the mechanical coupling of the armature with an external element, while one of the first or second half-casing has a second opening for the electrical connection of the electromagnet. The electrical connection comprises a first connection element of the socket and plug-type connection which is electrically connected to the coil and positioned in correspondence of the second opening.

Abstract: A Medium Voltage Circuit Breaker that has at least a pair of contact mutually coupleable and uncoupleable to carry out an opening/closing operation, a magnetic actuator operatively connected to at least one of the contacts, and a capacitor bank that has one or more capacitors that deliver power to the magnetic actuator for carrying out the opening/closing operation and a control device. The Medium Voltage Circuit Breaker further has a supervisor device of the capacitor bank which measures the Equivalent Series Resistance and/or the Capacitance of the capacitor bank system.

Abstract: The invention comprises a process for activating drugs by means of high-energy co-grinding of the drug with a pharmaceutical carrier, characterised by the use of a vibrational mill equipped with means that regulate the vibration frequency. The process, performed by modifying the frequency of vibration and keeping its amplitude constant, produces drug/carrier composites with a constant particle size in which the degree of drug activation increases in proportion to the frequency applied. The invention also includes a vibrational mill suitably modified to perform the process described.

Abstract: The present invention refers to a process of loading drugs in a thermodynamic activated form into polymers by means of supercritical fluids. The process includes a pre-treatment step of the cross-linked polymer with pure supercritical fluid to allow a higher degree and a more rapid kinetic of drug loading into cross-linked polymers and also a higher thermodynamic activation of the drugs.

Abstract: The present invention refers to a process to prepare a highly activated composite of one or more water-insoluble drugs, said process comprising the steps of: (a) subjecting said water-insoluble drug and a cross-linked polymer to co-grinding; (b) exposing the ground product of step a. to contact with water or water vapours. The resulting composite contains large amounts of drug in the easily soluble amorphous form, reduced amounts of drug in the nanocrystalline form, and is substantially free from practically insoluble drug crystals.

Abstract: A process is described for the activation (increase in solubility and bioavailability) of drugs. The process, carried out in a vibrational mill, is characterised by the use of given proportions between the physical mixture made up of drug and pharmaceutical carrier and the empty volume among the grinding means contained inside the mill. The process leads to obtaining powders for pharmaceutical use in which the drug has a high and constant degree of activation; this result is obtainable irrespective of the nature of the drug and carrier used, and of their weight ratio.

Abstract: The invention comprises a process for activating drugs by means of high-energy co-grinding of the drug with a pharmaceutical carrier, characterised by the use of a vibrational mill equipped with means that regulate the vibration frequency. The process, performed by modifying the frequency of vibration and keeping its amplitude constant, produces drug/carrier composites with a constant particle size in which the degree of drug activation increases in proportion to the frequency applied. The invention also includes a vibrational mill suitably modified to perform the process described.

Abstract: A device for inhibiting the loading and use of portable guns such as rifles, pistols and the like for purposes of safety when a gun is transported or put away. The device comprises a dummy cartridge (11) to be inserted into the cartridge chamber of the barrel of a gun, a cable (12) which starts from the dummy cartridge, extends into the barrel for the entire length of same and ends with a final spacer (13) protruding from the muzzle end of the barrel, and a lock (14) applied to said spacer and resting directly or indirectly against the muzzle of the barrel.