Patents by Inventor Massimo Cini

Massimo Cini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-AMINO-4-PHENYL-4-OXO-BUTYRIC ACID DERIVATIVES
    Publication number: 20010008947
    Abstract: Use in the prevention and/or in the treatment of neurodegenerative diseases of 2-amino-4-phenyl-4-oxo-butyric acid derivatives which act as kynureninase enzyme inhibitors and/or kynurenine-3-hydroxylase enzyme inhibitors.
    Type: Application
    Filed: October 14, 1997
    Publication date: July 19, 2001
    Inventors: MARIO VARASI, ANTONIO GIORDANI, CARMELA SPECIALE, MASSIMO CINI, ALBERTO BIANCHETTI
  • N-substituted-2-amino-4-phenyl-4-oxo-butanoic acid compounds having kynurenine-3-hydroxy base inhibitory activity
    Patent number: 6207709
    Abstract: An N-substituted-2-amino-4-phenyl-4-oxo-butanoic acid compound of the formula (I): wherein X, Y, W and R are as defined herein.
    Type: Grant
    Filed: February 24, 1999
    Date of Patent: March 27, 2001
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Mario Varasi, Antonio Giordani, Massimo Cini, Carmela Speciale, Alberto Bianchetti
  • Recombinant kynurenine-3-hydroxylase enzyme and process for its preparation
    Patent number: 6107069
    Abstract: The present invention provides an isolated polynucleotide encoding for the kynurenine-3-hydrolase (Kyn-3-OHase) and methods of transiently expressing thereof.
    Type: Grant
    Filed: January 14, 1999
    Date of Patent: August 22, 2000
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Simona Magagnin, Luca Benatti, Massimo Cini, Carmela Speciale, Nevie Covini
  • Fluoro-substituted benzoylpropionic acid derivatives
    Patent number: 5973006
    Abstract: A fluoro-substituted benzoylpropionic acid compound of formula (I) either as a single optical isomer or as a mixture of optical isomers ##STR1## wherein R is hydroxy, amino, hydroxylamine, --OR', --NHR', N(R').sub.2 or --NHOR' in which R' is C.sub.1 -C.sub.6 alkyl or benzyl;or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 20, 1998
    Date of Patent: October 26, 1999
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Mario Varasi, Antonio Giordani, Carmela Speciale, Massimo Cini, Alberto Bianchetti