Abstract: A system for the sterilization of hospital waste, comprising a triturator that includes a hermetic cover, a hopper and toothed drums; an auger feeder to transport the triturated waste and comprising nozzles that blow steam into the waste; a high-temperature pressurized steam generator; an airtight sterilization chamber with microwave generators and with an inner stirrer, the sterilization chamber comprising a gate at the top, a gate on one side or in the front, and a stirring device for mixing the contents of the chamber. During the whole process the waste is completely insulated from the external environment. A central unit controls and supervises the operation of all the electric, electronic and mechanical parts of the system, which can be fit into a modular container for easy transportation.