Abstract: A system for assembling and filling two groups of electronic cigarettes, includes first and second working stations for assembly/inspection operations on a first group of electronic cigarettes and disposed upstream and downstream of a first conveying path, respectively. Third and fourth working stations perform assembly/inspection operations on a second group of electronic cigarettes and are disposed upstream and downstream of a second conveying path, respectively. A single filling station receives the first group at a first loading zone and the second group at a second loading zone to fill the first group and the second group with a filling product; and releases the first group of filled electronic cigarettes at a first unloading zone and the second group of filled electronic cigarettes at a second unloading zone towards the second working station and towards the fourth working station, respectively.

Abstract: A method for applying adhesive on a wrapping band of a smoking article includes moving the band along a feed direction, the band has a longitudinal direction of extension, opposing first and second surfaces, a first plurality of portions having a first thickness and a second plurality of portions having a second thickness greater than the first thickness, the portions of the first and second pluralities being disposed alternately along the direction of extension. A nozzle having a delivery end, and the band are moved towards/away from each other between a first position, where the delivery end and the second surface are at a first distance which is less than or equal to the second thickness, and a second position, where the delivery end and the second surface are at a second distance greater than the second thickness. An adhesive is delivered on the first surface through the nozzle.

Abstract: Disclosed are fusion peptides consisting of the peptide fragment corresponding to the N-terminal domain derived from the human TIMP3 protein, both in native and mutated form, bound by the N-terminal end to a highly selective and efficient carrier peptide for transport in renal proximal tubule cells, the medical use thereof, in particular the use thereof in the treatment of diabetic nephropathy, and the compositions comprising them.

Abstract: The present invention concerns methods, in particular in vitro methods, for diagnosing liver fibrosis in a subject suffering from obesity, or for selecting a subject suffering from obesity for liver biopsy or for treatment. The present invention also pertains to methods for screening a probiotic, a prebiotic, a chemical compound or a biological compound suitable for preventing and/or treating liver fibrosis.

Abstract: The present invention concerns methods for diagnosing liver fibrosis in an obese subject, said method comprising the steps of a) determining bacterial diversity in a biological sample from the subject, and b) based on the result of the bacterial diversity determination in step a), diagnosing liver fibrosis in the subject, or comprising the steps of a1) determining the proportion of bacteria belonging to a particular taxon and the proportion of bacteria belonging to at least one other particular taxon, in a biological sample of said subject, a2) combining the proportions determined in step a1) to obtain a combination value, and b) based on the combination value obtained in step a2), diagnosing liver fibrosis in the subject.

Abstract: The present invention concerns methods, in particular in vitro methods, for diagnosing liver fibrosis in a subject suffering from obesity, or for selecting a subject suffering from obesity for liver biopsy or for treatment. The present invention also pertains to methods for screening a probiotic, a prebiotic, a chemical compound or a biological compound suitable for preventing and/or treating liver fibrosis.