Patents by Inventor Massimo Gagna

Massimo Gagna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 5H, 9bH-2a, 4a, 7, 9a-octahydro-tetraazacycloocta?cd!pentalene
    Patent number: 5925753
    Abstract: A process for the preparation of 5H,9bH-2a,4a,7, 9a-octahydrotetraazacycloocta?cd!pentalene of formula (I) ##STR1## which comprises the reaction of 1,4,7,10-tetraazacyclododecane with triethyl orthoformate in the absence of solvent and in the presence of an acid catalyst.
    Type: Grant
    Filed: June 10, 1998
    Date of Patent: July 20, 1999
    Assignee: Dibra S.p.A.
    Inventors: Carlo Felice Viscardi, Marina Ausonio, Massimo Gagna, Carlo Secchi
  • Process for the purification of opacifying contrast agents
    Patent number: 5811581
    Abstract: A process for the purification of opacifying contrastographic agents, comprising chromatographic and nanofiltration techniques combined together, the subsequent chromatographic separation of the crude product solution and a nanofiltration step, with a final deionization on ion exchange resins.
    Type: Grant
    Filed: February 20, 1997
    Date of Patent: September 22, 1998
    Assignee: Dibra S.p.A.
    Inventors: Rodolfo Piva, Carlo Felice Viscardi, Massimo Gagna
  • Process for the preparation of a halosubstituted aromatic acid
    Patent number: 5763650
    Abstract: The present invention refers to a process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid, comprising the following steps:a) catalytic hydrogenation of 5-nitro-1,3-benzenedicarboxylic acid in neutral or basic environment, which gives an aqueous solution of 5-amino-1,3-benzenedicarboxylic acid sodium salt;b) direct iodination of the 5-amino-1,3-benzenedicarboxylic acid sodium salt solution deriving from step a), without further purification, with a solution of ICl in HCl, being the 5-amino-1,3-benzenedicarboxylic acid sodium salt solution previously added with HCl and H.sub.2 SO.sub.4.
    Type: Grant
    Filed: May 13, 1996
    Date of Patent: June 9, 1998
    Assignee: Fructamine S.p.A.
    Inventors: Marina Mauro, Carlo Felice Viscardi, Massimo Gagna
  • Process for the preparation of a dicarboxylic acid dichloride
    Patent number: 5616795
    Abstract: The present invention refers to a process for the preparation of 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid dichloride, comprising the reaction in heterogeneous phase between 5-amino-2,4,6-triiodo-1,3-benzenedicarboxylic acid and thionyl chloride, in a solvent selected from the group consisting of: (C.sub.7 -C.sub.16) linear or branched hydrocarbons, (C.sub.7 -C.sub.8) aromatic hydrocarbons, 1,1,1-trichloroethane, n-butylacetate, diglyme (diethylenglycoledimethylether), and in the presence of a catalytic amount of a tertiary amine.
    Type: Grant
    Filed: May 17, 1996
    Date of Patent: April 1, 1997
    Assignee: Fructamine S.p.A.
    Inventors: Marina Mauro, Carlo F. Viscardi, Massimo Gagna