Patents by Inventor Massimo Iacobelli

Massimo Iacobelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090131362
    Abstract: A study has been carried out to verify the effect of Defibrotide on the activity and expression of Heparanase enzyme on myeloma tumor cells (U266) and human microvascular endothelial cells (HMEC). The study has demonstrated that defibrotide can be effectively used for the manufacture of a medicament for the treatment of diseaseses which are positively affected by the inhibition of Heparanse and/or by the downregulation of Heparanse gene expression, such as diabetes.
    Type: Application
    Filed: May 14, 2007
    Publication date: May 21, 2009
    Applicant: Gentium SPA
    Inventors: Cinara Echart, Laura Iris Ferro, Massimo Iacobelli
  • Publication number: 20080234180
    Abstract: Use of sulgliocotide in the treatment or prevention of mucositis.
    Type: Application
    Filed: May 12, 2005
    Publication date: September 25, 2008
    Applicant: TIUM SPA
    Inventors: Massimo Iacobelli, Laura Iris Ferro
  • Publication number: 20080194506
    Abstract: The use of oligodeoxyribonucleotides having a molecular weight of 4000-10000 Dalton as an anti-tumour agent, alone or in combination with other active ingredients with anti-tumour action, is described. The oligotide may be produced by extraction from animal and/or vegetable tissues, in particular, from mammalian organs, or may be produced synthetically. The tumors which can be treated are preferably angiogenesis-dependent tumors, such as multiple myeloma or breast carcinoma.
    Type: Application
    Filed: February 27, 2006
    Publication date: August 14, 2008
    Applicant: Gentium SPA
    Inventors: Massimo Iacobelli, Gunter Eissner, Laura Iris Ferro
  • Publication number: 20080194507
    Abstract: The use of defibrotide and/or oligodeoxyribonucleotides having a molecular weight of 4000-10000 Dalton as an anti-tumour agent, alone or in combination with other active ingredients with anti-tumour action, is described. The oligotide may be produced by extraction from animal and/or vegetable tissues, in particular, from mammalian organs, or may be produced synthetically. The tumors which can be treated are preferably angiogenesis-dependent tumors, such as multiple myeloma or breast carcinoma.
    Type: Application
    Filed: February 27, 2006
    Publication date: August 14, 2008
    Inventors: Massimo Iacobelli, Gunther Eissner, Laura Iris Ferro
  • Patent number: 6827351
    Abstract: A scraper device for a reciprocating compressor piston rod that comprises at least one scraper ring, provided with at least one lip which faces the surface of the said rod, and a box to contain the scraper ring and for centering on the rod, wherein this scraper ring is produced by means of mechanical processing of deformable plastics materials and wherein this container box is accommodated in support elements with radial play.
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: December 7, 2004
    Assignee: Nuovo Pignone Holding S.p.A.
    Inventors: Franco Graziani, Massimo Iacobelli, Simone Pratesi
  • Publication number: 20030030228
    Abstract: A scraper device (10) for a reciprocating compressor piston rod (11) comprises at least one scraper ring (12, 12′), provided with at least one lip (27, 28) which faces the surface of the said rod (11), and a box (13) to contain the scraper ring (12) and for centring on the rod (11), wherein this scraper ring (12) is produced by means of mechanical processing of deformable plastics materials and wherein this container box (13) is accommodated in support elements (14) with radial play (34).
    Type: Application
    Filed: July 29, 2002
    Publication date: February 13, 2003
    Inventors: Franco Graziani, Massimo Iacobelli, Simone Pratesi