Patents by Inventor Massimo Luigi Capobianco

Massimo Luigi Capobianco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONJUGATES OF BILE ACIDS AND THEIR DERIVATIVES FOR ACTIVE MOLECULES DELIVERY
    Publication number: 20220267780
    Abstract: A conjugate of oligonucleotides and bile acid derivatives having the structure (I), (II) or (III), pharmaceutical compositions thereof, and uses thereof are described.
    Type: Application
    Filed: October 22, 2019
    Publication date: August 25, 2022
    Inventors: Beniamino Palmieri, Matteo Bovolenta, Paola Braghetta, Massimo Luigi Capobianco, Elena Marchesi, Alessandro Medici, Sibilla Molon, Daniela Perrone, Paola Rimessi
  • Oligonucleotide Probes
    Publication number: 20090137789
    Abstract: Fluorescent oligonucleotide probe having a general formula (I), wherein Onu represents an oligonucleotide residue, Thion represents a fluorescent oligothiophene containing n thiophenic rings, n being an integer lower than 8, L representing a binder conceived to maintain Thion mobile in relation to Onu in a manner so that Thion can perform its fluorescent action correctly, and Onu can perform its hybridization action. (I)=Onu-L-Thion.
    Type: Application
    Filed: November 10, 2005
    Publication date: May 28, 2009
    Inventors: Giovanna Barbarella, Massimo Luigi Capobianco, Giovanna Sotgiu, Massimo Zambianchi, Fabio Aruffo, Mario Benzi, Marina Naldi, Umberto Negri
  • Oligonucleotide-anthracycline and oligonucleotide-anthracyclinone conjugates
    Patent number: 6160102
    Abstract: The present invention refers to conjugates formed by a natural or modified oligonucleotide, capable of forming a triple helix with a DNA chain, linked to the aglycone moiety of an anthracycline or to an anthracyclinone via an appropriated linker; such conjugates are capable to bind selectively to specific DNA regions inhibiting their transcription and therefore the formation of the corresponding codified protein.
    Type: Grant
    Filed: September 9, 1998
    Date of Patent: December 12, 2000
    Assignee: Consiglio Nazionale Delle Ricerche
    Inventors: Anna Maria Garbesi, Stefania Bonazzi, Stefania Zanella, Massimo Luigi Capobianco, Giuseppe Giannini, Federico Arcamone