Patents by Inventor Massimo Maffei

Massimo Maffei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250082604
    Abstract: A process of extracting proanthocyanidins (PACs) from plant materials using an ethanol or acetone solvent is described. Plant materials from one or more plant species are mixed with ethanol or acetone at a ratio of extraction solvent to plant material between 3:1 and 8:1. The mixture is then filtered and the filtrate concentrated by evaporation. The extraction process leads to an increase in the total PAC content and in the total A-type PAC content in the degree of polymerization from dimers to pentamers. Formulations containing such PAC-enriched compositions have antioxidant, antibiotic, and antiviral properties and have a negligible allergen content.
    Type: Application
    Filed: September 20, 2024
    Publication date: March 13, 2025
    Inventors: Massimo MAFFEI, Giuseppe MANNINO, Andrea PIANA
  • Patent number: 11029295
    Abstract: A low weight portable air sampling device comprising a housing at least partially enclosing an inlet for receiving an air or breath sample; a removable liner coupled to the inlet containing sorbing materials; a micro-pump for regulating air flow within the device; and an outlet for emitting the air or breath sample from the device is described. The device may be used to collect Volatile Organic Compounds (VOCs) of both biotic and abiotic origin.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: June 8, 2021
    Assignee: TINTORIA PIANA US, INC.
    Inventors: Massimo Maffei, Andrea Piana
  • Publication number: 20200116691
    Abstract: A low weight portable air sampling device comprising a housing at least partially enclosing an inlet for receiving an air or breath sample; a removable liner coupled to the inlet containing sorbing materials; a micro-pump for regulating air flow within the device; and an outlet for emitting the air or breath sample from the device is described. The device may be used to collect Volatile Organic Compounds (VOCs) of both biotic and abiotic origin.
    Type: Application
    Filed: October 11, 2018
    Publication date: April 16, 2020
    Inventors: Massimo Maffei, Andrea Piana
  • Patent number: 7754218
    Abstract: To improve the stability of vaccines comprising aluminum salt(s), the invention uses the amino acid histidine. This can improve pH stability and adjuvant adsorption and can reduce antigen hydrolysis. Histidine is preferably present during adsorption to the aluminum salt(s). The antigen in the vaccine may be a protein or a saccharide and is preferably from N. meningitidis.
    Type: Grant
    Filed: January 3, 2008
    Date of Patent: July 13, 2010
    Assignee: Novartis Caccines and Diagnostics SRL
    Inventors: Mario Contorni, Massimo Maffei
  • Publication number: 20080160045
    Abstract: To improve the stability of vaccines comprising aluminum salt(s), the invention uses the amino acid histidine. This can improve pH stability and adjuvant adsorption and can reduce antigen hydrolysis. Histidine is preferably present during adsorption to the aluminum salt(s). The antigen in the vaccine may be a protein or a saccharide and is preferably from N. meningitidis.
    Type: Application
    Filed: January 3, 2008
    Publication date: July 3, 2008
    Applicant: Novartis Vaccines and Diagnostics, s.r.l.
    Inventors: Mario Contorni, Massimo Maffei
  • Patent number: 7348006
    Abstract: To improve the stability of vaccines comprising aluminum salt(s), the invention uses the amino acid histidine. This can improve pH stability and adjuvant adsorption and can be reduce antigen hydrolysis. Histidine is preferably presen during adsorption to the aluminium salt(s). The antigen in the vaccine may be a protein or a saccharide and is preferably from N. meningitidis.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: March 25, 2008
    Assignee: Novartis Vaccines and Diagnostics, s.r.l.
    Inventors: Mario Contorni, Massimo Maffei
  • Publication number: 20050158334
    Abstract: To improve the stability of vaccines comprising aluminum salt(s), the invention uses the amino acid histidine. This can improve pH stability and adjuvant adsorption and can be reduce antigen hydrolysis. Histidine is preferably presen during adsorption to the aluminium salt(s). The antigen in the vaccine may be a protein or a saccharide and is preferably from N. meningitidis.
    Type: Application
    Filed: July 26, 2002
    Publication date: July 21, 2005
    Inventors: Mario Contorni, Massimo Maffei
  • Patent number: RE45587
    Abstract: To improve the stability of vaccines comprising aluminum salt(s), the invention uses the amino acid histidine. This can improve pH stability and adjuvant adsorption and can reduce antigen hydrolysis. Histidine is preferably present during adsorption to the aluminum salt(s). The antigen in the vaccine may be a protein or a saccharide and is preferably from N. meningitidis.
    Type: Grant
    Filed: February 2, 2012
    Date of Patent: June 30, 2015
    Assignee: GlaxoSmithKline Biologicals SA
    Inventors: Mario Contorni, Massimo Maffei