Abstract: Image analysis method for quantitative assessment of a degree of coordination of uterine motion, comprising: obtaining a recording of a uterus; tracking, in the recording, at least two propagation waves of uterine motion in at least two different regions of the uterus and/or on at least two different times; and determining the degree of coordination of the uterine motion based on a similarity measure of at least two characteristics of the at least two propagation waves.

Abstract: A self-powered vibration mechanism is provided that can be mounted on an existing pedal shaft yet operates independent from the existing pedal. Mechanical isolation or mechanical decoupling permits transferring the vibrating energy to the foot rather than to the pedal shaft and the bicycle. In another embodiment, a full removable pedal with self-powered vibration mechanism can replace an existing pedal.

Abstract: Some embodiments relate to a system and method of estimating the viscoelasticity of a material. The system and method includes receiving a plurality of time-amplitude curves measured at a plurality of space points. The time-amplitude curves reflect time evolutions of a propagating mechanical wave. The system and method also include estimating the viscoelasticity of a material between any set of space points using the time-amplitude curves measured at those space points.

Abstract: Some embodiments are directed to a method for quantitative visualization of uterine strain. The method includes receiving a number of 2D or 3D image frames acquired via an imaging technique and selecting a number of confidential points, determining the orientation of the uterus using the confidential points, selecting a region of interest, generating a grid of tracking points inside the region of interest and tracking and estimating the displacement of tracking points between frames. From a varying distance between each couple or set of tracking points, a strain is calculated. The orientation of the grid of tracking points and of the calculated strain is dependent on the determined orientation of the uterus.

Abstract: A self-powered vibration mechanism is provided that can be mounted on an existing pedal shaft yet operates independent from the existing pedal. Mechanical isolation or mechanical decoupling permits transferring the vibrating energy to the foot rather than to the pedal shaft and the bicycle. In another embodiment, a full removable pedal with self-powered vibration mechanism can replace an existing pedal.

Abstract: Some embodiments are directed to a method of estimating a velocity of a contrast agent. The method includes receiving a plurality of video frames that were produced using a dynamic contrast enhanced imaging process, each video frame including a plurality of pixels/voxels. Information from the video frames is used to estimate velocity vectors indicating the velocity and direction of the agent with the vascular networks. The estimated velocity can be used to diagnose cancer, such as prostate cancer. Instead of velocity vectors, agent trajectories can be determined also used for the same purpose.

Abstract: Some embodiments are directed to a method for quantitative visualization of uterine strain. The method includes receiving a number of 2D or 3D image frames acquired via an imaging technique and selecting a number of confidential points, determining the orientation of the uterus using the confidential points, selecting a region of interest, generating a grid of tracking points inside the region of interest and tracking and estimating the displacement of tracking points between frames. From a varying distance between each couple or set of tracking points, a strain is calculated. The orientation of the grid of tracking points and of the calculated strain is dependent on the determined orientation of the uterus.

Abstract: Some embodiments are directed to a method of estimating a velocity of a contrast agent. The method includes receiving a plurality of video frames that were produced using a dynamic contrast enhanced imaging process, each video frame including a plurality of pixels/voxels. Information from the video frames is used to estimate velocity vectors indicating the velocity and direction of the agent with the vascular networks. The estimated velocity can be used to diagnose cancer, such as prostate cancer. Instead of velocity vectors, agent trajectories can be determined also used for the same purpose.

Abstract: Some embodiments relate to a system and method of estimating the viscoelasticity of a material. The system and method includes receiving a plurality of time-amplitude curves measured at a plurality of space points. The time-amplitude curves reflect time evolutions of a propagating mechanical wave. The system and method also include estimating the viscoelasticity of a material between any set of space points using the time-amplitude curves measured at those space points.

Abstract: A method of determining microvascular architecture is disclosed. Dynamic contrast-enhanced magnetic resonance data acquired from a contrast agent administered to at least a part of a subject to be examined. From the dynamic contrast-enhanced magnetic resonance data a leakage parameter (kep) and a dispersion parameter (k) are computed. Effects of both convective dispersion and extravasation kinetics of contrast agent are taken into account.

Abstract: A method of determining microvascular architecture is disclosed. Dynamic contrast-enhanced magnetic resonance data acquired from a contrast agent administered to at least a part of a subject to be examined. From the dynamic contrast-enhanced magnetic resonance data a leakage parameter (kep) and a dispersion parameter (?) are computed. Effects of both convective dispersion and extravasation kinetics of contrast agent are taken into account.

Abstract: The invention relates to using a perfusion scanning medical imaging technique to generate an image of a perfusable structure of an organism. A fluid is flowing through the structure, and a dose of a traceable agent is present in the fluid. The evolution of the spatial concentration of the agent, e.g., a set of values of the magnitude of the concentration assumed at various moments over a period of time, is determined for a plurality of locations within the structure. The spatial pattern of the evolutions is analyzed and an image is generated on the basis of this analysis in order to enable the medical practitioner to draw conclusions about the dispersion characteristics of the perfusable structure.

Abstract: The invention relates to using a perfusion scanning medical imaging technique to generate an image of a perfusable structure of an organism. A fluid is flowing through the structure, and a dose of a traceable agent is present in the fluid. The evolution of the spatial concentration of the agent, e.g., a set of values of the magnitude of the concentration assumed at various moments over a period of time, is determined for a plurality of locations within the structure. The spatial pattern of the evolutions is analyzed and an image is generated on the basis of this analysis in order to enable the medical practitioner to draw conclusions about the dispersion characteristics of the perfusable structure.

Abstract: A method and an arrangement for determining indicator dilution curves and cardiac parameters of a human or animal body having a central bloodstream comprising an indicator periodically passing one or more locations of the body. An ultrasound signal is applied to the indicator in the central bloodstream and ultrasound measurements are taken from a return signal in response to the ultrasound signal, of at least a first cycle of the indicator. From the ultrasound measurements an indicator concentration time signal is determined. The indicator is of such a low concentration that there is a descriptive relation between the measurements and the indicator concentration time signal. From the first cycle of the indicator concentration time signal an indicator dilution curve is modelled and the modelled indicator dilution curve is adjusted over a time interval. The time interval corresponds to at least part of the first cycle leading a further cycle of the indicator.