Patents by Inventor Massimo Pietropaolo

Massimo Pietropaolo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigen associated with type 1 Diabetes Mellitus
    Patent number: 6930181
    Abstract: A 69 kD protein, designated PM-1, is expressed in human pancreatic islet cells and a human insulinoma. The amino acid sequence of the protein has been determined. Autoantibodies to the PM-1 protein have been found in sera of prediabetic patients. Natural, synthetic or recombinant forms of the PM-1 protein can be used in immunochemical assays to detect anti-PM-1-autoantibodies and to identify patients at risk of developing diabetes.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 16, 2005
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Massimo Pietropaolo, George S. Eisenbarth
  • Antigen associated with Type I diabetes mellitus
    Patent number: 5908627
    Abstract: A 69 kD protein, designated PM-1, is expressed in human pancreatic islet cells and a human insulinoma. The amino acid sequence of the protein has been determined. Autoantibodies to the PM-1 protein have been found in sera of prediabetic patients. Natural, synthetic or recombinant forms of the PM-1 protein can be used in immunochemical assays to detect anti-PM-1-autoantibodies and to identify patients at risk of developing diabetes.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 1, 1999
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Massimo Pietropaolo, George S. Eisenbarth
  • Antigen associated with type I diabetes mellitus
    Patent number: 5891437
    Abstract: A 69 kD protein, designated PM-1, is expressed in human pancreatic islet cells and a human insulinoma. The amino acid sequence of the protein has been determined. Autoantibodies to the PM-1 protein have been found in sera of prediabetic patients. Natural, synthetic or recombinant forms of the PM-1 protein can be used in immunochemical assays to detect anti-PM-1-autoantibodies and to identify patients at risk of developing diabetes.
    Type: Grant
    Filed: September 16, 1994
    Date of Patent: April 6, 1999
    Inventors: Massimo Pietropaolo, George S. Eisenbarth