Patents by Inventor Massimo Resnati

Massimo Resnati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies specific for the chemotactic epitope of the urokinase-type plasminogen activator receptor
    Patent number: 7951589
    Abstract: The present invention describes monoclonal antibodies specific for the chemotactic epitope of the uPAR. In particular, the invention comprises monoclonal antibodies against uPAR fragments specifically recognizing in whole or in part the chemotactic sequence of uPAR connecting domain 1 to domain 2.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: May 31, 2011
    Assignee: Wilex AG
    Inventors: Massimo Resnati, Francesco Blasi, Nicolai Sidenius, Isabella Pallavicini
  • METHODS AND AGENTS MODULATING UPA/UPAR ACTIVITY
    Publication number: 20110027285
    Abstract: This invention herein disclosed relates to the anti-HIV action of uPAR-activators or activated uPAR molecules, the control of chemotaxis and cell migration by agents interfering with uPAR activation, a method for determining activated uPAR forms, the use of agents interfering with uPA/uPAR interaction for the diagnosis or therapy of diseases.
    Type: Application
    Filed: April 6, 2010
    Publication date: February 3, 2011
    Applicant: FONDAZIONE CENTRO SAN RAFFAELE MONTE TABOR
    Inventors: FRANCESCO BLASI, NICOLAI SIDENIUS, MASSIMO RESNATI, ANNA MONDINO, GUIDO POLI, MASSIMO ALFANO
  • Antibody against uPA/uPAR
    Patent number: 7737256
    Abstract: The invention herein disclosed relates to the anti-HIV action of uPAR-activators or activated uPAR molecules, the control of chemotaxis and cell migration by agents interfering with uPAR activation, a method for determining activated uPAR forms, the use of agents interfering with uPA/uPAR interaction for the diagnosis or therapy of diseases.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: June 15, 2010
    Assignee: Fondazione Centro San Raffaele Del Monte Tabor
    Inventors: Francesco Blasi, Nicolai Sidenius, Massimo Resnati, Anna Mondino, Guido Poli, Massimo Alfano
  • MONOCLONAL ANTIBODIES AND IMMUNODETECTION ASSAY SPECIFIC FOR THE CHEMOTACTIC EPITOPE OF THE UROKINASE-TYPE PLASMINOGEN ACTIVATOR RECEPTOR
    Publication number: 20090202550
    Abstract: The present invention describes monoclonal antibodies specific for the chemotactic epitope of the uPAR. In particular, the invention comprises monoclonal antibodies against uPAR fragments specifically recognizing in whole or in part the chemotactic sequence of uPAR connecting domain 1 to domain 2.
    Type: Application
    Filed: March 10, 2006
    Publication date: August 13, 2009
    Applicant: WILEX AG
    Inventors: Massimo Resnati, Francesco Blasi, Nicolai Sidenius, Isabella Pallavicini
  • Therapeutic Peptides Derived from Urokinase Plasminogen Activator Receptor
    Publication number: 20080280833
    Abstract: The present invention relates to a chemotactically active epitope derivable from the urokinase receptor, a mutated peptide that acts as an inhibitor of chemotaxis, and their therapeutic use.
    Type: Application
    Filed: January 31, 2006
    Publication date: November 13, 2008
    Inventors: Bernard Degryse, Massimo Resnati, Ralf-Peter Czekay, David J. Loskutoff, Francesco Blasi
  • Methods and agents modulating upa/upar activity
    Publication number: 20040115190
    Abstract: The invention herein disclosed relates to the anti-HIV action of uPAR-activators or activated uPAR molecules, the control of chemotaxis and cell migration by agents interfering with uPAR activation, a method for determining activated uPAR forms, the use of agents interfering with uPA/uPAR interaction for the diagnosis or therapy of diseases.
    Type: Application
    Filed: January 29, 2004
    Publication date: June 17, 2004
    Inventors: Francesco Blasi, Nicolai Sidenius, Massimo Resnati, Anna Mondino, Guido Poli, Massimo Alfano
  • UPAR mimicking peptide
    Patent number: 6462170
    Abstract: Peptides comprising the SRSRY sequence (SEQ ID NO: 7) derived from the uPAR (urokinase receptor) are endowed with chemotactic activity, making them useful for preventing or activating the migration of cells in a mammal. More particularly, the peptides of the invention are useful for the treatment of cancer, autoimmune diseases, and/or hyperinflammatory diseases and for stimulating wound healing.
    Type: Grant
    Filed: October 20, 1999
    Date of Patent: October 8, 2002
    Assignees: Fondazione Centro San Raffaele del Monte Tabor, Universita Degli Studi di Milano
    Inventors: Francesco Blasi, Francesca Fazioli, Massimo Resnati, Nicolai Sidenius