Patents by Inventor Masumi Murakami

Masumi Murakami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-2 VARIANT
    Publication number: 20210060169
    Abstract: An object of the present invention is to provide a novel IL-2 variant which has improved selectivity for IL-2R??? and selectively activates Tregs. The present invention relates to an IL-2 variant, a method for producing the IL-2 variant, a composition and a therapeutic agent for an immune disease, comprising the IL-2 variant, a method for increasing selectivity of IL-2 for IL-2R???, a method for improving an affinity of IL-2 for an IL-2R? subunit, a method of reducing an affinity of IL-2 for at least one of an IL-2R? subunit and an IL-2R? subunit, and a method for selectively activating regulatory T cells.
    Type: Application
    Filed: December 27, 2018
    Publication date: March 4, 2021
    Applicant: Kyowa Kirin Co., Ltd.
    Inventors: Masahiro IKEDA, Shinpei YAMAGUCHI, Masumi MURAKAMI, Hideyuki ONODERA
  • Method for producing glycopeptide having sialyl sugar chain, sialyl sugar chain-added amino acid derivative to be used in same, and glycopeptide
    Patent number: 9073978
    Abstract: [Technical Problem] To provide a method for manufacturing that enables to obtain a targeted glycopeptide harboring a sialyl sugar chain in high yield without decomposing sialic acid at a non-reducing terminal of sugar chain when the glycopeptide is synthesized by a Boc solid phase synthesis method. [Solution to Problem] The present invention is characterized in that the Boc-sialylglycosylated amino acid derivative used in Boc solid phase synthesis method is one where the carboxyl group of the sialic acid at the sugar chain non-reducing terminal is protected with a phenacyl group.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: July 7, 2015
    Assignee: Glytech, Inc.
    Inventors: Yasuhiro Kajihara, Masumi Murakami, Kazuyuki Ishii
  • Reagent and reagent kit for measurement of FDP, and measurement method
    Patent number: 8865425
    Abstract: The present invention relates to a reagent for the measurement of FDP comprising a carrier sensitized with at least two monoclonal antibodies selected from three monoclonal antibodies having different reactivity towards FDP. The present invention also relates to a reagent kit comprising the reagent and a method for measurement of FDP using the reagent or reagent kit.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: October 21, 2014
    Assignee: Sysmex Corporation
    Inventors: Katsushi Kobayashi, Masumi Murakami, Mayumi Sugimoto
  • Anti-FDP monoclonal antibody, FDP measurement reagent and reagent kit using same, and FDP measurement method
    Patent number: 8865424
    Abstract: The present invention relates to an anti-FDP monoclonal antibody selected from the first, second and third monoclonal antibodies having different reactivity towards FDP. The present invention also relates to a reagent and reagent kit for the measurement of FDP and a method for measurement of FDP using the anti-FDP monoclonal antibodies.
    Type: Grant
    Filed: January 28, 2013
    Date of Patent: October 21, 2014
    Assignee: Sysmex Corporation
    Inventors: Naoya Okitsu, Katsushi Kobayashi, Noriaki Nakajima, Masumi Murakami, Kouji Sakaguchi, Ayumi Asaeda, Mayumi Sugimoto
  • Method for Producing Glycopeptide Having Sialyl Sugar Chain, Sialyl Sugar Chain-Added Amino Acid Derivative to be Used in Same, and Glycopeptide
    Publication number: 20140058062
    Abstract: [Technical Promblem] To provide a method for manufacturing that enables to obtain a targeted glycopeptide harboring a sialyl sugar chain in high yield without decomposing sialic acid at a non-reducing terminal of sugar chain when the glycopeptide is synthesized by a Boc solid phase synthesis method. [Solution to Problem] The present invention is characterized in that the Boc-sialylglycosylated amino acid derivative used in Boc solid phase synthesis method is one where the carboxyl group of the sialic acid at the sugar chain non-reducing terminal is protected with a phenacyl group.
    Type: Application
    Filed: March 5, 2012
    Publication date: February 27, 2014
    Applicant: Glytech, Inc.
    Inventors: Yasuhiro Kajihara, Masumi Murakami, Kazuyuki Ishii
  • ANTI-FDP MONOCLONAL ANTIBODY, FDP MEASUREMENT REAGENT AND REAGENT KIT USING SAME, AND FDP MEASUREMENT METHOD
    Publication number: 20130149793
    Abstract: The present invention relates to an anti-FDP monoclonal antibody selected from the first, second and third monoclonal antibodies having different reactivity towards FDP. The present invention also relates to a reagent and reagent kit for the measurement of FDP and a method for measurement of FDP using the anti-FDP monoclonal antibodies.
    Type: Application
    Filed: January 28, 2013
    Publication date: June 13, 2013
    Inventors: Naoya OKITSU, Katsushi KOBAYASHI, Noriaki NAKAJIMA, Masumi MURAKAMI, Kouji SAKAGUCHI, Ayumi ASAEDA, Mayumi SUGIMOTO
  • IMMUNOCHROMATOGRAPHIC TEST DEVICE
    Publication number: 20090087926
    Abstract: The invention provides an immunochromatographic test device for detecting a test substance in a sample, comprising a chromatographic membrane carrier; a sample developing member; and a labeling substance holding member; wherein a substance being capable of reacting to a human anti-mouse antibody is held in a member disposed at a position which is more upstream on the basis of the sample developing direction than the chromatographic membrane carrier, as well as an a method for detecting a test substance in a sample by using an immunochromatographic test device and a method for manufacturing an immunochromatographic test device.
    Type: Application
    Filed: August 13, 2008
    Publication date: April 2, 2009
    Applicant: SYSMEX CORPORATION
    Inventors: Takehiro HASEGAWA, Masumi Murakami, Takeshi Imoarai