Patents by Inventor Masuo Aizawa

Masuo Aizawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Light emitting method of acridinium derivative and method of detecting substance to be examined using same
    Patent number: 5879888
    Abstract: A light emitting method of an acridinium ester, comprising reacting said acridinium ester and a superoxide anion, and a method of detecting a substance to be examined, comprising detecting a light emitted by reacting a superoxide anion with an acridinium ester used as a label are described. It is possible to carry out the reaction not under strongly alkaline conditions but around the neutral point and to generate strong luminescence which is stable over a long period of time.
    Type: Grant
    Filed: October 30, 1996
    Date of Patent: March 9, 1999
    Assignee: Iatron Laboratories, Inc.
    Inventors: Masuo Aizawa, Yoshihito Ikariyama, Eiry Kobatake, Minoru Ogasawara, Mitsunao Tanaka
  • Homogeneous amperometric immunoassay
    Patent number: 5346832
    Abstract: A method is described for measuring the amount of analyte present in a sample containing the analyte using a homogeneous amperometric immunoassay. The analyte is chemically bonded to a suitable carrier molecule, which is also chemically bonded to an electroactive molecule. The electroactive molecule, such as ferrocene carboxylic acid, contains a redox center which is capable of transferring a charge to an electrode. A preferred carrier molecule is bovine serum albumin (BSA), while suitable analytes include digoxin, theophylline and HCG. The immunoassay is conveniently performed by applying a voltage to a set of electrodes.
    Type: Grant
    Filed: December 18, 1992
    Date of Patent: September 13, 1994
    Assignee: Ciba Corning Diagnostics Corp.
    Inventors: Masuo Aizawa, Brenda D. Manning, Miki Hidaka, Laura S. Uretsky
  • Homogeneous amperometric immunoassay
    Patent number: 5198367
    Abstract: A method is described for measuring the amount of analyte present in a sample containing the analyte using a homogeneous amperometric immunoassay. The analyte is covalently bonded to a suitable carrier molecule, which is also covalently bonded to an electroactive molecule. The electroactive molecule, such as ferrocene carboxylic acid, contains a redox center which is capable of transferring a charge to an electrode. A preferred carrier molecule is bovine serum albumin (BSA), while suitable analytes include digoxin, theophylline and HCG. The immunoassay is conveniently performed by applying a voltage to a set of electrodes.
    Type: Grant
    Filed: June 9, 1989
    Date of Patent: March 30, 1993
    Inventors: Masuo Aizawa, Brenda D. Manning, Miki Hidaka, Laura S. Uretsky
  • Electrochemical measuring apparatus provided with an enzyme electrode
    Patent number: 4388166
    Abstract: An electrochemical measuring apparatus which essemtially comprises an asymmetric semipermeable membrane mounted on an immobilized enzyme membrane of an enzyme electrode, said asymmetric semipermeable membrane being essentially formed of a thin semipermeable layer exposed to the outside for contact with a liquid to be measured and an inner adjacent thick porous layers, and can measure an organic ingredient such as glucose contained in blood or serum with high sensitivity in a short time and moreover has a prominent durability.
    Type: Grant
    Filed: May 15, 1982
    Date of Patent: June 14, 1983
    Assignee: Tokyo Shibaura Denki Kabushiki Kaisha
    Inventors: Shuichi Suzuki, Masuo Aizawa, Masao Koyama, Yuichi Sato, Junji Koezuka
  • Antigen membranes for use in syphilis diagnosis and syphilis diagnosis apparatus using such membranes
    Patent number: 4081334
    Abstract: An antigen membrane for syphilis diagnosis comprises cardiolipin immobilized in a polymer maxtrix. The membranes are used in syphilis diagnosis and in an apparatus for syphilis diagnosis.
    Type: Grant
    Filed: March 18, 1977
    Date of Patent: March 28, 1978
    Assignee: Nippon Chemiphar Co., Ltd.
    Inventors: Shuichi Suzuki, Masuo Aizawa, Isao Ishigur, Rikio Shinohara, Yoichi Nagamura
  • Luminescence by reacting an acridinium ester with superoxide
    Patent number: RE39047
    Abstract: A light emitting method of an acridinium ester, comprising reacting said acridinium ester and a superoxide anion, and a method of detecting a substance to be examined, comprising detecting a light emitted by reacting a superoxide anion with an acridinium ester used as a label am described. It is possible to carry out the reaction not under strongly alkaline conditions but around the neutral point and to generate strong luminescence which is stable over a long period of time.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: March 28, 2006
    Assignee: Mitsubishi Kagaku Iatron, Inc.
    Inventors: Masuo Aizawa, Michiko Ikariyama, Eiry Kobatake, Minoru Ogasawara, Mitsunao Tanaka, Yoshihito Ikariyama