Patents by Inventor Matam Shiva Kumar

Matam Shiva Kumar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated bacterial strain of sp. MTCC 5605 and a highly enantioselective epoxide hydrolase isolated therefrom
    Patent number: 9150840
    Abstract: The present invention relates to a novel epoxide hydrolase enzyme which aims to achieve a high degree of resolution towards a broader range of substrates with high enantioselectivity and yields with minimal product inhibition. The invention further relates to a new bacterial strain Achromobacter sp. MTCC 5605 isolated from a petroleum-contaminated sludge sample, capable of producing the said enzyme. It is notable that the enzyme can be used as whole bacterial cell preparation, which allows continuous hydrolysis of substrates at even higher concentration and have an advantage of being recycled. The invention further relates to a process for the hydrolysis of different aryl epoxides which are potential synthons of intermediates for the synthesis of chiral amino alcohols and bioactive compounds like ?-blockers.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: October 6, 2015
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Ahmed Kamal, Rohini Khanna, Chityal Ganesh Kumar, Anver Basha Shaik, Matam Shiva Kumar
  • NOVEL BACTERIAL STRAIN OF ACHROMOBACTER SP. MTCC 5605 AND A HIGHLY ENANTIOSELECTIVE EPOXIDE HYDROLASE ISOLATED THEREFROM
    Publication number: 20140011224
    Abstract: The present invention relates to a novel epoxide hydrolase enzyme which aims to achieve a high degree of resolution towards a broader range of substrates with high enantioselectivity and yields with minimal product inhibition. The invention further relates to a new bacterial strain Achromobacter sp. MTCC 5605 isolated from a petroleum-contaminated sludge sample, capable of producing the said enzyme. It is notable that the enzyme can be used as whole bacterial cell preparation, which allows continuous hydrolysis of substrates at even higher concentration and have an advantage of being recycled. The invention further relates to a process for the hydrolysis of different aryl epoxides which are potential synthons of intermediates for the synthesis of chiral amino alcohols and bioactive compounds like ?-blockers.
    Type: Application
    Filed: August 27, 2012
    Publication date: January 9, 2014
    Applicant: Council of Scientific & Industrial Research
    Inventors: Ahmed Kamal, Rohini Khanna, Chityal Ganesh Kumar, Anver Basha Shaik, Matam Shiva Kumar