Patents by Inventor Matazaemon Uchida

Matazaemon Uchida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5098928
    Abstract: The ketenedithioacetal derivatives of formula (I) have a potent hypolipidemic and anti-arteriosclerotic effect and are useful for prophylaxis and treatment of arteriosclerosis or hyperlipidemia.
    Type: Grant
    Filed: October 25, 1990
    Date of Patent: March 24, 1992
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Masashi Nagamine, Kunikazu Hiraga, Atsushi Sakai, Matazaemon Uchida
  • Patent number: 5045562
    Abstract: 1,3,5-trithiane derivatives represented by the formula (I) ##STR1## wherein the substituents are defined herein, are disclosed. The trithiane derivatives and their compositions are useful as anti-arteriosclerotic or anti-hyperlipemic agents.
    Type: Grant
    Filed: October 17, 1988
    Date of Patent: September 3, 1991
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Masashi Nagamine, Kunikazu Hiraga, Atsushi Sakai, Matazaemon Uchida
  • Patent number: 5041440
    Abstract: Novel dithiolane derivatives of formula: ##STR1## wherein X is, a C.sub.2 -C.sub.7 alkylcarbonyl group, benzoyl group, benzoyl group substituted with 1-3 groups selected from halogen, C.sub.1 -C.sub.4 alkyl, and C.sub.1 -C.sub.4 alkoxy; Y represents C.sub.2 -C.sub.7 alkylcarbonyl group, C.sub.2 -C.sub.7 alkoxycarbonyl group or cyano group; and R represents di (C.sub.1 -C.sub.4 alkylamino) group, morpholino group or piperidino group, are produced by reacting glyoxal sodium bisulfite adduct with amine compounds in the presence of acids and then with dithiolates. The dithiolane derivatives can activate liver functions and are effective for treatment and prophylaxis of hepatitis and other hepatic disorders.
    Type: Grant
    Filed: August 22, 1989
    Date of Patent: August 20, 1991
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Shuhei Kubota, Kunikazu Hiraga, Keisuke Nakayama, Matazaemon Uchida
  • Patent number: 4910217
    Abstract: A curing agent for fat necrosis which contains a dithia derivative represented by the general formula ##STR1## wherein R and R.sup.1 may be either the same or different and denote a lower alkyl group; n denotes an integer of 0, 1 or 2; and A denotes --CH.sub.2 --, ##STR2## M being H or a salt-forming rest, --CH.dbd.CH--, --CH.sub.2 CH.sub.2 --, or ##STR3## and a method for curing said disease using the said curing agent.
    Type: Grant
    Filed: December 24, 1986
    Date of Patent: March 20, 1990
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Matazaemon Uchida, Masakazu Shibayama, Isao Nishino, Harutaka Kimura
  • Patent number: 4863925
    Abstract: A cyclohexanedione derivative represented by the general formula (I); ##STR1## wherein R.sup.1, R.sup.4 and R.sup.7 represent independently hydrogen atom or C.sub.1 -C.sub.8 alkyl group, R.sup.2 represents hydrogen atom; C.sub.1 -C.sub.8 alkyl group; C.sub.2 -C.sub.6 alkenyl group; C.sub.3 -C.sub.8 cycloalkyl group; C.sub.2 -C.sub.7 alkoxycarbonyl group; C.sub.1 -C.sub.6 alkylthio C.sub.1 -C.sub.6 alkyl group; a phenyl group; a phenyl group substituted with 1 to 3 groups selected from the group consisting of halogen atom, C.sub.1 -C.sub.6 alkyl group, C.sub.1 -C.sub.6 haloalkyl group, C.sub.1 -C.sub.6 alkoxy group, C.sub.1 -C.sub.6 alkylthio group, C.sub.3 -C.sub.8 cycloalkoxy group, a benzyloxy group and a benzyloxy group substituted with C.sub.1 -C.sub.6 alkoxy group; naphthyl group or a heterocyclic group, R.sup.3 represents hydrogen atom, C.sub.1 -C.sub.8 alkyl group or C.sub.2 -C.sub.7 alkoxycarbonyl group, and R.sup.5 and R.sup.6, which may be the same or different, represent hydrogen atom, C.sub.1 -C.
    Type: Grant
    Filed: September 22, 1987
    Date of Patent: September 5, 1989
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Shuhei Kubota, Kunikazu Hiraga, Keisuke Nakayama, Matazaemon Uchida
  • Patent number: 4835153
    Abstract: This invention relates to a malonic acid derivative represented by the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2, which may be the same or different, represents hydrogen atom; C.sub.1 -C.sub.12 alkyl group; C.sub.1 -C.sub.8 alkyl group substituted with C.sub.1 -C.sub.5 alkoxy group, a tetrahydrofuryl group, a phenyl group or a phenyl group substituted with 1 to 3 groups selected from the group consisting of halogen atoms, C.sub.1 -C.sub.5 alkyl groups and C.sub.1 -C.sub.5 alkoxy groups; or C.sub.2 -C.sub.6 alkenyl group; R.sup.3 and R.sup.4, which may be the same or different, represent hydrogen atom, C.sub.1 -C.sub.6 alkyl group, C.sub.2 -C.sub.6 alkenyl group, C.sub.2 -C.sub.8 alkoxyalkyl group, benzoyl group, C.sub.2 -C.sub.8 alkylcarbonyl group, C.sub.2 -C.sub.8 alkoxycarbonyl group, C.sub.1 -C.sub.4 alkylsulfonyl group or aralkyl group including benzyl group, and R.sup.5, R.sup.6 and R.sup.7, which may be the same or different, represent hydrogen atom or C.sub.1 -C.sub.
    Type: Grant
    Filed: August 28, 1987
    Date of Patent: May 30, 1989
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Shuhei Kabota, Kunikazu Hiraga, Keisuke Nakayama, Matazaemon Uchida, Kuniaki Taninaka
  • Patent number: 4816475
    Abstract: An anti-arteriosclerotic or anti-hyperlipemic 1,3,5-trithiane derivative according to the formula (I): ##STR1## a pharmaceutical composition containing the same, and a process for producing the same.
    Type: Grant
    Filed: July 14, 1987
    Date of Patent: March 28, 1989
    Assignee: Nihon Nohyaku Co. Ltd.
    Inventors: Masashi Nagamine, Kunikazu Hiraga, Atsushi Sakai, Matazaemon Uchida
  • Patent number: 4738976
    Abstract: A novel ketene S,S-acetal derivative which is useful as an antimycotic agent and an agricultural chemical of fungicidal, plant growth regulating or insecticidal properties represented by the general formula (I): ##STR1## wherein R represents a hydrogen atom; an alkyl group having 1 to 8 carbon atoms; a cycloalkyl group having 3 to 6 carbon atoms; a methylene group; a lower alkenyl group; a lower alkyl group substituted by a halogen atom, a cyano group, a lower alkoxyl group, a lower alkylthio group; a carbamoyl group, an acyl group, or an alkenoyloxy group; a phenyl group represented by ##STR2## (in which R.sub.
    Type: Grant
    Filed: October 8, 1986
    Date of Patent: April 19, 1988
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Akira Seo, Hideo Kanno, Nobu Hasegawa, Yukio Miyagi, Akira Nishimura, Shigeo Konaka, Tetsuto Ohmi, Yukimi Munechika, Matazaemon Uchida, Kenichi Ikeda
  • Patent number: 4636519
    Abstract: A novel ketene S,S-acetal derivative which is useful as an antimycotic agent and an agricultural chemical of fungicidal, plant growth regulating or insecticidal properties represented by the general formula (I): ##STR1## wherein R represents a hydrogen atom; an alkyl group having 1 to 8 carbon atoms; a cycloalkyl group having 3 to 6 carbon atoms; a methylene group; a lower alkenyl group; a lower alkyl group substituted by a halogen atom, a cyano group, a lower alkoxy group, a lower alkylthio group; a carbamoyl group, an acyl group, or an alkenoyloxy group; a phenyl group represented by ##STR2## (in which R.sub.
    Type: Grant
    Filed: October 10, 1985
    Date of Patent: January 13, 1987
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Akira Seo, Hideo Kanno, Nobu Hasegawa, Yukio Miyagi, Akira Nishimura, Shigeo Konaka, Tetsuto Ohmi, Yukimi Munechika, Matazaemon Uchida, Kenichi Ikeda