Patents by Inventor Mate Kovatsits

Mate Kovatsits has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2,6-bis(chloromethyloxy-carbonyloxymethyl)pyridine and a process for preparing same
    Patent number: 4764613
    Abstract: The invention relates to the novel 2,6-bis(chloromethyloxy-carbonyloxymethyl)pyridine of the formula (I) ##STR1## as well as a process for the preparation of this compound, which is a useful intermediate in the preparation of the anti-atherosclerotic 2,6-bis(hydroxymethyl)pyridine bis(N-methylcarbamate) (pyridinolcarbamate) and other drugs.According to the invention, the compound of the formula (I) is prepared by reacting 2,6-bis(hydroxymethyl)pyridine of the formula (II) ##STR2## with chloromethyl chloroformate of the formula (III) ##STR3## in a polar-aprotic, water-immiscible organic solvent, in the presence of a basic substance between about -30.degree. C. and +10.degree. C.
    Type: Grant
    Filed: August 24, 1987
    Date of Patent: August 16, 1988
    Assignee: Richter Gedeon Vegyeszeti Gyar Rt.
    Inventors: Jozsef Toth, Mate Kovatsits, Laszlo Csutoras, Gabor Szabo, Sandor Gorog, Ferenc Trischler, Sandor Holly, Erzsebet Francsics, Bela Losonczi, Gabor Havasi