Patents by Inventor Matej Avanzo

Matej Avanzo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spray-Freeze Drying of Polyelectrolyte Nanoparticles Containing the Protein Drug
    Publication number: 20170258726
    Abstract: The present invention relates to a process for spray-freeze-drying (SFD) a dispersion of polyelectrolyte complex (PEC) nanoparticles loaded with a protein drug, which yields a powdered product with adequate flowability properties that may readily be processed further into solid dosage forms such as tablets or capsules. The mean particle size of PEC nanoparticles obtained after redispersion of SFD powder or pharmaceutical compositions made from said powder in water is preserved in the nanometer range (<1000 nm), and so is the protein biological activity.
    Type: Application
    Filed: September 18, 2015
    Publication date: September 14, 2017
    Applicant: Lek Pharmaceuticals d.d.
    Inventors: Mateja CEGNAR, Matej AVANZO, Janez KERC, Ana MIKLAVZIN
  • Pharmaceutical composition
    Patent number: 9707178
    Abstract: A pharmaceutical composition comprising an ester of 4-(1-hydroxy-1-methylethyl)-2 propyl-1-[[2?-(1H-tetrazol-5-yl)[1,1?-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid characterized in that when exposed to 75% relative humidity at 40° in open dish for one month the total amount of related substances does not increase more than 1% is described.
    Type: Grant
    Filed: May 2, 2007
    Date of Patent: July 18, 2017
    Assignee: Lek Pharmaceuticals, d.d.
    Inventors: Matej Avanzo, Tanja Rozman Peterka, Igor Legen
  • PHARMACEUTICAL COMPOSITION
    Publication number: 20090238871
    Abstract: A pharmaceutical composition comprising an ester of 4-(1-hydroxy-1-methylethyl)-2 propyl-1-[[2?-(1H-tetrazol-5-yl)[1,1?-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid characterized in that when exposed to 75% relative humidity at 40° in open dish for one month the total amount of related substances does not increase more than 1% is described.
    Type: Application
    Filed: May 2, 2007
    Publication date: September 24, 2009
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Matej Avanzo, Tanja Rozman Peterka, Igor Legen