Patents by Inventor Matheus Maria De Gunst

Matheus Maria De Gunst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • miRNA-193a for Promoting Immunogenic Cell Death
    Publication number: 20230136088
    Abstract: The invention relates to the use of miRNA-193a for regulating gene expression, particularly it relates to the use of miRNA-193a as a CRT agonist, promoting the cell surface expression of CRT. This allows the advantageous treatment of cancers without or with low surface expression of CRT. The invention further relates to compositions comprising the miRNA for use in such treatment.
    Type: Application
    Filed: February 26, 2021
    Publication date: May 4, 2023
    Applicant: INTERNA TECHNOLOGIES B.V.
    Inventors: Sanaz YAHYANEJAD, Bryony TELFORD, Marion VAN DEN BOSCH, Mir Farshid ALEMDEHY, Matheus Maria DE GUNST, Laurens Adrianus Hendricus VAN PINXTEREN, Roeland Quirinus Jozef SCHAAPVELD, Michel JANICOT
  • NEW TREATMENTS INVOLVING MIRNA-193A
    Publication number: 20220275368
    Abstract: The invention relates to the use of miRNA-193a for regulating gene expression, particularly it relates to the use of miRNA-193a as a PTEN agonist. This allows the advantageous treatment of PTEN-deficient cancers. The invention further relates to compositions comprising the miRNA for use as a PTEN agonist.
    Type: Application
    Filed: March 6, 2020
    Publication date: September 1, 2022
    Applicant: INTERNA TECHNOLOGIES B.V.
    Inventors: Sanaz YAHYANEJAD, Bryony Jane TELFORD, Marion Tina Jolien VAN DEN BOSCH, Mir Farshid ALEMDEHY, Matheus Maria DE GUNST, Laurens Adrianus Hendricus VAN PINXTEREN, Roeland Quirinus Jozef SCHAAPVELD, Michel JANICOT
  • ANTICANCER MICRORNA AND LIPID FORMULATIONS THEREOF
    Publication number: 20210038732
    Abstract: The present invention relates to a lipid formulation comprising microRNA. The formulation comprises cationic lipids that can form lipid nanoparticles with the microRNA. The formulations are useful in medicine.
    Type: Application
    Filed: February 12, 2019
    Publication date: February 11, 2021
    Applicant: INTERNA TECHNOLOGIES B.V.
    Inventors: Matheus Maria DE GUNST, Laurens Adrianus Hendricus VAN PINXTEREN, Michel JANICOT, Iman Johannes SCHULTZ, Roeland Quirinus Jozef SCHAAPVELD, Sanaz YAHYANEJAD
  • Combination for use in treating diseases or conditions associated with melanoma, or treating diseases or conditions associated with activated B-raf pathway
    Patent number: 10201556
    Abstract: The invention relates to the therapeutic use of a combination in a disease and condition associated with melanoma or a disease or a condition associated with activated BRAF pathway.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: February 12, 2019
    Assignee: INTERNA TECHNOLOGIES B.V.
    Inventors: Rick Jan van Haastert, Petronella Innocentia van Noort, Grégoire Pierre André Prevost, Willemijn Maria Gommans, Roeland Quirinus Jozef Schaapveld, Matheus Maria De Gunst, Iman Johannes Schultz, Eugene Berezikov
  • Combination for use in treating diseases or conditions associated with melanoma, or treating diseases or conditions associated with activated B-raf pathway
    Publication number: 20150297626
    Abstract: The invention relates to the therapeutic use of a combination in a disease and condition associated with melanoma or a disease or a condition associated with activated BRAF pathway.
    Type: Application
    Filed: November 6, 2013
    Publication date: October 22, 2015
    Applicant: InteRNA Technologies B.V.
    Inventors: Rick Jan van Haastert, Petronella Innocentia van Noort, Grégoire Pierre André Prevost, Willemijn Maria Gommans, Roeland Quirinus Jozef Schaapveld, Matheus Maria De Gunst, Iman Johannes Schultz, Eugene Berezikov