Patents by Inventor Mathew Maye
Mathew Maye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11103923Abstract: A nanoparticle with tunable radial gradients of compositions extending from the center of the nanoparticles. The nature of the gradient preserves the metallic state of the nanoparticles, the diffusion of the constituents, and the oxidation of the interface. The gradients can be purposely varied to allow for specific applications in fields ranging from corrosion, magnetics, information technology, imaging, electromagnetic absorption, coating technologies, and immuno-precipitation. The nanoparticles can be easily used to advance many areas of industry, technology, and life sciences.Type: GrantFiled: November 18, 2016Date of Patent: August 31, 2021Assignee: Syracuse UniversityInventor: Mathew Maye
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Publication number: 20180326479Abstract: A nanoparticle with tunable radial gradients of compositions extending from the center of the nanoparticles. The nature of the gradient preserves the metallic state of the nanoparticles, the diffusion of the constituents, and the oxidation of the interface. The gradients can be purposely varied to allow for specific applications in fields ranging from corrosion, magnetics, information technology, imaging, electromagnetic absorption, coating technologies, and immuno-precipitation. The nanoparticles can be easily used to advance many areas of industry, technology, and life sciences.Type: ApplicationFiled: November 18, 2016Publication date: November 15, 2018Applicant: Syracuse UniversityInventor: Mathew Maye
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Publication number: 20180284086Abstract: A nanoparticle based assay for monitoring chemical reactions in real-time, ion concentrations in solution, and oxidation potential of ions in solution is describe. The assay is based on use of photoluminescent perovskite nanoparticles with the composition XYZ3. The XYZ3 nanoparticles are added to a reaction or a solution to be analyzed, and the optoelectronic response of the nanoparticle is proportional to the chemical kinetics of the reaction or concentration of target. The resulting color changes can be qualitatively monitored by eye or quantitatively by spectroscopy. The assays may serve as a compliment or replacement for routine chemical analysis performed over the course of a reaction.Type: ApplicationFiled: August 30, 2016Publication date: October 4, 2018Applicant: Syracuse UniversityInventors: Mathew Maye, Tennyson Doane
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Patent number: 9758808Abstract: A bioluminescence energy transfer (BRET) nanosystem having semiconductive quantum rods (QRs) bound by firefly luciferase Photinus pyralis (Ppy) for improved conversion of chemical energy to light, such as in solid-state lighting, near-infrared imaging systems, and in vivo infrared imaging. The nanosystems are formed by synthesizing CdSe/CdS or CdSe/CdS/ZnS quantum rods, rendering the dots hydrophilic and colloidially stable with a facile His-capping, incubating with a Ppy variant (PpyGRTS) at increasing loading ratios, and adding an excess of the luciferin (LH2) substrate to the PpyGRTS-QRs.Type: GrantFiled: November 6, 2013Date of Patent: September 12, 2017Assignee: SYRACUSE UNIVERSITYInventors: Mathew Maye, Rabeka Alam
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Patent number: 8632789Abstract: System and method for loading the front line anticancer drug, doxorubicin (DOX) onto DNA-capped gold nanoparticles whose duplex DNA has been designed for specific DOX intercalation. Since each AuNP contains about 108 high affinity drug sites, this design allows for a high local DOX concentration on the particle. Drug binding was confirmed by monitoring the increase in DNA melting temperature, the shift in the plasmon resonance maximum, and the increase in the NP hydrodynamic radius as a function of [DOX]/[DNA] ratio. The feasibility of the nanoparticles as a drug delivery system was demonstrated by showing that particle-bound DOX could be transferred to a target DNA.Type: GrantFiled: November 1, 2011Date of Patent: January 21, 2014Assignee: Syracuse UniversityInventors: Mathew Maye, James Dabrowiak, Colleen Alexander
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Patent number: 8487084Abstract: In some embodiments, DNA-capped nanoparticles are used to define a degree of crystalline order in assemblies thereof. In some embodiments, thermodynamically reversible and stable body-centered cubic (bcc) structures, with particles occupying <˜10% of the unit cell, are formed. Designs and pathways amenable to the crystallization of particle assemblies are identified. In some embodiments, a plasmonic crystal is provided. In some aspects, a method for controlling the properties of particle assemblages is provided. In some embodiments a catalyst is formed from nanoparticles linked by nucleic acid sequences and forming an open crystal structure with catalytically active agents attached to the crystal on its surface or in interstices.Type: GrantFiled: April 3, 2009Date of Patent: July 16, 2013Assignee: Brookhaven Science Associates, LLCInventors: Oleg Gang, Dmytro Nykypanchuk, Mathew Maye, Daniel van der Lelie
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Publication number: 20120141550Abstract: System and method for loading the front line anticancer drug, doxorubicin (DOX) onto DNA-capped gold nanoparticles whose duplex DNA has been designed for specific DOX intercalation. Since each AuNP contains about 108 high affinity drug sites, this design allows for a high local DOX concentration on the particle. Drug binding was confirmed by monitoring the increase in DNA melting temperature, the shift in the plasmon resonance maximum, and the increase in the NP hydrodynamic radius as a function of [DOX]/[DNA] ratio. The feasibility of the nanoparticles as a drug delivery system was demonstrated by showing that particle-bound DOX could be transferred to a target DNA.Type: ApplicationFiled: November 1, 2011Publication date: June 7, 2012Applicant: SYRACUSE UNIVERSITYInventors: Mathew Maye, James Dabrowiak, Colleen Alexander
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Publication number: 20120114962Abstract: A system and method to tailor the optical properties of nanomaterials using a core-alloy-shell nano-ultrastructure. Atomic diffusion is used at the nanoscale in order to process as-synthesized nanomaterials into core-alloy-shell architectures. The alloy formation is controlled by the deposition of the alloy solute atoms, and then by alloy interdiffusion of the solute into the core nanoparticle. By controlling temperature, it is possible to control how far the solute diffuses into the core, which in turn allows the tailoring of the optical response of the particle itself. The alloy formation and subsequent interdiffusion allows tailoring of the nanoparticle composition and ultrastructure, resulting in a dramatic tunability of the metal nanostructures surface plasmon response.Type: ApplicationFiled: November 8, 2011Publication date: May 10, 2012Applicant: SYRACUSE UNIVERSITYInventors: Mathew Maye, Peter Njoki, Wenjie Wu, Hyunjoo Han
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Publication number: 20120103789Abstract: The synthesis of energy and sensor relevant nanomaterials that involves the colloidal synthesis of quantum dots (e.g. CdSe, CdS, ZnS, CdSe/ZnS) under well-controlled hydrothermal conditions (100-200 degrees C.) using simple inorganic precursors. The resulting nanomaterials are of high quality, and are easily processed depending upon application, and their synthesis is scalable. Scalability is provided by the use of a synthetic microwave reactor, which employs dielectric heating for the rapid and controllable heating.Type: ApplicationFiled: October 28, 2011Publication date: May 3, 2012Applicant: SYRACUSE UNIVERSITYInventor: Mathew Maye
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Publication number: 20090275465Abstract: In some embodiments, DNA-capped nanoparticles are used to define a degree of crystalline order in assemblies thereof. In some embodiments, thermodynamically reversible and stable body-centered cubic (bcc) structures, with particles occupying <˜10% of the unit cell, are formed. Designs and pathways amenable to the crystallization of particle assemblies are identified. In some embodiments, a plasmonic crystal is provided. In some aspects, a method for controlling the properties of particle assemblages is provided. In some embodiments a catalyst is formed from nanoparticles linked by nucleic acid sequences and forming an open crystal structure with catalytically active agents attached to the crystal on its surface or in interstices.Type: ApplicationFiled: April 3, 2009Publication date: November 5, 2009Applicant: Brookhaven Science Associates, LLCInventors: Oleg Gang, Dmytro Nykypanchuk, Mathew Maye, Daniel van der Lelie
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Publication number: 20060178260Abstract: A method is featured for fabricating Carbon-supported AuPt nanoparticle catalysts for fuel cells, and particularly fuel cells using methanol as the fuel. The method prepares AuPt-based fuel cell catalysts having a wide range of controllable Au:Pt ratios. The AuPt catalysis are supportable on both carbon black (C) and C/TiO2 support materials. These materials demonstrate electro-catalytic activity towards CO and methanol oxidation, and O2 reduction. The same catalyst material is useful in constructing both anodes and cathodes, and demonstrates bifunctional activity.Type: ApplicationFiled: February 4, 2005Publication date: August 10, 2006Inventors: Chuan-Jian Zhong, Jin Luo, Mathew Maye, Nancy Kariuki
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Publication number: 20050235776Abstract: The present teachings are directed toward single metal and alloy nanoparticles and synthesis methods for preparing single metal and alloy nanoparticles.Type: ApplicationFiled: September 17, 2004Publication date: October 27, 2005Inventors: Ting He, Chuan-Jian Zhong, Jin Luo, Mathew Maye, Li Han, Nancy Kariuki, Lingyan Wang