Patents by Inventor Mathias Karlsson
Mathias Karlsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230127798Abstract: The disclosure relates to multi-well plates having fluidic connections between neighboring wells that are useful to produce a cell culture substrate and compliant with American National Standards Institute of the Society for Laboratory Automation and Screening (ANSI/SLAS) microplate standardsType: ApplicationFiled: April 8, 2021Publication date: April 27, 2023Inventors: Johan PIHL, Mathias KARLSSON, Paul KARILA
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Publication number: 20210388302Abstract: The disclosure relates to multi-well plates having fluidic connections between neighboring wells that are useful to produce a cell culture substrate and compliant with American National Standards Institute of the Society for Laboratory Automation and Screening (ANSI/SLAS) microplate standards.Type: ApplicationFiled: October 9, 2019Publication date: December 16, 2021Inventors: Johan PIHL, Mathias KARLSSON, Paul KARILA
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Patent number: 9983199Abstract: The following invention relates to a device for visual detection of hemolysis in a whole blood sample from a pierceable container, said device comprising at least one visible detection compartment and a transfer passage connected to said visible detection compartment, said device further comprising means for passing through the container to the interior of said container for accessing the whole blood and permitting transfer of a volume of plasma from said sample to said detection compartment via said transfer passage, wherein said device further is arranged with a separation device for separating plasma from blood cells within said whole blood sample before said plasma reaches the detection compartment, said device further being arranged with means providing a capillary action for generating a capillary force urging said volume of plasma to be transferred through the separation device to said detection compartment.Type: GrantFiled: December 7, 2012Date of Patent: May 29, 2018Assignee: Hemcheck Sweden AktiebolagInventor: Mathias Karlsson
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Publication number: 20180066301Abstract: This invention relates to a testing system arrangement for assessing the level of a biochemical marker, comprising a disposable device (2) with a sample inlet (4) and a at least one visible detection compartment (5A, 5B), for detection of said bio-chemical marker, a mobile unit (8) including a digital camera arranged to capture a digital picture (60) of said at least one visible detection compartment (5A, 5B), software run on a processor for analysing said picture (60) to assess said level and means arranged to present the result (70) of said assessment in a display (8A) of or connected to, said mobile unit (8), wherein said disposable device (2) is arranged with at least one reference surface (12) having a predetermined colour setting that is known to said software to enable exact assessment of the colour within said detection compartment (5A, 5B) by the use of said reference surface (12) within said digital picture as a basis reference.Type: ApplicationFiled: November 1, 2017Publication date: March 8, 2018Inventors: Mathias Karlsson, Sofia Hiort Af Omaes, Hjalmar Didrikson
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Publication number: 20170183708Abstract: This invention relates to a testing system arrangement for assessing the level of a biochemical marker, comprising a disposable device (2) with a sample inlet (4) and a at least one visible detection compartment (5A, 5B), for detection of said bio-chemical marker, a mobile unit (8) including a digital camera arranged to capture a digital picture (60) of said at least one visible detection compartment (5A, 5B), software run on a processor for analysing said picture (60) to assess said level and means arranged to present the result (70) of said assessment in a display (8A) of or connected to, said mobile unit (8), wherein said disposable device (2) is arranged with at least one reference surface (12) having a predetermined colour setting that is known to said software to enable exact assessment of the colour within said detection compartment (5A, 5B) by the use of said reference surface (12) within said digital picture as a basis reference.Type: ApplicationFiled: March 7, 2017Publication date: June 29, 2017Inventors: Mathias Karlsson, Sofia Hiort Af Ornaes, Hjalmar Didrikson
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Patent number: 9228953Abstract: This invention relates to a testing system for assessing the level of a biochemical marker, comprising a disposable device (2) with a sample inlet (4) and a at least one visible detection compartment (5A, 5B), arranged with composition including a chemical means (Y) for direct detection of said biochemical marker, wherein said composition also includes an inhibitor (Z) arranged to first detection compartment (5A) being arranged to block the biochemical marker up to a certain concentration.Type: GrantFiled: November 22, 2012Date of Patent: January 5, 2016Assignee: Calmark Sweden ABInventors: Mathias Karlsson, Sofia Hiort Af Ornaes
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Patent number: 9045792Abstract: The present invention relates to a testing system for analyzing a risk of developing organ failure or presence of organ failure, said system comprising a disposable testing device arranged to receive a biological sample, which testing system is further arranged with means for measuring within said sample the total amount of at least a first biological marker in the form of an intracellular enzyme, and comprising means for analyzing the measured value of said intracellular enzyme, and based on the results thereof being arranged to communicate the risk of developing organ failure or presence of organ failure to an operator of said testing system. The present invention also relates to a method for analyzing a risk of developing organ failure, or analyzing presence of organ failure.Type: GrantFiled: September 14, 2011Date of Patent: June 2, 2015Assignee: Calmark Sweden ABInventors: Mathias Karlsson, Sofia Hiort af Ornäs
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Publication number: 20150127078Abstract: A method of determining hypoxia in fetal scalp blood sampled during labor including the determination of total lactate dehydrogenase (LDH) in plasma obtained from the sample. The method can include the additional determination of K, Mg, Ca, AST, ALT, lactate in the plasma and/or blood. Increased values of one or more of LDH, Mg, Ca, AST, ALT, lactate are indicative of hypoxia in the fetus. Also disclosed is the use of a plasma separation apparatus in the method.Type: ApplicationFiled: January 8, 2015Publication date: May 7, 2015Inventors: Mathias Karlsson, Sofia Hiort af Ornäs
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Patent number: 8945824Abstract: A method of determining hypoxia in fetal scalp blood sampled during labor comprises the determination of total lactate dehydrogenase (LDH) in plasma obtained from the sample. The method can comprise the additional determination of K, Mg, Ca, AST, ALT, lactate in the plasma and/or blood. Increased values of one or more of LDH, Mg, Ca, AST, ALT, lactate are indicative of hypoxia in the fetus. Also disclosed is the use of a plasma separation apparatus in the method.Type: GrantFiled: April 11, 2008Date of Patent: February 3, 2015Assignee: Calmark Sweden AktiebolagInventors: Mathias Karlsson, Sofia Hiort af Ornäs
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Publication number: 20140329262Abstract: This invention relates to a testing system for assessing the level of a biochemical marker, comprising a disposable device (2) with a sample inlet (4) and a at least one visible detection compartment (5A, 5B), arranged with composition including a chemical means (Y) for direct detection of said biochemical marker, wherein said composition also includes an inhibitor (Z) arranged to first detection compartment (5A) being arranged to block the biochemical marker up to a certain concentration.Type: ApplicationFiled: November 22, 2012Publication date: November 6, 2014Inventors: Mathias Karlsson, Sofia Hiort Af Ornäs
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Publication number: 20140329268Abstract: The following invention relates to a device for visual detection of hemolysis in a whole blood sample from a pierceable container, said device comprising at least one visible detection compartment and a transfer passage connected to said visible detection compartment, said device further comprising means for passing through the container to the interior of said container for accessing the whole blood and permitting transfer of a volume of plasma from said sample to said detection compartment via said transfer passage, wherein said device further is arranged with a separation device for separating plasma from blood cells within said whole blood sample before said plasma reaches the detection compartment, said device further being arranged with means providing a capillary action for generating a capillary force urging said volume of plasma to be transferred through the separation device to said detection compartment.Type: ApplicationFiled: December 7, 2012Publication date: November 6, 2014Applicant: HEMCHECK SWEDEN AKTIEBOLAGInventor: Mathias Karlsson
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Publication number: 20140315229Abstract: This invention relates to a testing system arrangement for assessing the level of a biochemical marker, comprising a disposable device (2) with a sample inlet (4) and a at least one visible detection compartment (5A, 5B), for detection of said bio-chemical marker, a mobile unit (8) including a digital camera arranged to capture a digital picture (60) of said at least one visible detection compartment (5A, 5B), software run on a processor for analysing said picture (60) to assess said level and means arranged to present the result (70) of said assessment in a display (8A) of or connected to, said mobile unit (8), wherein said disposable device (2) is arranged with at least one reference surface (12) having a predetermined colour setting that is known to said software to enable exact assessment of the colour within said detection compartment (5A, 5B) by the use of said reference surface (12) within said digital picture as a basis reference.Type: ApplicationFiled: November 22, 2012Publication date: October 23, 2014Applicant: Calmark Sweden ABInventors: Mathias Karlsson, Sofia Hiort Af Ornaes, Hjalmar Didrikson
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Patent number: 8846333Abstract: The present invention relates to a device for visual detection of hemolysis in a whole blood sample, comprising at least one visible detection compartment and a transfer passage connected to said visible detection compartment, said transfer passage being arranged to permit transfer of a volume of plasma from said sample to said detection compartment and wherein said transfer passage further is arranged with a separation device (4) for separating plasma from blood cells within said whole blood sample before said plasma reaches the detection compartment, wherein said device is arranged with subpressure means providing a subpressure inside said detection compartment for generating a force urging said volume of plasma to be transferred from said whole blood sample to said detection compartment through said transfer passage and via said separation device.Type: GrantFiled: June 10, 2011Date of Patent: September 30, 2014Assignee: Hemcheck Sweden ABInventor: Mathias Karlsson
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Publication number: 20130171678Abstract: The present invention relates to a testing system for analyzing a risk of developing organ failure or presence of organ failure, said system comprising a disposable testing device arranged to receive a biological sample, which testing system is further arranged with means for measuring within said sample the total amount of at least a first biological marker in the form of an intracellular enzyme, and comprising means for analyzing the measured value of said intracellular enzyme, and based on the results thereof being arranged to communicate the risk of developing organ failure or presence of organ failure to an operator of said testing system. The present invention also relates to a method for analyzing a risk of developing organ failure, or analyzing presence of organ failure.Type: ApplicationFiled: September 14, 2011Publication date: July 4, 2013Applicant: CALMARK SWEDEN ABInventors: Mathias Karlsson, Sofia Hiort af Ornäs
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Publication number: 20130052675Abstract: The present invention relates to a testing system for assessing hypoxia induced cellular damage in a mammal including human, comprising a disposable device having a sample inlet and a collection chamber separated by a separation device wherein the collection chamber is connected to at least two, a first and a second, visible detection compartments, whereof at least one is arranged with chemical means for direct visual detection, said first detection compartment being arranged to determine whether level of hemoglobin (Hb) in a sample of body fluid taken from said mammal exceeds a predetermined threshold value, and said second detection compartment being arranged to evaluate level of total amount of lactate dehydrogenase (LDH) in said sample.Type: ApplicationFiled: September 30, 2010Publication date: February 28, 2013Applicant: CALMARK SWEDEN AKTIEBOLAGInventors: Mathias Karlsson, Sofia Hiort af Ornäs
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Publication number: 20130040333Abstract: The present invention relates to a device for visual detection of hemolysis in a whole blood sample, comprising at least one visible detection compartment and a transfer passage connected to said visible detection compartment, said transfer passage being arranged to permit transfer of a volume of plasma from said sample to said detection compartment and wherein said transfer passage further is arranged with a separation device (4) for separating plasma from blood cells within said whole blood sample before said plasma reaches the detection compartment, wherein said device is arranged with subpressure means providing a subpressure inside said detection compartment for generating a force urging said volume of plasma to be transferred from said whole blood sample to said detection compartment through said transfer passage and via said separation device.Type: ApplicationFiled: June 10, 2011Publication date: February 14, 2013Applicant: HEMCHECK SWEDEN AKTIEBOLAGInventor: Mathias Karlsson
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Publication number: 20080213744Abstract: A method of determining hypoxia in fetal scalp blood sampled during labor comprises the determination of total lactate dehydrogenase (LDH) in plasma obtained from the sample. The method can comprise the additional determination of K, Mg, Ca, AST, ALT, lactate in the plasma and/or blood. Increased values of one or more of LDH, Mg, Ca, AST, ALT, lactate are indicative of hypoxia in the fetus. Also disclosed is the use of a plasma separation apparatus in the method.Type: ApplicationFiled: April 11, 2008Publication date: September 4, 2008Inventors: Mathias Karlsson, Sofia Hirot af Ornas
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Patent number: D694889Type: GrantFiled: March 14, 2013Date of Patent: December 3, 2013Assignee: Calmark Sweden ABInventors: Mathias Karlsson, Sofia Hiort Af Ornas, Victoria Hultdin
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Patent number: D725284Type: GrantFiled: October 11, 2013Date of Patent: March 24, 2015Assignee: Hemcheck Sweden AktiebolagInventors: Mathias Karlsson, Annelie Brolinson, Pekka Niskala