Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object, the method comprising: generating an initial X-ray projection image of an object with an imaging beam produced by an imaging system; based on a first transmission indicator for the object and on a second transmission indicator for at least one element of the imaging system, selecting a kernel for convolution of the initial projection image; convolving the initial X-ray projection image with the kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object comprises: generating an initial X-ray projection image with an imaging beam and an X-ray detector; based on a first position in a detector array of the X-ray detector, selecting a first kernel for convolution of a first portion of the initial projection image, wherein the first position corresponds to the first portion of the initial projection image; based on a second position in the detector array of the X-ray detector, selecting a second kernel for convolution of a second portion of the initial projection image, wherein the second position corresponds to the second portion of the initial projection image; convolving the first portion with the first kernel and the second portion with the second kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A computer-implemented method for modifying X-ray projection images of a subject region includes: generating a set of combined two-dimensional (2D) projections of a subject region, wherein each combined 2D projection includes one or more mask-bordering pixels and one or more mask-edge pixels; forming a three-dimensional (3D) matrix of the set of combined 2D projections; based on the 3D matrix, generating a linear algebraic system for determining pixel values for pixels indicated in a set of 2D projection metal masks, wherein a first change in slope of pixel value associated with a mask-edge pixel of a combined 2D projection is constrained to equal a second change in slope of pixel value associated with a mask-bordering pixel of a combined 2D projection; determining values for a variable vector of the linear algebraic system; and generating a set of inpainted 2D projections by modifying initial 2D projections with values for the variable vector.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object comprises: generating an initial X-ray projection image with an imaging beam and an X-ray detector; based on a first position in a detector array of the X-ray detector, selecting a first kernel for convolution of a first portion of the initial projection image, wherein the first position corresponds to the first portion of the initial projection image; based on a second position in the detector array of the X-ray detector, selecting a second kernel for convolution of a second portion of the initial projection image, wherein the second position corresponds to the second portion of the initial projection image; convolving the first portion with the first kernel and the second portion with the second kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: Systems and methods for determining beam asymmetry in a radiation treatment system using electronic portal imaging devices (EPIDs) without implementation of elaborate and complex EPID calibration procedures. The beam asymmetry is determined based on radiation scattered from different points in the radiation beam and measured with the same region of interest ROI of the EPID.

Abstract: A computer-implemented method for modifying X-ray projection images of a subject region includes: generating a set of combined two-dimensional (2D) projections of a subject region, wherein each combined 2D projection includes one or more mask-bordering pixels and one or more mask-edge pixels; forming a three-dimensional (3D) matrix of the set of combined 2D projections; based on the 3D matrix, generating a linear algebraic system for determining pixel values for pixels indicated in a set of 2D projection metal masks, wherein a first change in slope of pixel value associated with a mask-edge pixel of a combined 2D projection is constrained to equal a second change in slope of pixel value associated with a mask-bordering pixel of a combined 2D projection; determining values for a variable vector of the linear algebraic system; and generating a set of inpainted 2D projections by modifying initial 2D projections with values for the variable vector.

Abstract: A computer-implemented method of segmenting a reconstructed volume of a region of patient anatomy includes: determining an anatomical region associated with the reconstructed volume; detecting one or more metal objects disposed in an initial 3D metal object mask associated with the reconstructed volume; for each of the one or more metal objects disposed in the initial 3D metal object mask, determining a volume associated with the metal object; determining a value for at least one segmentation parameter based on the anatomical region and on the volume associated with the one or more metal objects; and generating a final 3D metal object mask associated with the reconstructed digital volume using the value for the segmentation parameter.

Abstract: Systems and methods for using electronic portal imaging devices (EPIDs) as absolute radiation beam measuring devices and as radiation beam alignment devices without implementation of elaborate and complex calibration procedures.

Abstract: A cone-beam computed tomography (CBCT) method uses a continuous beam and an area detector to carry out fast acquisition of projection data. The acquired projection data are then reconstructed to generate tomographic images. In acquisition of the projection data, a radiation source continuously irradiates a subject with a cone beam of radiation from a plurality of angles and an area detector continuously reads out data. A CBCT system including a source operable to produce a cone beam of radiation and an area detector movable in synchrony with the source to rapidly acquire projection data for CBCT construction is also disclosed.

Abstract: An image acquisition apparatus includes: a positioner controller communicatively coupled to a positioner, wherein the positioner controller is configured to generate a control signal to cause the positioner to rectilinearly translate a patient support relative to an imager, and/or to rectilinearly translate the imager relative to the patient support; an imaging controller configured to operate the imager to generate a first plurality of two-dimensional images for a patient while the patient is supported by the patient support, and while the positioner rectilinearly translates the patient support and/or the imager; and an image processing unit configured to obtain the first plurality of two-dimensional images and arrange the two-dimensional images relative to each other to obtain a first composite image.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object comprises: generating an initial X-ray projection image with an imaging beam and an X-ray detector; based on a first position in a detector array of the X-ray detector, selecting a first kernel for convolution of a first portion of the initial projection image, wherein the first position corresponds to the first portion of the initial projection image; based on a second position in the detector array of the X-ray detector, selecting a second kernel for convolution of a second portion of the initial projection image, wherein the second position corresponds to the second portion of the initial projection image; convolving the first portion with the first kernel and the second portion with the second kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object, the method comprising: generating an initial X-ray projection image of an object with an imaging beam produced by an imaging system; based on a first transmission indicator for the object and on a second transmission indicator for at least one element of the imaging system, selecting a kernel for convolution of the initial projection image; convolving the initial X-ray projection image with the kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A computer-implemented method of determining X-ray dose delivered to a region of patient anatomy includes: using a first imaging condition, generating a set of projection images of a region of patient anatomy; based on the set of projection images of the target volume, reconstructing a digital volume that includes a target volume disposed within the region of patient anatomy; based on the digital volume, determine current position of the target volume within the region of patient anatomy; delivering a treatment beam to the target volume while disposed at the current position; based on the first imaging condition, selecting a first calibration curve from a plurality of calibration curves, wherein each calibration curve in the plurality of calibration curves is associated with a different imaging condition; and based on the first calibration curve, determining an x-ray dose delivered to a portion of the target volume.

Abstract: An image acquisition apparatus includes: a positioner controller communicatively coupled to a positioner, wherein the positioner controller is configured to generate a control signal to cause the positioner to rectilinearly translate a patient support relative to an imager, and/or to rectilinearly translate the imager relative to the patient support; an imaging controller configured to operate the imager to generate a first plurality of two-dimensional images for a patient while the patient is supported by the patient support, and while the positioner rectilinearly translates the patient support and/or the imager; and an image processing unit configured to obtain the first plurality of two-dimensional images and arrange the two-dimensional images relative to each other to obtain a first composite image.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object, the method comprising: generating an initial X-ray projection image of an object with an imaging beam produced by an imaging system; based on a first transmission indicator for the object and on a second transmission indicator for at least one element of the imaging system, selecting a kernel for convolution of the initial projection image; convolving the initial X-ray projection image with the kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object comprises: generating an initial X-ray projection image with an imaging beam and an X-ray detector; based on a first position in a detector array of the X-ray detector, selecting a first kernel for convolution of a first portion of the initial projection image, wherein the first position corresponds to the first portion of the initial projection image; based on a second position in the detector array of the X-ray detector, selecting a second kernel for convolution of a second portion of the initial projection image, wherein the second position corresponds to the second portion of the initial projection image; convolving the first portion with the first kernel and the second portion with the second kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: Systems and methods for determining beam asymmetry in a radiation treatment system using electronic portal imaging devices (EPIDs) without implementation of elaborate and complex EPID calibration procedures. The beam asymmetry is determined based on radiation scattered from different points in the radiation beam and measured with the same region of interest ROI of the EPID.

Abstract: Systems and methods for determining beam asymmetry in a radiation treatment system using electronic portal imaging devices (EPIDs) without implementation of elaborate and complex EPID calibration procedures. The beam asymmetry is determined based on radiation scattered from different points in the radiation beam and measured with the same region of interest ROI of the EPID.

Abstract: A computer-implemented method of segmenting a reconstructed volume of a region of patient anatomy includes: determining an anatomical region associated with the reconstructed volume; detecting one or more metal objects disposed in an initial 3D metal object mask associated with the reconstructed volume; for each of the one or more metal objects disposed in the initial 3D metal object mask, determining a volume associated with the metal object; determining a value for at least one segmentation parameter based on the anatomical region and on the volume associated with the one or more metal objects; and generating a final 3D metal object mask associated with the reconstructed digital volume using the value for the segmentation parameter.

Abstract: A computer-implemented method for modifying X-ray projection images of a subject region includes: generating a set of combined two-dimensional (2D) projections of a subject region, wherein each combined 2D projection includes one or more mask-bordering pixels and one or more mask-edge pixels; forming a three-dimensional (3D) matrix of the set of combined 2D projections; based on the 3D matrix, generating a linear algebraic system for determining pixel values for pixels indicated in a set of 2D projection metal masks, wherein a first change in slope of pixel value associated with a mask-edge pixel of a combined 2D projection is constrained to equal a second change in slope of pixel value associated with a mask-bordering pixel of a combined 2D projection; determining values for a variable vector of the linear algebraic system; and generating a set of inpainted 2D projections by modifying initial 2D projections with values for the variable vector.