Abstract: The present invention is related to agents capable of binding to and inhibiting or antagonizing the action of IL-11 and/or or IL-11RA for the treatment and/or prevention of abnormal uterine bleeding, which comprises heavy menstrual bleeding, prolonged bleeding, altered bleeding pattern, dysmenorrhea, as well as of the underlying diseases leiomyoma and endometriosis and the use of the agent to inhibit menstruation. Furthermore, the invention provides novel IL-11 antibodies.

Abstract: A method for producing a connection between component parts and a component made of component parts are disclosed. In an embodiment, a includes providing a first component part having a first exposed insulation layer and a second component part having a second exposed insulation layer, wherein each of the insulation layers has at least one opening, joining together the first and second component parts such that the opening of the first insulation layer and the opening of the second insulation layer overlap in top view, wherein an Au layer and a Sn layer are arranged one above the other in at least one of the openings and melting the Au layer and the Sn layer to form an AuSn alloy, wherein the AuSn alloy forms a through-via after cooling electrically conductively connecting the first component part to the second component part.

Abstract: At least one fiber-optic sensor unit measures a mechanical variable which affects a rail having a certain length and a neutral axis that extends along said length of the rail. The at least one fiber-optic sensor unit is disposed at an angle of 30° to 60°, in particular 45°, relative to the neutral axis or at an angle of ?30° to ?60°, in particular ?45°, relative to the neutral axis. The at least one fiber-optic sensor unit is irradiated with primary light in order to generate a signaling light in a reflection mode or transmission mode. The intensity of the signaling light is sensed. The signaling light is evaluated.

Abstract: A transmission includes a housing, having lower and upper housing parts and bearing seats. A web is formed on the lower housing part between two bearing seats, which is pressed against a web provided on the upper housing part and between the bearing seats. When the housing parts are separated or pulled apart, a first web of one of the housing parts projects beyond a planar surface, which restricts the other webs thereof, or the webs of one of the housing parts are restricted by a planar separating surface, and except for a first web, the webs of the other housing part are also restricted by the planar separating surface and the first web projects beyond the separating surface when the housing parts are separated from each other. To form the housing, at least one of the housing parts is elastically deformed and/or preloaded.

Abstract: A transmission includes a housing, having lower and upper housing parts and bearing seats. A web is formed on the lower housing part between two bearing seats, which is pressed against a web provided on the upper housing part and between the bearing seats. When the housing parts are separated or pulled apart, a first web of one of the housing parts projects beyond a planar surface, which restricts the other webs thereof, or the webs of one of the housing parts are restricted by a planar separating surface, and except for a first web, the webs of the other housing part are also restricted by the planar separating surface and the first web projects beyond the separating surface when the housing parts are separated from each other. To form the housing, at least one of the housing parts is elastically deformed and/or preloaded.

Abstract: A transmission includes a housing, having lower and upper housing parts, and having bearing seats. A web is formed on the lower housing part between two bearing seats in each case, which is pressed against a web provided on the upper housing part and between the respective bearing seats.

Abstract: The invention relates to an acoustic emission sensor (100). The acoustic emission sensor comprises an optical resonator (10) having a sensor region (11) configured for reflective operation; an optical waveguide (20) which is optically coupled to the optical resonator (10); a light source (31) which is optically coupled to the optical waveguide (20) to apply light to the optical waveguide (20); and a detection device (32) which is optically coupled to the optical waveguide (20) to detect light from the optical resonator (10). The sensor region (11) of the optical resonator (10) comprises a coupling device (50) for mechanically coupling to a solid measurement object (200). The coupling device (50) comprises a first coupling element (51) for transmitting an acoustic emission signal between the sensor region (11) and the solid measurement object (200), and at least one second coupling element (52).

Abstract: A scan unit (100)—e.g., for Light Detection and Ranging, LIDAR—comprises a base (141) and a minor (150) for deflecting light (180). A first set (600) includes at least three torsion springs (601-605) extending along an axis (z, 119) between the base (141) and the mirror (150) in a first plane (691). A second set (610) includes at least three torsion springs (611-613) extending along the axis (z, 119) between the base (141) and the mirror (150) in a second plane (692) that is offset and parallel to the first plane (691).

Abstract: A method of mass spectrometry is provided. The method comprises eluting a sample from a chromatography system, and calculating a desired maximum scan duration for the sample eluting from the chromatographic system based on a duration of a chromatographic peak of the sample as it elutes from the chromatography system, and a minimum number of scans per chromatographic peak to be performed. A maximum accumulation duration is calculated based on the desired maximum scan duration. The sample is ionised to produce sample ions using an ion source. The sample ions are directed along an ion path from the ion source to a mass analyser. A first set of mass analysis scans are performed. Each of the first set of mass analysis scans comprises: accumulating a portion of sample ions at a point along the ion path, wherein the portion of sample ions are accumulated for a duration not exceeding the maximum accumulation duration, and mass analysing the portion of sample ions using the mass analyser.

Abstract: An energy supply device for supplying electric power to a consumer of a vehicle has an input for establishing a connection to an on-board network of the vehicle in order to provide an input voltage for a transmission arrangement, an output for outputting a supply voltage to operate the consumer, a transmission arrangement for purposes of transmitting electric energy between the input and the output, whereby the transmission arrangement comprises a signaling adaptation means, so that, as a function of a deviation of the input voltage that is critical for the electric power supply, a signal is impressed upon the supply voltage, whereby the signal can be evaluated in the consumer on the basis of the supply voltage.

Abstract: A transmission includes a housing, having lower and upper housing parts, and having bearing seats. A web is formed on the lower housing part between two bearing seats in each case, which is pressed against a web provided on the upper housing part and between the respective bearing seats.

Abstract: A vehicle roof having at least one transparent section, a roof-attached support section and a roller blind assembly for selectively shading the transparent roof section at least partially. The blind assembly including at least one roller blind unit having a web to be wound up to form a reel and one lateral bearing unit on either side of a vertical longitudinal roof center plane. The reel disposed between two lateral bearing units and the roller blind assembly having a bearing shell on top of which the at least one roller blind unit is fastened via the lateral bearing units which is fixed to the at least one support section from below. Each bearing units has a bearing pedestal fixed to the bearing shell and a roller blind guide element displaceable as against the bearing pedestal in a pre-installation position and fixed to the roof-attached support section in an installation position.

Abstract: A vehicle roof having at least one transparent roof portion, a roof-attached support portion and a roller blind assembly for selectively shading or at least partially exposing the transparent roof portion, the roller blind assembly having at least one roller blind unit comprising a roller blind web, which can be wound up into a roller blind coil, and a lateral bearing element on either side of the vertical longitudinal center plane of the roof. The roller blind coil can be disposed between the two lateral bearing elements. The roller blind assembly may have a bearing shell on top of which the at least one roller blind unit is attached via the lateral bearing elements and which is fixed to the at least one support portion from below.

Abstract: A vehicle roof having at least one transparent section, a roof-attached support section and a roller blind assembly for selectively shading the transparent roof section at least partially. The blind assembly including at least one roller blind unit having a web to be wound up to form a reel and one lateral bearing unit on either side of a vertical longitudinal roof center plane. The reel disposed between two lateral bearing units and the roller blind assembly having a bearing shell on top of which the at least one roller blind unit is fastened via the lateral bearing units which is fixed to the at least one support section from below. Each bearing units has a bearing pedestal fixed to the bearing shell and a roller blind guide element displaceable as against the bearing pedestal in a pre-installation position and fixed to the roof-attached support section in an installation position.

Abstract: Embodiments of the invention describe a method for ascertaining a value of an ice buildup quantity on at least one rotor blade (111, 112) of a wind turbine (100) and to the use thereof.

Abstract: A method of mass spectrometry is provided. The method comprises eluting a sample from a chromatography system, and calculating a desired maximum scan duration for the sample eluting from the chromatographic system based on a duration of a chromatographic peak of the sample as it elutes from the chromatography system, and a minimum number of scans per chromatographic peak to be performed. A maximum accumulation duration is calculated based on the desired maximum scan duration. The sample is ionised to produce sample ions using an ion source. The sample ions are directed along an ion path from the ion source to a mass analyser. A first set of mass analysis scans are performed. Each of the first set of mass analysis scans comprises: accumulating a portion of sample ions at a point along the ion path, wherein the portion of sample ions are accumulated for a duration not exceeding the maximum accumulation duration, and mass analysing the portion of sample ions using the mass analyser.

Abstract: There is provided a fiber-optic pressure sensor (110), which includes a waveguide (112) having an end, an optical deflection unit (301) connected to the end of the waveguide (112), and a sensor body (300) at which an optical resonator (302) is formed by way of a diaphragm (303). The waveguide (112) and/or the deflection unit (301) is/are attached to the sensor body (300) by way of a curable adhesive or a solder connection.

Abstract: The invention relates to an acoustic emission sensor (100). The acoustic emission sensor comprises an optical resonator (10) having a sensor region (11) configured for reflective operation; an optical waveguide (20) which is optically coupled to the optical resonator (10); a light source (31) which is optically coupled to the optical waveguide (20) to apply light to the optical waveguide (20); and a detection device (32) which is optically coupled to the optical waveguide (20) to detect light from the optical resonator (10). The sensor region (11) of the optical resonator (10) comprises a coupling device (50) for mechanically coupling to a solid measurement object (200). The coupling device (50) comprises a first coupling element (51) for transmitting an acoustic emission signal between the sensor region (11) and the solid measurement object (200), and at least one second coupling element (52).

Abstract: A clamping device (300) for a light guide (112) is provided. The clamping device (300) includes a carrier structure having a first securing element (301) for securing the light guide (112) in a first position (401), and a second securing element (302) at a distance from the first securing element (301) for securing the light guide (112) in a second position (402), wherein the first and second positions (401, 402) have a first distance (403) in a longitudinal extension of the light guide (112). Further, an intermediate carrier (500) having a first surface (503) on which the first and second securing elements (301, 302) are attached in respective securing positions (501, 502), and an opposing second surface (504), which can be applied to a measurement object, is provided. Hereby, a second distance (505) of the securing positions (501, 502) of the securing elements (301, 302) on the intermediate carrier (500) is greater than the first distance (403) in a longitudinal direction of the light guide (112).

Abstract: Embodiments describe a method for predicting the accumulation of ice on a rotor blade (111, 112) of a wind turbine (100) and the use thereof.