Abstract: At least one fiber-optic sensor unit measures a mechanical variable which affects a rail having a certain length and a neutral axis that extends along said length of the rail. The at least one fiber-optic sensor unit is disposed at an angle of 30° to 60°, in particular 45°, relative to the neutral axis or at an angle of ?30° to ?60°, in particular ?45°, relative to the neutral axis. The at least one fiber-optic sensor unit is irradiated with primary light in order to generate a signaling light in a reflection mode or transmission mode. The intensity of the signaling light is sensed. The signaling light is evaluated.

Abstract: A method of mass spectrometry is provided. The method comprises eluting a sample from a chromatography system, and calculating a desired maximum scan duration for the sample eluting from the chromatographic system based on a duration of a chromatographic peak of the sample as it elutes from the chromatography system, and a minimum number of scans per chromatographic peak to be performed. A maximum accumulation duration is calculated based on the desired maximum scan duration. The sample is ionised to produce sample ions using an ion source. The sample ions are directed along an ion path from the ion source to a mass analyser. A first set of mass analysis scans are performed. Each of the first set of mass analysis scans comprises: accumulating a portion of sample ions at a point along the ion path, wherein the portion of sample ions are accumulated for a duration not exceeding the maximum accumulation duration, and mass analysing the portion of sample ions using the mass analyser.

Abstract: A vehicle roof having at least one transparent section, a roof-attached support section and a roller blind assembly for selectively shading the transparent roof section at least partially. The blind assembly including at least one roller blind unit having a web to be wound up to form a reel and one lateral bearing unit on either side of a vertical longitudinal roof center plane. The reel disposed between two lateral bearing units and the roller blind assembly having a bearing shell on top of which the at least one roller blind unit is fastened via the lateral bearing units which is fixed to the at least one support section from below. Each bearing units has a bearing pedestal fixed to the bearing shell and a roller blind guide element displaceable as against the bearing pedestal in a pre-installation position and fixed to the roof-attached support section in an installation position.

Abstract: A vehicle roof having at least one transparent roof portion, a roof-attached support portion and a roller blind assembly for selectively shading or at least partially exposing the transparent roof portion, the roller blind assembly having at least one roller blind unit comprising a roller blind web, which can be wound up into a roller blind coil, and a lateral bearing element on either side of the vertical longitudinal center plane of the roof. The roller blind coil can be disposed between the two lateral bearing elements. The roller blind assembly may have a bearing shell on top of which the at least one roller blind unit is attached via the lateral bearing elements and which is fixed to the at least one support portion from below.

Abstract: A vehicle roof having at least one transparent section, a roof-attached support section and a roller blind assembly for selectively shading the transparent roof section at least partially. The blind assembly including at least one roller blind unit having a web to be wound up to form a reel and one lateral bearing unit on either side of a vertical longitudinal roof center plane. The reel disposed between two lateral bearing units and the roller blind assembly having a bearing shell on top of which the at least one roller blind unit is fastened via the lateral bearing units which is fixed to the at least one support section from below. Each bearing units has a bearing pedestal fixed to the bearing shell and a roller blind guide element displaceable as against the bearing pedestal in a pre-installation position and fixed to the roof-attached support section in an installation position.

Abstract: A method of mass spectrometry is provided. The method comprises eluting a sample from a chromatography system, and calculating a desired maximum scan duration for the sample eluting from the chromatographic system based on a duration of a chromatographic peak of the sample as it elutes from the chromatography system, and a minimum number of scans per chromatographic peak to be performed. A maximum accumulation duration is calculated based on the desired maximum scan duration. The sample is ionised to produce sample ions using an ion source. The sample ions are directed along an ion path from the ion source to a mass analyser. A first set of mass analysis scans are performed. Each of the first set of mass analysis scans comprises: accumulating a portion of sample ions at a point along the ion path, wherein the portion of sample ions are accumulated for a duration not exceeding the maximum accumulation duration, and mass analysing the portion of sample ions using the mass analyser.

Abstract: A scanner (90) comprises a first mirror (150) having a reflective front side (151) and a rear side (152), a first elastic mounting (100) which extends on a side facing the rear side (152) of the first mirror (150), a second mirror (150) having a reflective front side (151) and a rear side (152), and a second elastic mounting (100) which extends on a side facing the rear side (152) of the second mirror (150). The scanner (90) is configured to deflect light (180) sequentially at the front side (151) of the first mirror (150) and at the front side (151) of the second mirror (150).

Abstract: A vehicle roof having at least one transparent roof portion, a roof-attached support portion and a roller blind assembly for selectively shading or at least partially exposing the transparent roof portion, the roller blind assembly having at least one roller blind unit comprising a roller blind web, which can be wound up into a roller blind coil, and a lateral bearing element on either side of the vertical longitudinal center plane of the roof. The roller blind coil can be disposed between the two lateral bearing elements. The roller blind assembly may have a bearing shell on top of which the at least one roller blind unit is attached via the lateral bearing elements and which is fixed to the at least one support portion from below.

Abstract: At least one fiber-optic sensor unit measures a mechanical variable which affects a rail having a certain length and a neutral axis that extends along said length of the rail. The at least one fiber-optic sensor unit is disposed at an angle of 30° to 60°, in particular 45°, relative to the neutral axis or at an angle of ?30° to ?60°, in particular ?45°, relative to the neutral axis. The at least one fiber-optic sensor unit is irradiated with primary light in order to generate a signaling light in a reflection mode or transmission mode. The intensity of the signaling light is sensed. The signaling light is evaluated.

Abstract: An axle-counting method for railbound vehicles includes the following method steps: coupling light into at least one sensor fiber, wherein the sensor fiber includes at least one fiber Bragg grating mounted on a rail, wherein each fiber Bragg grating has a reflection spectrum having a reflection peak which is at a Bragg wavelength and has a full width at half maximum; generating a difference signal from two shear stress signals through detection and filtering the temporal intensity course of the light power reflected by two Fiber Bragg gratings which are arranged at a separation from one another; and generating a wheel signal if the difference signal exceeds a predetermined shear stress difference limiting value.

Abstract: An axle-counting method for railbound vehicles includes the following method steps: coupling light into at least one sensor fiber, wherein the sensor fiber includes at least one fiber Bragg grating mounted on a rail, wherein each fiber Bragg grating has a reflection spectrum having a reflection peak which is at a Bragg wavelength and has a full width at half maximum; generating a difference signal from two shear stress signals through detection and filtering the temporal intensity course of the light power reflected by two Fiber Bragg gratings which are arranged at a separation from one another; and generating a wheel signal if the difference signal exceeds a predetermined shear stress difference limiting value.

Abstract: At least one fiber-optic sensor unit measures a mechanical variable which affects a rail having a certain length and a neutral axis that extends along said length of the rail. The at least one fiber-optic sensor unit is disposed at an angle of 30° to 60°, in particular 45°, relative to the neutral axis or at an angle of ?30° to ?60°, in particular ?45°, relative to the neutral axis. The at least one fiber-optic sensor unit is irradiated with primary light in order to generate a signaling light in a reflection mode or transmission mode. The intensity of the signaling light is sensed. The signaling light is evaluated.

Abstract: The present invention relates to a novel microRNA, mir-208-2, implicated in muscular and cardiovascular disorders. The present invention also relates to oligonucleotide therapeutic agents (antisense oligonucleotides and/or double stranded oligonucleotides such as dsRNA) and their use in the treatment of muscular and cardiovascular disorders resulting from dysregulation of mir-208-2.

Abstract: A force-moment sensor is provided for measuring at least one force and/or moment, which comprises a first part, a second part and an optical fibre arranged therebetween, said optical fibre comprising in at least one section a component for detecting deformations and/or stresses of the fibre transversely to its longitudinal axis. The present invention further relates to a method for measuring forces and/or moments. Thus, a fibre is provided which comprises at least one component for detecting deformations and/or stresses of the fibre transversely to a longitudinal axis of the fibre and into which light is introduced. According to this method, a force and/or moment acts on the fibre, wherein at least one component of the force and/or moment acts perpendicularly to the longitudinal axis of the fibre. The light reflected in the fibre is then detected and the detected spectrum analysed.

Abstract: An expandable reamer apparatus and methods for reaming a borehole are disclosed, including at least one laterally movable blade carried by a tubular body selectively positioned at an inward position and an expanded position. The at least one laterally movable blade, held inwardly by at least one blade-biasing element, may be forced outwardly by drilling fluid selectively allowed to communicate therewith or by at least one intermediate piston element. For example, an actuation sleeve may allow communication of drilling fluid with the at least one laterally movable blade in response to an actuation device being deployed within the drilling fluid. Alternatively, a chamber in communication with an intermediate piston element in structural communication with the at least one laterally movable blade may be pressurized by way of a movable sleeve, a downhole turbine, or a pump.

Abstract: An expandable reamer apparatus and methods for reaming a borehole are disclosed, including at least one laterally movable blade carried by a tubular body selectively positioned at an inward position and an expanded position. The at least one movable blade, held inwardly by at least one blade-biasing element, may be forced outwardly by drilling fluid selectively allowed to communicate therewith or by at least one intermediate piston element. For example, an actuation sleeve may allow communication of drilling fluid with the at least one movable blade in response to an actuation device being deployed within the drilling fluid. Alternatively, a chamber in communication with an intermediate piston element in structural communication with the movable blade may be pressurized by way of a movable sleeve, a downhole turbine, or a pump.

Abstract: Two-component epoxide resin compositions are described in which the epoxy component A contains at least one epoxide resin with an epoxy functionality greater than 1 and as second component B there is used a liquid or pasty hardener component containing amines, polyetheramines, polyaminoamides, Mannich bases and/or compounds containing mercapto groups, which additionally contains a non-volatile and non-corrosive accelerator. These adhesives can be used in automobile carcass assembly as well as in general automobile construction, whereby a rapid handling time is achieved and warping in structural parts is avoided.