Patents by Inventor Mathias SCHELWIES

Mathias SCHELWIES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11413610
    Abstract: The present invention relates to the use of a transition metal catalyst TMC1, which comprises a transition metal M selected from metals of groups 7, 8, 9 and 10 of the periodic table of elements according to IUPAC and a tetradentate ligand of formula I wherein R1 are identical or different and are each an organic radical having from 1 to 40 carbon atoms, and R2 are identical or different and are each an organic radical having from 1 to 40 carbon atoms, as catalyst in processes for formation of compounds comprising at least one carboxylic acid ester functional group —O—C(?O)— starting from at least one primary alcohol and/or hydrogenation of compounds comprising at least one carboxylic acid ester functional group —O—C(?O)—.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: August 16, 2022
    Assignee: BASF SE
    Inventors: Thomas Schaub, Aviel Anaby, Mathias Schelwies, Rocco Paciello, Jonas Schwaben, A. Stephen K. Hashmi
  • Publication number: 20220089559
    Abstract: The present invention relates to a process for carbonylating allyl alcohols at low temperature, low pressure and/or low catalyst loading. In an alternative embodiment, an acylation product of the allyl alcohol is used for the carbonylation. The present invention likewise relates to the preparation of conversion products of these carbonylation products and specifically of (?)-ambrox.
    Type: Application
    Filed: December 6, 2021
    Publication date: March 24, 2022
    Inventors: Mathias SCHELWIES, Rocco PACIELLO, Ralf PELZER, Wolfgang SIEGEL
  • Patent number: 11192873
    Abstract: The present invention relates to a process for carbonylating allyl alcohols at low temperature, low pressure and/or low catalyst loading. In an alternative embodiment, an acylation product of the allyl alcohol is used for the carbonylation. The present invention likewise relates to the preparation of conversion products of these carbonylation products and specifically of (?)-ambrox.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: December 7, 2021
    Assignee: BASF SE
    Inventors: Mathias Schelwies, Rocco Paciello, Ralf Pelzer, Wolfgang Siegel
  • Publication number: 20210371361
    Abstract: A reactor for performing a gas/liquid biphasic high-pressure reaction with a foaming medium, comprising an interior formed by a cylindrical, vertically oriented elongate shell, a bottom and a cap, wherein the interior is divided by internals into a backmixed zone and a zone of limited backmixing, wherein the backmixed zone and the zone of limited backmixing are consecutively traversable by the reaction mixture, wherein the backmixed zone comprises means for introducing gas and liquid and a gas outlet and also comprises at least one mixing apparatus selected from a stirrer, a jet nozzle and means for injecting the gas, and the zone of limited backmixing comprises a reaction product outlet, a first cylindrical internal element which in the interior extends in the longitudinal direction of the reactor and which delimits the zone of limited backmixing from the backmixed zone, backmixing-preventing second internal elements in the form of random packings, structured packings or liquid-permeable trays arranged in th
    Type: Application
    Filed: September 3, 2019
    Publication date: December 2, 2021
    Inventors: Oliver BEY, Peter ZEHNER, Michael ACKER, Rocco PACIELLO, Mathias SCHELWIES, Martin HAUBNER, Guenter WEGNER, Gerd TEBBEN, Gunnar HEYDRICH, Georg SEEBER
  • Publication number: 20210354101
    Abstract: A process for performing a continuous gas/liquid biphasic high-pressure reaction, wherein a gas and a liquid are introduced into a backmixed zone of a reactor and in the backmixed zone the gas is dispersed in the liquid by stirring, injection of gas and/or a liquid jet, a reaction mixture consecutively traverses the backmixed zone and a zone of limited backmixing, and a liquid reaction product is withdrawn at a reaction product outlet of the zone of limited backmixing, wherein the reactor comprises: an interior formed by a cylindrical vertically oriented elongate shell, a bottom and a cap, wherein the interior is divided by means of internals into the backmixed zone, the zone of limited backmixing and a cavity, a first cylindrical internal element which in the interior extends in the longitudinal direction of the reactor and which delimits the zone of limited backmixing from the backmixed zone, backmixing-preventing second internal elements in the form of random packings, structured packings or liquid-permeab
    Type: Application
    Filed: September 3, 2019
    Publication date: November 18, 2021
    Inventors: Oliver BEY, Peter ZEHNER, Andreas KELLER, Stephanie RENZ, Mathias SCHELWIES, Rocco PACIELLO, Martin HAUBNER, Guenter WEGNER, Gerd TEBBEN, Gunnar HEYDRICH, Georg SEEBER
  • Patent number: 11136611
    Abstract: The invention provides an improved method of isolating the 3-(E)-isomer of an unsaturated carboxylic acid from a mixture of corresponding (E/Z)isomers. More particularly, the present invention relates to an improved method for the biocatalytic preparation of (3E,7E)-homofarnesylic acid; as well as a novel biocatalytic method for the improved preparation of homofarnesol, in particular of (3E,7E)-homofarnesol and homofarnesol preparations having an increased content of (3E,7E)-homofarnesol. The present invention also relates to methods of preparing(?)-ambroxby applying (3E,7E)-homofarnesylic acid or (3E,7E)-homofarnesol as obtained according to the invention as starting material.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: October 5, 2021
    Assignee: BASF SE
    Inventors: Wolfgang Siegel, Melanie Weingarten, Michael Breuer, Mathias Schelwies
  • Publication number: 20210275987
    Abstract: A reactor for performing a reaction between two immiscible fluids of different density, comprising an interior formed by a cylindrical, vertically oriented elongate shell, a bottom and a cap, wherein the interior is divided by internals into a backmixed zone, a zone of limited backmixing preferably arranged below the backmixed zone and a plug-flow zone which are at least consecutively traversable by one of the fluids, wherein the backmixed zone comprises at least one inlet and the plug-flow zone comprises an outlet and the backmixed zone comprises at least one mixing apparatus selected from a stirrer, a jet nozzle and means for injecting the fluid of lower density, a first cylindrical internal element which in the interior extends in the longitudinal direction of the reactor, which delimits the zone of limited backmixing from the plug-flow zone and which comprises a first passage to the backmixed zone and a second passage to the plug-flow zone, a second internal element which delimits the backmixed zone from
    Type: Application
    Filed: September 3, 2019
    Publication date: September 9, 2021
    Inventors: Oliver BEY, Peter ZEHNER, Mathias SCHELWIES, Rocco PACIELLO, Martin HAUBNER, Guenter WEGNER, Gerd TEBBEN, Gunnar HEYDRICH, Georg SEEBER, Michael ACKER
  • Publication number: 20210009495
    Abstract: The present invention relates to a method for isomerizing a 3-(Z)-unsaturated carboxylic acid of the formula 1-Z or a salt thereof, wherein R2 is C1-C24-alkyl, C2-C24-alkenyl having 1, 2, 3 or more than 3 C—C double bonds, unsubstituted or substituted C5-C12-cycloalkyl, or unsubstituted or substituted aryl; R1 is hydrogen or has one of the definitions specified for R2; with the proviso that R2 has a higher priority than R1 in accordance with IUPAC; to give a 3-(E)-unsaturated carboxylic acid of the formula I-E or a salt thereof, wherein the isomerization of the compound of the formula 1-Z is effected in the presence of an anhydride of an organic acid and a base or in the presence of a ketene of formula CR11R12C(0), wherein R11 and R12 are as defined in the claims and in the specification and a base.
    Type: Application
    Filed: February 13, 2019
    Publication date: January 14, 2021
    Inventors: Mathias SCHELWIES, Wolfgang SIEGEL, Rocco PACIELLO, Andreas KELLER
  • Publication number: 20200398261
    Abstract: The present invention relates to the use of a transition metal catalyst TMC1, which comprises a transition metal M selected from metals of groups 7, 8, 9 and 10 of the periodic table of elements according to IUPAC and a tetradentate ligand of formula I wherein R1 are identical or different and are each an organic radical having from 1 to 40 carbon atoms, and R2 are identical or different and are each an organic radical having from 1 to 40 carbon atoms, as catalyst in processes for formation of compounds comprising at least one carboxylic acid ester functional group —O—C(?O)— starting from at least one primary alcohol and/or hydrogenation of compounds comprising at least one carboxylic acid ester functional group —O—C(?O)—.
    Type: Application
    Filed: January 10, 2019
    Publication date: December 24, 2020
    Applicant: BASF SE
    Inventors: Thomas SCHAUB, Aviel ANABY, Mathias SCHELWIES, Rocco PACIELLO, Jonas SCHWABEN, A. Stephen K HASHMI
  • Publication number: 20200123586
    Abstract: The invention provides an improved method of isolating the 3-(E)-isomer of an unsaturated carboxylic acid from a mixture of corresponding (E/Z)isomers. More particularly, the present invention relates to an improved method for the biocatalytic preparation of (3E,7E)-homofarnesylic acid; as well as a novel biocatalytic method for the improved preparation of homofarnesol, in particular of (3E,7E)-homofarnesol and homofarnesol preparations having an increased content of (3E,7E)-homofarnesol. The present invention also relates to methods of preparing(?)-ambroxby applying (3E,7E)-homofarnesylic acid or (3E,7E)-homofarnesol as obtained according to the invention as starting material.
    Type: Application
    Filed: February 23, 2018
    Publication date: April 23, 2020
    Inventors: Wolfgang SIEGEL, Melanie WEINGARTEN, Michael BREUER, Mathias SCHELWIES
  • Publication number: 20200055834
    Abstract: The present invention relates to a process for carbonylating allyl alcohols at low temperature, low pressure and/or low catalyst loading. In an alternative embodiment, an acylation product of the allyl alcohol is used for the carbonylation. The present invention likewise relates to the preparation of conversion products of these carbonylation products and specifically of (?)-ambrox.
    Type: Application
    Filed: February 13, 2018
    Publication date: February 20, 2020
    Inventors: Mathias SCHELWIES, Rocco PACIELLO, Ralf PELZER, Wolfgang SIEGEL
  • Patent number: 10301244
    Abstract: The present invention relates to a process for the preparation of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral ?,?-unsaturated carbonyl compound with hydrogen in the presence of at least one optically active transition metal catalyst that is soluble in the reaction mixture and which has rhodium as catalytically active transition metal and a chiral, bidentate bisphosphine ligand, wherein the reaction mixture during the hydrogenation of the prochiral ?,?-unsaturated carbonyl compound additionally comprises at least one compound of the general formula (I): in which R1, R2: are identical or different and are C6- to C10-aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino; Z is a group CHR3R4 or aryl which is unsubstituted or carries one or more, e.g.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: May 28, 2019
    Assignee: BASF SE
    Inventors: Mathias Schelwies, Rocco Paciello, Gunnar Heydrich, Günter Wegner, Gerd-Dieter Tebben, Martin Haubner, Andreas Keller, Oliver Bey, Stephanie Renz, Georg Seeber
  • Patent number: 10093606
    Abstract: The present invention relates to a process for preparing farnesyl acetone.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: October 9, 2018
    Assignee: BASF SE (REITSTÖTTER, KINZEBACH & PARTNER)
    Inventors: Mathias Schelwies, Rocco Paciello, Heinz Eckhardt, Martine Dehn
  • Publication number: 20180244598
    Abstract: The present invention relates to a process for the preparation of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral ?,?-unsaturated carbonyl compound with hydrogen in the presence of at least one optically active transition metal catalyst that is soluble in the reaction mixture and which has rhodium as catalytically active transition metal and a chiral, bidentate bisphosphine ligand, wherein the reaction mixture during the hydrogenation of the prochiral ?,?-unsaturated carbonyl compound additionally comprises at least one compound of the general formula (I): in which R1, R2: are identical or different and are C6- to C10-aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino; Z is a group CHR3R4 or aryl which is unsubstituted or carries one or more, e.g.
    Type: Application
    Filed: April 27, 2018
    Publication date: August 30, 2018
    Inventors: Mathias SCHELWIES, Rocco PACIELLO, Gunnar HEYDRICH, Günter WEGNER, Gerd-Dieter TEBBEN, Martin HAUBNER, Andreas KELLER, Oliver BEY, Stephanie RENZ, Georg SEEBER
  • Patent number: 9975837
    Abstract: The present invention relates to a process for the preparation of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral ?,?-unsaturated carbonyl compound with hydrogen in the presence of at least one optically active transition metal catalyst that is soluble in the reaction mixture and which has rhodium as catalytically active transition metal and a chiral, bidentate bisphosphine ligand, wherein the reaction mixture during the hydrogenation of the prochiral ?,?-unsaturated carbonyl compound additionally comprises at least one compound of the general formula (I): in which R1, R2: are identical or different and are C6- to C10-aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino; Z is a group CHR3R4 or aryl which is unsubstituted or carries one or more, e.g.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: May 22, 2018
    Assignee: BASF SE
    Inventors: Mathias Schelwies, Rocco Paciello, Gunnar Heydrich, Günter Wegner, Gerd-Dieter Tebben, Martin Haubner, Andreas Keller, Oliver Bey, Stephanie Renz, Georg Seeber
  • Publication number: 20180057437
    Abstract: The present invention relates to a process for the preparation of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral ?,?-unsaturated carbonyl compound with hydrogen in the presence of at least one optically active transition metal catalyst that is soluble in the reaction mixture and which has rhodium as catalytically active transition metal and a chiral, bidentate bisphosphine ligand, wherein the reaction mixture during the hydrogenation of the prochiral ?,?-unsaturated carbonyl compound additionally comprises at least one compound of the general formula (I): in which R1, R2: are identical or different and are C6- to C10-aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino; Z is a group CHR3R4 or aryl which is unsubstituted or carries one or more, e.g.
    Type: Application
    Filed: December 18, 2015
    Publication date: March 1, 2018
    Inventors: Mathias SCHELWIES, Rocco PACIELLO, Gunnar HEYDRICH, Günter WEGNER, Gerd TEBBEN, Martin HAUBNER, Andreas KELLER, Oliver BEY, Stephanie RENZ, Georg SEEBER
  • Publication number: 20170044084
    Abstract: The present invention relates to a process for preparing farnesyl acetone.
    Type: Application
    Filed: April 29, 2015
    Publication date: February 16, 2017
    Inventors: Mathias SCHELWIES, Rocco PACIELLO, Heinz ECKHARDT, Martine DEHN
  • Publication number: 20160347908
    Abstract: The present invention relates to a process for producing nylon-6,6 by a) providing a muconic acid starting material selected from muconic acid, esters of muconic acid, lactones of muconic acid and mixtures thereof, b) subjecting the muconic acid starting material provided in step a) at least to some extent to a reaction with hydrogen in the presence of at least one hydrogenation catalyst Hb) to give adipic acid, c1) subjecting the muconic acid starting material provided in step a) to some extent to a reaction with hydrogen in the presence of at least one hydrogenation catalyst Hc1) to give 1,6-hexanediol, or c2) subjecting the adipic acid obtained in step b) to some extent to a reaction with hydrogen in the presence of at least one hydrogenation catalyst Hc2) to give 1,6-hexanediol, d) subjecting the 1,6-hexanediol obtained in step c1) or c2) to amination in the presence of an amination catalyst to obtain hexamethylenediamine, e) subjecting the hexamethylenediamine obtained in step d) and at least a portion o
    Type: Application
    Filed: December 12, 2014
    Publication date: December 1, 2016
    Inventors: Christoph MÜLLER, Matin BOCK, Marion DA SILVA, Rolf-Hartmuth FISCHER, Benoit BLANK, Alois KINDLER, Johann-Peter MELDER, Bernhard OTTO, Mathias SCHELWIES, Andreas HENNINGER
  • Patent number: RE46374
    Abstract: Process for preparing primary amines which have at least one functional group of the formula (—CH2—NH2) and at least one further primary amino group by alcohol amination of starting materials having at least one functional group of the formula (—CH2—OH) and at least one further functional group (—X), where (—X) is selected from among hydroxyl groups and primary amino groups, by means of ammonia with elimination of water, wherein the reaction is carried out homogeneously catalyzed in the presence of at least one complex catalyst comprising at least one element selected from groups 8, 9 and 10 of the Periodic Table and also at least one donor ligand.
    Type: Grant
    Filed: February 23, 2016
    Date of Patent: April 25, 2017
    Assignee: BASF SE
    Inventors: Thomas Schaub, Boris Buschhaus, Marion Kristina Da Silva, Mathias Schelwies, Rocco Paciello, Johann-Peter Melder, Martin Merger
  • Patent number: RE49036
    Abstract: The present invention relates to a process for the preparation of an optically active carbonyl compound by asymmetric hydrogenation of a prochiral ?,?-unsaturated carbonyl compound with hydrogen in the presence of at least one optically active transition metal catalyst that is soluble in the reaction mixture and which has rhodium as catalytically active transition metal and a chiral, bidentate bisphosphine ligand, wherein the reaction mixture during the hydrogenation of the prochiral ?,?-unsaturated carbonyl compound additionally comprises at least one compound of the general formula (I): in which R1, R2: are identical or different and are C6- to C10-aryl which is unsubstituted or carries one or more, e.g. 1, 2, 3, 4 or 5, substituents which are selected from C1- to C6-alkyl, C3- to C6-cycloalkyl, C6- to C10-aryl, C1- to C6-alkoxy and amino; Z is a group CHR3R4 or aryl which is unsubstituted or carries one or more, e.g.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: April 19, 2022
    Assignee: BASF SE
    Inventors: Mathias Schelwies, Rocco Paciello, Gunnar Heydrich, Günter Wegner, Gerd-Dieter Tebben, Martin Haubner, Andreas Keller, Oliver Bey, Stephanie Renz, Georg Seeber