Abstract: The present invention is related to agents capable of binding to and inhibiting or antagonizing the action of IL-11 and/or or IL-11RA for the treatment and/or prevention of abnormal uterine bleeding, which comprises heavy menstrual bleeding, prolonged bleeding, altered bleeding pattern, dysmenorrhea, as well as of the underlying diseases leiomyoma and endometriosis and the use of the agent to inhibit menstruation. Furthermore, the invention provides novel IL-11 antibodies.

Abstract: The present invention relates to methods, kits and systems for the prognosis of the disease outcome of breast cancer, said method comprising: (a) determining in a tumor sample from said patient the RNA expression levels of at least 2 of the following 9 genes: UBE2C, BIRC5, RACGAP1, DHCR7, STC2, AZGP1, RBBP8, IL6ST, and MGP (b) mathematically combining expression level values for the genes of the said set which values were determined in the tumor sample to yield a combined score, wherein said combined score is indicative of a prognosis of said patient; and kits and systems for performing said method.

Abstract: The present invention relates to a membrane electrode unit comprising a polymer membrane doped with a mineral acid as well as two electrodes, characterized in that the polymer membrane comprises at least one polymer with at least one nitrogen atom and at least one electrode comprises a catalyst which is formed from at least one precious metal and at least one metal less precious according to the electrochemical series.

Abstract: The present invention relates to a membrane electrode unit comprising a polymer membrane doped with a mineral acid as well as two electrodes, characterized in that the polymer membrane comprises at least one polymer with at least one nitrogen atom and at least one electrode comprises a catalyst which is formed from at least one precious metal and at least one metal less precious according to the electrochemical series.

Abstract: An inductive device comprises a plate-shaped ferrite core and a hybrid double-D solenoid coil which is arranged over the plate-shaped ferrite core and has a plurality of turns. The plurality of turns is grouped into at least two groups, each having at least two immediately consecutive turns which in a group have monotonically increasing or decreasing turn diameters, wherein the last turn of a group has a turn diameter that is larger than that of the first turn of the following group if the turn diameter of the turn immediately preceding the last turn within the group is smaller than the turn diameter of the last turn, or has a turn diameter that is smaller than that of the first turn of the following group if the turn diameter of the turn immediately preceding the last turn is larger than the turn diameter of the last turn.

Abstract: A compostable material and methods of forming the same are described. The compostable material includes about 90% to about 99% by weight of a compostable polymeric material and a nucleating agent. The compostable material has a degree of crystallinity of about 5% to about 45%.

Abstract: A load control system may control an electrical load in a space of a building occupied by an occupant. The load control system may include a controller configured to determine the location of the occupant, and a load control device configured to automatically control the electrical load in response to the location of the occupant. The load control system may also include a mobile device adapted to be located on or immediately adjacent the occupant and configured to transmit and receive wireless signals. The load control device may be configured to automatically control the electrical load when the mobile device is located in the space. The load control system may further comprise an occupancy sensor and the load control device may automatically control the electrical load when the occupancy sensor indicates that the space is occupied and the mobile device is located in the space.

Abstract: An inductive device comprises a plate-shaped ferrite core and a hybrid double-D solenoid coil which is arranged over the plate-shaped ferrite core and has a plurality of turns. The plurality of turns is grouped into at least two groups, each having at least two immediately consecutive turns which in a group have monotonically increasing or decreasing turn diameters, wherein the last turn of a group has a turn diameter that is larger than that of the first turn of the following group if the turn diameter of the turn immediately preceding the last turn within the group is smaller than the turn diameter of the last turn, or has a turn diameter that is smaller than that of the first turn of the following group if the turn diameter of the turn immediately preceding the last turn is larger than the turn diameter of the last turn.

Abstract: An exhaust-gas turbocharger (1) having a compressor (2) which has a compressor housing (3); having a turbine (4) which has a turbine housing (5); and having a charge-pressure regulating device (6). The charge-pressure regulating device (6) has at least two flap arrangements (7, 8) and two bypass duct openings (9, 10) assigned to the flap arrangements (7, 8).

Abstract: A load control system may control an electrical load in a space of a building occupied by an occupant. The load control system may include a controller configured to determine the location of the occupant, and a load control device configured to automatically control the electrical load in response to the location of the occupant. The load control system may also include a mobile device adapted to be located on or immediately adjacent the occupant and configured to transmit and receive wireless signals. The load control device may be configured to automatically control the electrical load when the mobile device is located in the space. The load control system may further comprise an occupancy sensor and the load control device may automatically control the electrical load when the occupancy sensor indicates that the space is occupied and the mobile device is located in the space.

Abstract: An exhaust-gas turbocharger (1) having a compressor (2) which has a compressor housing (3); having a turbine (4) which has a turbine housing (5); and having a charge-pressure regulating device (6). The charge-pressure regulating device (6) has at least two flap arrangements (7, 8) and two bypass duct openings (9, 10) assigned to the flap arrangements (7, 8).

Abstract: A method for manufacturing a micromechanical component includes the following sequential steps: a first material layer including a first joining partner being applied to a first wafer; a second material layer including a second joining partner being applied to a second wafer; a micromechanical structure being created in the first wafer by gas phase etching with the aid of a gaseous etching medium which is applied to the first joining partner; the first and second wafers being joined in such a way that they are in contact at least in some areas; and the first and second joining partners being heated to be integrally joined to form a connecting layer, a eutectic joining material being formed in the connecting layer from the first joining partner and the second joining partner.

Abstract: The present invention relates to a method for the conditioning of membrane electrode assemblies for fuel cells in which the output of the membrane electrode assemblies used can be increased and therefore the efficiency of the resulting polymer electrolyte membrane fuel cells can be improved.

Abstract: The present invention relates to a method for the conditioning of membrane electrode assemblies for fuel cells in which the output of the membrane electrode assemblies used can be increased and therefore the efficiency of the resulting polymer electrolyte membrane fuel cells can be improved.

Abstract: A loudspeaker comprises a voice coil and a diaphragm attached to the voice coil. The diaphragm has a generally rectangular outer shape, and comprises an outer rim (A1) having an outer edge at which the diaphragm is fixed in position and an inner section (A0) within the outer rim. The inner section (A0) comprises: an outermost area (A00) which is coupled to the voice coil and having the same generally rectangular outer shape; and an inner area (A01) comprising a periodic rib structure (A01p), with the ribs running parallel to the shorter side of the rectangular outer shape, and two lateral transition areas (A01c) between the edges of the periodic rib structure (A01p) and the shorter side edges of outermost area (A00).