Patents by Inventor Mathieu Jean-Francois Desclaux

Mathieu Jean-Francois Desclaux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lentiviral vectors allowing RNAi mediated inhibition of GFAP and vimentin expression
    Publication number: 20100098664
    Abstract: The present invention relates to method for preventing, treating or alleviating a central nervous system (CNS) disorder using a non replicative lentivirus comprising a lentiviral genome comprising a nucleic acid sequence producing at least one functional miRNA, at least one functional shRNA and/or at least one functional siRNA, preferably derived from said shRNA, said miRNA, shRNA or siRNA being designed to silence the expression of a gene that encodes a protein of the astrocyte cytoskeleton. The present invention further relates to compositions and kits comprising such a lentivirus as well as to uses thereof.
    Type: Application
    Filed: November 28, 2007
    Publication date: April 22, 2010
    Inventors: Mathieu Jean-Francois Desclaux, Jacques Mallet, Alain Privat, Minerva Gimenez y Ribotta