Abstract: An adhesive composition comprises a silylated polymer (A) comprising a group of formula (I) and a catalyst (B) of formula (V). In formula (I): —Si(R4)p(OR5)3-p, each R4 independently represents a linear or branched alkyl radical comprising from 1 to 4 carbon atoms; each R5 independently represents a linear or branched alkyl radical comprising from 1 to 10 carbon atoms and optionally comprising one or more heteroatoms chosen from oxygen and nitrogen, or two OR5 groups are involved in the same ring comprising from 2 to 8 carbon atoms; p is an integer equal to 0, 1 or 2. In formula (V): B(OH)R?R?, R? represents a substituted or unsubstituted aryl group; and R? is chosen from an OH group and a substituted or unsubstituted aryl group.

Abstract: The present invention relates to a process for preparing a mixture M1 of enol phosphate isomers devoid of (E,E) isomer and comprising at least 98% of (E,Z) isomer, at least 0.1% of (Z,Z) isomer and at least 0.1% of (Z,E) isomer, comprising bringing a mixture of isomers of said enol phosphate comprising a detectable amount of (E,E) isomer into contact with a hydrolysable dienophile in an organic solvent, followed by base hydrolysis of the medium obtained and elimination of the adduct formed, in order to obtain the mixture M1 devoid of (E,E) isomer.

Abstract: The present invention relates to a two-component composition comprising a first part (A) comprising a borane BH3-amine complex and an alkene compound, and a second part (B) comprising at least one radically polymerizable compound comprising at least one ethylenic bond, and to an adhesive composition obtained therefrom, and also to uses thereof. The invention also relates to articles made with this composition.

Abstract: The present invention relates to a process for polymerizing at least one radically polymerizable compound comprising at least one ethylenic bond, in the presence of a borane BH3-amine complex and an alkene.

Abstract: The present invention relates to a process for preparing a mixture M1 of enol phosphate isomers devoid of (E,E) isomer and comprising at least 98% of (E,Z) isomer, at least 0.1% of (Z,Z) isomer and at least 0.1% of (Z,E) isomer, comprising bringing a mixture of isomers of said enol phosphate comprising a detectable amount of (E,E) isomer into contact with a hydrolysable dienophile in an organic solvent, followed by base hydrolysis of the medium obtained and elimination of the adduct formed, in order to obtain the mixture M1 devoid of (E,E) isomer.

Abstract: Disclosed is a method for preparing alkenyl aminoboranes and their derivatives, and uses thereof. The method for preparing alkenyl aminoboranes includes contacting, preferably in a single synthesis step, a terminal alkyne, an aminoborane and a catalyst chosen from Schwartz's reagent (Cp2ZrHCl), dicyclohexylborane (HBCy), diisopinocamphenylborane (HBipc2) and 9-Borabicyclo(3.3.1)nonane (9-BBN).

Abstract: The invention relates to Orai1-dependent selective capacitative calcium entry inhibitors as well as to the therapeutic use thereof.

Abstract: The invention relates to a process for polymerizing at least one radically polymerizable compound having at least one ethylenic bond in the presence of a borane complex BH3 with an amine as a radical initiator, said process comprising the steps of: providing a borane complex BH3 with an amine; and bringing the complex into contact with a composition comprising at least one radically polymerizable compound having at least one ethylenic bond; wherein the polymerization is performed in the absence of an oxidizing agent and/or an additional radical initiator other than the borane complex BH3 with an amine. The invention also relates to a composition comprising at least one radically polymerizable compound having at least one ethylenic bond and a borane complex BH3 with an amine, wherein the composition is free of an oxidizing agent and/or an additional radical initiator other than the borane complex BH3 with an amine, as well as the use of said composition as an adhesive for bonding two substrates together.

Abstract: The invention relates to a two-component composition comprising: a part A comprising a complex of borane BH3 with an amine; a part B comprising a decomplexing agent for decomplexing the borane and the amine; and at least one radically polymerizable compound comprising at least one ethylenic bond, this compound being present in at least one of parts A and B; and also to the use of this composition as an adhesive for binding two substrates together.

Abstract: Disclosed are novel alkynyl aminoboranes, wherein the method for preparing same includes bringing into contact in a single synthesis step a terminal alkyne, an aminoborane and an organomagnesium, in particular a Grignard reagent.

Abstract: The present invention relates to a process for preparing a mixture M1 of enol phosphate isomers devoid of (E,E) isomer and comprising at least 98% of (E,Z) isomer, at least 0.1% of (Z,Z) isomer and at least 0.1% of (Z,E) isomer, comprising bringing a mixture of isomers of said enol phosphate comprising a detectable amount of (E,E) isomer into contact with a hydrolysable dienophile in an organic solvent, followed by base hydrolysis of the medium obtained and elimination of the adduct formed, in order to obtain the mixture M1 devoid of (E,E) isomer.

Abstract: A process for preparing an aromatic compound or compounds where at least one mandelic group —CHOH—COOH is described, comprising a reaction for condensation of at least one aromatic compound with glyoxylic acid or derivatives thereof, wherein said condensation reaction is carried out substantially in the absence of any acid or any base added to the reaction medium. The condensation reaction is followed by an oxidation reaction in order to obtain aromatic aldehyde.

Abstract: A process for preparing an aromatic compound or compounds where at least one mandelic group —CHOH—COOH is described, comprising a reaction for condensation of at least one aromatic compound with glyoxylic acid or derivatives thereof, wherein said condensation reaction is carried out substantially in the absence of any acid or any base added to the reaction medium. The condensation reaction is followed by an oxidation reaction in order to obtain aromatic aldehyde.

Abstract: Process for the synthesis of the compound of formula (I): Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

Abstract: Task-specific onium salts, process for preparing them and use thereof for detecting and assaying metals, in particular heavy metals, in an aqueous medium.