Patents by Inventor Mathieu Sassatelli

Mathieu Sassatelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymer derived from linear polyethylenimine for gene transfer
    Patent number: 8658150
    Abstract: The invention relates to a static copolymer of linear polyethylenimine that comprises two monomer units of the following formulas I and II, in which R1 is a hydrogen atom or a C1-C6 alkyl radical, R2 is a hydrogen atom, a C1-C6 alkyl, aryl or aralkyl group, wherein the alkyl group is a C1-C6 one, n is a number between 1 and 99% of the total monomers, m is a number between 1 and 99% of the total monomers, and advantageously m+n=100%. The invention also relates to complexes of this copolymer with a nucleic acid, and to the use thereof in in vivo, in vitro or ex vivo gene transfection.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: February 25, 2014
    Assignees: Centre National de la Recherche Scientifique, Universite d'Orleans, Universite d'Evry val d'Essonne
    Inventors: Hervé Cheradame, Mathieu Sassatelli, Philippe Guegan, Patrick Midoux, Chantal Pichon
  • POLYMER DERIVED FROM LINEAR POLYETHYLENIMINE FOR GENE TRANSFER
    Publication number: 20110091407
    Abstract: The invention relates to a static copolymer of linear polyethylenimine that comprises two monomer units of the following formulas I and II, in which R1 is a hydrogen atom or a C1-C6 alkyl radical, R2 is a hydrogen atom, a C1-C6 alkyl, aryl or aralkyl group, wherein the alkyl group is a C1-C6 one, n is a number between 1 and 99% of the total monomers, m is a number between 1 and 99% of the total monomers, and advantageously m+n=100%. The invention also relates to complexes of this copolymer with a nucleic acid, and to the use thereof in in vivo, in vitro or ex vivo gene transfection.
    Type: Application
    Filed: March 4, 2009
    Publication date: April 21, 2011
    Inventors: Hervé Cheradame, Mathieu Sassatelli, Philippe Guegan, Patrick Midoux, Chantal Pichon