Abstract: An oil-in-water emulsion for intravitreal administration, especially injection, including an active ingredient, an oil, a mixture of two non-ionic surfactants and water, the emulsion having a droplet size ranging from about 100 to about 200 nm. The emulsion avoids troubles of vision after administration into the vitreous body. The emulsion provides good therapeutic activity of the active ingredient for treating eye diseases or conditions, such as an eye disease or condition of the posterior segment of the eye.

Abstract: A pharmaceutical liquid suspension comprising: temozolomide or a salt thereof; at least one agent controlling the solid state of temozolomide in suspension; a pharmaceutically acceptable liquid vehicle; and optionally at least one acid in a quantity so that the pH of the composition is below 5; or a powder blend for reconstituting said suspension, is provided.

Abstract: Methods of and systems provide service redundancy between a master server and a slave server. The master server provides access to a pool of resources to a client. In response to detecting a fault on the master server, the master server is marked as disabled and services held on the master server are switched to the slave server and to a secondary pool of resources. The master service may be restarted if down. Then, provided that the master server is up, one or more tests are performed on the master server. The master server is marked as enabled if the tests are successful. The services may be switched back to the master server when the server is enabled. Services may further be rolled back to the slave server in case of an additional fault occurrence. The technique may also be used for updating a configuration in a service infrastructure.

Abstract: The present invention concerns a pharmaceutical composition, advantageously a liquid suspension, comprising: a. temozolomide or a salt thereof; b. at least one agent controlling the solid state of temozolomide in suspension; c. a pharmaceutically acceptable liquid vehicle, advantageously water; d. optionally at least one acid in a quantity so that the pH of the composition is below 5; or a powder blend for reconstituting said suspension.

Abstract: Methods of and systems provide service redundancy between a master server and a slave server. The master server provides access to a pool of resources to a client. In response to detecting a fault on the master server, the master server is marked as disabled and services held on the master server are switched to the slave server and to a secondary pool of resources. The master service may be restarted if down. Then, provided that the master server is up, one or more tests are performed on the master server. The master server is marked as enabled if the tests are successful. The services may be switched back to the master server when the server is enabled. Services may further be rolled back to the slave server in case of an additional fault occurrence. The technique may also be used for updating a configuration in a service infrastructure.

Abstract: Disclosed is a composition for use for topical administration onto the upper and/or lower eyelid of a subject. The composition includes a polyaphron, and the polyaphron includes: at least one hydrophilic phase; at least one hydrophobic phase; and at least one surfactant selected from ionic surfactants and/or non-ionic surfactants.