Abstract: A multi-dose dispenser comprising an inner housing (16) and an outer housing (12), the inner housing (16) being movable within the outer housing (12) for a defined distance, a plunger rod (20) comprising a shaft (66) mounted within the inner housing (16), the shaft (66) having a plurality of spaced apart teeth (68) formed on the shaft (66), an actuator (22) located at one end of the shaft (66), the inner housing (16) having at least one pawl (70) arranged to engage with the teeth (68), a syringe (74) mounted interiorly of the inner housing (16), the syringe (74) being arranged such that the shaft (66) engages with a plunger within the syringe (74), and a spring member (18), the spring member (18) being biased between the inner housing (16) and the outer housing (12).

Abstract: A reconstitution device comprising a cartridge (212) containing a first substance, the cartridge having a plunger (238) at one end and a piercable septum (222) at a second end, a vial (218) containing a second substance, the vial having a piercable septum (224), a housing (210), a cartridge needle hub (226), the cartridge needle hub (226) having a needle (228) protruding therefrom, a vial needle hub (229), the vial needle hub having a needle (222) protruding therefrom, the vial needle hub (229) and the cartridge needle hub (226) being releasably securable together, cartridge latches (240) holding the cartridge needle hub (226) within the housing, vial needle hub latches (231) extending to engage the housing, and a plunger rod (232), the plunger rod having an inner portion (234) engageable with the plunger (238) of the cartridge, the plunger rod (232) having an outer portion (236) which is adapted to engage the vial needle hub latches (240) to release the vial needle hub (229) from engagement with the cartridg

Abstract: A method of sterilizing a cartridge (10), the cartridge (10) having a side wall (12) and a medicant therein; placing the cartridge (10) within an outer sleeve (18); sealing the sleeve in the side wall (12) of the cartridge (10) with a wiper seal (34) to form a hermetic microbial barrier; providing a breathable microbial membrane (38) over one end of the sleeve (18); subjecting the cartridge (10) and the outer sleeve (18) to a gas sterilization; and removing any sterilizing gas remaining after sterilization.

Abstract: A multi-dose injector comprising an inner housing (16) and an outer housing (12), the inner housing (16) being movable within the outer housing for a defined distance, a plunger rod (20) comprising a shaft (66) mounted within the inner housing (16) the shaft (66) having a plurality of spaced apart teeth (68) formed thereon, an actuator (22) located at one end of the shaft (66), the inner housing (16) having at least one pawl (70) arranged to engage with the teeth (68), a syringe (74) mounted interiorly of the inner housing (16), the syringe being arranged such that the shaft engages with a plunger within the syringe, and a spring member (18), the spring member (18) being biased between the inner housing (16) and the outer housing (12).

Abstract: A auto-injector device having a housing (212, 214), a cartridge for containing a medicament, a first needle tip (230) arranged to penetrate said cartridge, a second needle tip (230) for injecting said medicament into a target, said first and second needle tips being in fluid communication, a plunger rod (242) to move said cartridge so as to be pierced by said first needle tip, said plunger rod (242) having a recess (270) in an end thereof, the improvement comprising a battery (258), a printed circuit board (250) electrically communicating with said battery, an electrically conductive element (274) having a first end in electric communication with said battery (258) and printed circuit board (250), a second end within said recess (270) in said plunger rod (242), said second end being electrically insulated, a coil spring (246) surrounding said electrically conductive element and being spaced therefrom, the arrangement being such that when said plunger rod (242) is activated, said second end of said electricall

Abstract: A transfer member (128) comprising a housing (24) having a top, a side wall (26), an open bottom, the open bottom permitting insertion of a vial (12) within the housing, a piercing member (34) mounted within the housing (24), the piercing member (34) having a piercing tip (36) located at a bottom end thereof, the piercing member having an interior passageway formed therein, a connector (30) located on an exterior side of the top, a moveable member (40) mounted within the housing (24), the moveable member (40) being moveable from a first position wherein the moveable member (40) prevents access to the piercing tip (36) to a second position permitting access to the piercing tip when the vial is inserted in the housing, a transfer member (128), the transfer member (128) having first and second transfer member ends (131, 133) wherein the moveable member (40) and the housing (24) cause the moveable member (40) to rotate when the moveable member (40) moves upwardly upon insertion of the vial (12), the moveable memb

Abstract: A auto-injector device having a housing (212, 214), a cartridge for containing a medicament, a first needle tip (230) arranged to penetrate said cartridge, a second needle tip (230) for injecting said medicament into a target, said first and second needle tips being in fluid communication, a plunger rod (242) to move said cartridge so as to be pierced by said first needle tip, said plunger rod (242) having a recess (270) in an end thereof, the improvement comprising a battery (258), a printed circuit board (250) electrically communicating with said battery, an electrically conductive element (274) having a first end in electric communication with said battery (258) and printed circuit board (250), a second end within said recess (270) in said plunger rod (242), said second end being electrically insulated, a coil spring (246) surrounding said electrically conductive element and being spaced therefrom, the arrangement being such that when said plunger rod (242) is activated, said second end of said electricall

Abstract: A transfer member (128) comprising a housing (24) having a top, a side wall (26), an open bottom, the open bottom permitting insertion of a vial (12) within the housing, a piercing member (34) mounted within the housing (24), the piercing member (34) having a piercing tip (36) located at a bottom end thereof, the piercing member having an interior passageway formed therein, a connector (30) located on an exterior side of the top, a moveable member (40) mounted within the housing (24), the moveable member (40) being moveable from a first position wherein the moveable member (40) prevents access to the piercing tip (36) to a second position permitting access to the piercing tip when the vial is inserted in the housing, a transfer member (128), the transfer member (128) having first and second transfer member ends (131, 133) wherein the moveable member (40) and the housing (24) cause the moveable member (40) to rotate when the moveable member (40) moves upwardly upon insertion of the vial (12), the moveable memb

Abstract: A reconstitution arrangement for transferring the contents of a first container (136) with the contents of a second container (110) and subsequently retransferring the mixture to the first container (136), the arrangement including a transfer device (114) having a fluid passageway extending between first and second ends (111, 113), a cartridge holder (138) secured to second end (113) of the transfer device, the cartridge holder (138) having a needle (144, 145) with first and second piercing tips (117, 119), the first piercing tip (117) extending into the fluid passageway of the transfer device, a first container receiving portion (115) having the second piercing tip (119) extending therein and being arranged to receive the first container (136), a housing (118) secured to the cartridge holder with a plunger rod (122) within the housing, and a cover (130) extending over the transfer device (114), cartridge holder (138) and housing (118), the cover and transfer device having an interlocking arrangement to preve

Abstract: A transfer arrangement comprising a syringe (110) having a side wall defining a cavity (116) which is sealed by plunger (114), a needle (119) being connected to a second syringe end (113), an adaptor (124) having a first adaptor end (121) connecting to the second syringe end (113), the adaptor (124) extending about the needle (119), second adaptor end (123) having a luer connector (126), and a transfer member (128) having first and second transfer member ends (131, 133) with the first transfer member end (131) being connected to the second adaptor end (123) while the second transfer member end (133) receives the neck of a vial (130).

Abstract: A reconstitution arrangement for transferring the contents of a first container (136) with the contents of a second container (110) and subsequently retransferring the mixture to the first container (136), the arrangement including a transfer device (114) having a fluid passageway extending between first and second ends (111, 113), a cartridge holder (138) secured to second end (113) of the transfer device, the cartridge holder (138) having a needle (144, 145) with first and second piercing tips (117, 119), the first piercing tip (117) extending into the fluid passageway of the transfer device, a first container receiving portion (115) having the second piercing tip (119) extending therein and being arranged to receive the first container (136), a housing (118) secured to the cartridge holder with a plunger rod (122) within the housing, and a cover (130) extending over the transfer device (114), cartridge holder (138) and housing (118), the cover and transfer device having an interlocking arrangement to preve

Abstract: A transfer arrangement comprising a syringe (110) having a side wall defining a cavity (116) which is sealed by plunger (114), a needle (119) being connected to a second syringe end (113), an adaptor (124) having a first adaptor end (121) connecting to the second syringe end (113), the adaptor (124) extending about the needle (119), second adaptor end (123) having a luer connector (126), and a transfer member (128) having first and second transfer member ends (131, 133) with the first transfer member end (131) being connected to the second adaptor end (123) while the second transfer member end (133) receives the neck of a vial (130).

Abstract: A reconstitution device (10) for mixing a first component (70) with a second component (72) wherein there are provided first and seconds housings (12, 14) which are engageable together, a conduit (28) having an internal passageway (30) having a dispensing end and an inlet end, first, second and third plungers (52, 54) mounted in said internal passageway (30), first and second compartments (70, 72) being defined by the plungers, a shearing channel (32) formed in a side wall of conduit (28) to permit mixing of contents located in the first and second compartments (74, 76), a plunger rod (58) to cause initial mixing of the first and second components (70, 72), and a spring member (48) biasing against the moveable member (42).

Abstract: A reconstitution device (10) for mixing a first component (70) with a second component (72) wherein there are provided first and seconds housings (12, 14) which are engageable together, a conduit (28) having an internal passageway (30) having a dispensing end and an inlet end, first, second and third plungers (52, 54) mounted in said internal passageway (30), first and second compartments (70, 72) being defined by the plungers, a shearing channel (32) formed in a side wall of conduit (28) to permit mixing of contents located in the first and second compartments (74, 76), a plunger rod (58) to cause initial mixing of the first and second components (70, 72), and a spring member (48) biasing against the moveable member (42).