Patents by Inventor Mathilda Sjöberg

Mathilda Sjöberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigen and method for production thereof
    Patent number: 10159729
    Abstract: The invention refers to a method for producing an antigen comprising at least one hydrophobic or partially hydrophobic antigen molecule from a virus, a bacterium, fungus, protozoan, parasite, a human neoplastic cell or an animal neoplastic, tumor or 5 cancer cell, the method comprising the steps of providing a virus, or cell comprising an antigen molecule, purifying the cell comprising the antigen molecule, solubilizing the antigen molecule in a solubilizing agent that preserves an intact antigen molecule upon solubilization and reconstituting the antigen molecule in a lipid-binding polypeptide that provides a lipid membrane mimicking environment and a reconstituted antigen particle 10 obtained by this method.
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: December 25, 2018
    Assignee: Sallpro Biotech AB
    Inventors: Robin Löving, Jens Frauenfeld, Gunilla Karlsson Hedestam, Henrik Garoff, Mathilda Sjöberg
  • ANTIGEN AND METHOD FOR PRODUCTION THEREOF
    Publication number: 20160220664
    Abstract: The invention refers to a method for producing an antigen comprising at least one hydrophobic or partially hydrophobic antigen molecule from a virus, a bacterium, fungus, protozoan, parasite, a human neoplastic cell or an animal neoplastic, tumour or 5 cancer cell, the method comprising the steps of providing a virus, or cell comprising an antigen molecule, purifying the cell comprising the antigen molecule, solubilizing the antigen molecule in a solubilizing agent that preserves an intact antigen molecule upon solubilisation and reconstituting the antigen molecule in a lipid-binding polypeptide that provides a lipid membrane mimicking environment and a reconstituted antigen particle 10 obtained by this method.
    Type: Application
    Filed: September 12, 2014
    Publication date: August 4, 2016
    Inventors: Robin Löving, Jens Frauenfeld, Gunilla Karlsson Hedestam, Henrik Garoff, Mathilda Sjöberg
  • Alphavirus expression vector
    Patent number: 6692750
    Abstract: The present invention is directed to alphavirus expression vectors comprising at least part of an alphavirus genome and heterologous RNA inserted downstream of an alphavirus base sequence having translation enhancing activity. Such vectors can be used to achieve enhanced levels of expression of DNA or cDNA coding for a desired product and being complementary to said heterologous RNA after introduction of said vector in eukaryotic cells in cell culture or in a living body. The expression product may have therapeutic or prophylactic activity.
    Type: Grant
    Filed: September 7, 2000
    Date of Patent: February 17, 2004
    Assignee: Bioption AB
    Inventors: Mathilda Sjöberg, Maarit Suomalainen, Henrik Garoff
  • Alphavirus expression vector
    Patent number: 6224879
    Abstract: The present invention is directed to alphavirus expression vectors comprising at least part of an alphavirus genome and heterologous RNA inserted downstream of an alphavirus base sequence having translation enhancing activity. Such vectors can be used to achieve enhanced levels of expression of DNA or cDNA coding for a desired product and being complementary to said heterologous RNA after introduction of said vector in eukaryotic cells in cell culture or in a living body. The expression product may have therapeutical or prophylactic activity.
    Type: Grant
    Filed: November 18, 1996
    Date of Patent: May 1, 2001
    Assignee: Bioption AB
    Inventors: Mathilda Sjöberg, Maarit Suomalainen, Henrik Garoff