Patents by Inventor Matias Melander
Matias Melander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240100258Abstract: A drug delivery device may include a housing defining a longitudinal axis and having an opening and a drug storage container including a delivery member having an insertion end configured to extend at least partially through the opening during a delivery state. The device may also include plunger moveable toward the distal end of the drug storage container to expel a drug from the drug storage container through the delivery member, the plunger including a body portion having an inner wall defining an axial chamber and an outer wall cooperating with the inner wall to define a body thickness. The device may further include a plunger biasing member disposed at least partially within the axial chamber, the plunger biasing member configured to urge the plunger toward the distal end of the drug storage container.Type: ApplicationFiled: December 8, 2023Publication date: March 28, 2024Applicant: AMGEN INC.Inventors: Emil FINKELSTEIN, Soren Forbech SKALL, Lars EILERTSEN, Matias MELANDER, Jan JENSEN
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Patent number: 11904143Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.Type: GrantFiled: June 4, 2018Date of Patent: February 20, 2024Assignee: AMGEN INC.Inventors: Adam B. McCullough, Ronald Forster, Joseph Michael Iglesias, Matias Melander, Rasmus Øhlenschlaeger, Christian Plambech, Lars Stenholt, Bjarke Lykke Ludvig Svendsen
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Patent number: 11878149Abstract: A drug delivery device may include a housing defining a longitudinal axis and having an opening and a drug storage container including a delivery member having an insertion end configured to extend at least partially through the opening during a delivery state. The device may also include plunger moveable toward the distal end of the drug storage container to expel a drug from the drug storage container through the delivery member, the plunger including a body portion having an inner wall defining an axial chamber and an outer wall cooperating with the inner wall to define a body thickness. The device may further include a plunger biasing member disposed at least partially within the axial chamber, the plunger biasing member configured to urge the plunger toward the distal end of the drug storage container.Type: GrantFiled: September 29, 2020Date of Patent: January 23, 2024Assignee: AMGEN INC.Inventors: Emil Finkelstein, Soren Forbech Skall, Lars Eilertsen, Matias Melander, Jan Jensen
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Publication number: 20230138654Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.Type: ApplicationFiled: June 4, 2018Publication date: May 4, 2023Inventors: Adam B. McCullough, Ronald Forster, Joseph Michael Iglesias, Matias Melander, Rasmus Øhelschlaeger, Christian Plambech, Lars Stenholt, Bjarke Lykke Ludvig Svendsen
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Publication number: 20210346594Abstract: The invention relates to an injection device for injecting a liquid drug. The injection device comprises a housing assembly supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected and a reusable needle cannula connected to the cartridge. A needle shield assembly provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections is further provided.Type: ApplicationFiled: July 22, 2021Publication date: November 11, 2021Inventors: Mie Haraldsted, Morten Revsgaard Frederiksen, Matias Melander, Christian Hoejris Nielsen, Graham Hinde, Bas Kamp, Roshan Hakkim
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Publication number: 20210346596Abstract: An approach for assembling a platform drug delivery device includes providing a set of base components and identifying, based on at least one desired characteristic of the platform drug delivery device, a rear sub-assembly for the drug delivery device from a group of rear sub-assemblies. The identified rear sub-assembly is selected, and a front sub-assembly is identified based on the at least one desired characteristic from a group of front sub-assemblies. The identified front-assembly is selected, and the drug delivery device is assembled using the set of base components, the rear sub-assembly, and the front sub-assembly.Type: ApplicationFiled: October 15, 2019Publication date: November 11, 2021Inventors: Jakob Halkjaer Pedersen, Matias Melander, Christian Plambech, Adam B. McCullough, Rasmus Ohlenschlager
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Publication number: 20210338936Abstract: A drug delivery device includes a housing defining a shell having a proximal end and a distal end and a longitudinal axis extending between the proximal end and the distal end, a needle assembly at least partially disposed within the housing at the proximal end, a drive assembly at least partially disposed within the housing and operably coupled to the needle assembly, and an audible indicator operably coupled to the drive assembly. The needle assembly includes a syringe containing a medicament and a needle or a cannula. The drive assembly is movable between an initial position and a second position that results in the medicament being expelled from the syringe. Upon the drive assembly being positioned in the second position, the audible indicator engages the drive assembly to generate an audible sound indicating the medicament has been expelled from the syringe.Type: ApplicationFiled: October 4, 2019Publication date: November 4, 2021Inventors: Jakob Halkjaer PEDERSEN, Matias MELANDER
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Publication number: 20210260302Abstract: A drug delivery device includes a housing, an injection assembly at least partially disposed in the housing, a shield, and a drive assembly at least partially disposed in the housing and coupled with the injection assembly and the shield. The shield has an extended position where at least a proximal end thereof extends a distance beyond a proximal end of the housing. The injection assembly includes a needle or cannula having an endpoint. Upon moving the shield axially towards the distal end of the housing a predetermined distance, a retraction profile commences whereby the drive assembly administers a medicament via the injection assembly. A peak resistance force is exerted within approximately the first 12 mm of axial movement of the shield.Type: ApplicationFiled: August 16, 2019Publication date: August 26, 2021Inventors: Matias Melander, Joshua Jay Dudman, Joseph Michael Iglesias, Bjarke Lykke Ludvig Svendsen, Adam B. McCullough, Christian Plambech, Steve Sanchez
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Patent number: 11097046Abstract: The invention relates to an injection device for injecting a liquid drug. The injection device comprises a housing assembly supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected and a reusable needle cannula connected to the cartridge. A needle shield assembly provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections is further provided.Type: GrantFiled: August 10, 2016Date of Patent: August 24, 2021Assignee: Novo Nordisk A/SInventors: Mie Haraldsted, Morten Revsgaard Frederiksen, Matias Melander, Christian Hoejris Nielsen, Graham Hinde, Bas Kamp, Roshan Hakkim
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Publication number: 20210093793Abstract: A drug delivery device may include a housing defining a longitudinal axis and having an opening and a drug storage container including a delivery member having an insertion end configured to extend at least partially through the opening during a delivery state. The device may also include plunger moveable toward the distal end of the drug storage container to expel a drug from the drug storage container through the delivery member, the plunger including a body portion having an inner wall defining an axial chamber and an outer wall cooperating with the inner wall to define a body thickness. The device may further include a plunger biasing member disposed at least partially within the axial chamber, the plunger biasing member configured to urge the plunger toward the distal end of the drug storage container.Type: ApplicationFiled: September 29, 2020Publication date: April 1, 2021Inventors: Emil Finkelstein, Soren Forbech Skall, Lars Eilertsen, Matias Melander, Jan Jensen
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Publication number: 20210093789Abstract: Drug delivery devices and related arrangements are disclosed. A drug delivery device may include a housing having an opening, a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening, and a plunger. A drive mechanism may be included for driving the plunger in a distal direction to expel a drug from the drug storage container through the delivery member upon activation. The drug delivery device may additionally include a guard moveably disposed adjacent to the opening and operably coupled to the drive mechanism for activation of the drive mechanism. A lock may be selectively engageable with the guard to limit movement of the guard in the proximal direction. An indicator may be coupled to the drive mechanism to generate an audible signal during drug delivery, and to cease generating the audible signal when drug delivery is complete.Type: ApplicationFiled: September 29, 2020Publication date: April 1, 2021Inventors: Christian Plambech, Matias Melander, Bjarke Lykke Ludvig Svendsen, Joshua Jay Dudman, Michael Sorensen, Margaux Frances Boyaval, Avon Kuo
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Publication number: 20200114082Abstract: A drug delivery device includes a housing defining a shell having a proximal and a distal end, a needle assembly at least partially disposed within the housing at the proximal end, a drive assembly at least partially disposed within the housing, and a damper mechanism at least partially disposed within the housing adjacent to the distal end. The housing further defines a longitudinal axis extending between the proximal end and the distal end. The needle assembly includes a syringe barrel containing a medicament and a needle or a cannula. The drive assembly is operably coupled to the needle assembly to urge the medicament through the needle or cannula. The damper mechanism is operably coupled to the drive assembly and the housing. Upon activating the drive assembly, the damper mechanism dampens an effect thereof.Type: ApplicationFiled: October 15, 2019Publication date: April 16, 2020Inventors: Matias Melander, Jakob Halkjaer Pedersen, Christian Plambech, Adam B. McCullough, Julian Jazayeri
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Publication number: 20200101229Abstract: Injection systems for drug delivery are disclosed. A system may include a container filled or fillable with a drug, a stopper movably disposed in the container, a plunger, an energy source outputting a force, a mechanical linkage operable to transmit the force output by the energy source to the plunger to cause the plunger to act on the stopper to expel the drug from the container, and a trigger member. The system may have pre-injection state where the trigger member inhibits actuation of the mechanical linkage, an injection state where the trigger member permits actuation of the mechanical linkage, and a post-injection state where the plunger is stationarily positioned in an end-of-dose position. The system may be designed to limit the number of components included in various force transmission loops present in the pre-injection, injection, and/or post-injection states.Type: ApplicationFiled: October 2, 2019Publication date: April 2, 2020Inventors: Christian Plambech, Matias Melander
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Patent number: 10406291Abstract: An autoinjector (100) for expelling a single dose of drug from a drug cartridge (600) including a piston (630), the autoinjector including: a base (200, 220), a needle (500) that is fixedly mounted relative to the base (200, 220), a plunger (310, 320, 400) adapted for cooperation with the piston (630), an actuating spring (330) provided as a helical compression spring arranged to act on the plunger (310, 320, 400) by exerting an axial force on the plunger to drive the piston (630) distally, and a needle shield (350, 380) axially movable relative to the base (200, 220) between an extended position and a collapsed position. The autoinjector defines a lock (320, 328, 380, 388) that is released when the needle shield (350, 380) is moved from the extended position to the collapsed position.Type: GrantFiled: April 7, 2015Date of Patent: September 10, 2019Assignee: Novo Nordisk A/SInventors: Soeren Kjellerup Hansen, Mads Schenstroem Stefansen, Matias Melander, Bastian Gaardsvig Kjeldsen
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Patent number: 10335536Abstract: Disclosed is a medical injection device (1) comprising a needle assembly (20) having a cannula (21) and a telescopic shield (30) for covering the distal tip (23) in a no use situation. The telescopic shield further carries a cleaning reservoir (40) for cleaning the needle cannula between two subsequent injections. The cleaning reservoir is provided with an opening (43) connecting to an overflow reservoir (51/55) such that the cleaning liquid contained in the cleaning reservoir can retract and expand upon temperature changes and does not enter the needle lumen instead. In one example, the overflow reservoir is formed as a channel (51).Type: GrantFiled: May 8, 2015Date of Patent: July 2, 2019Assignee: Novo Nordisk A/SInventors: Matias Melander, Christian Hoejris Nielsen, Mie Haraldsted
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Publication number: 20190083359Abstract: The present invention relates to a pharmaceutical adaptor system. The pharmaceutical adaptor system comprises a syringe assembly having an axial extension and comprising a first end part and a second end part, the first end part having a male tubular projection, the syringe assembly comprising a syringe and a connecting element having a first mechanical connection part, a unit such as a needle, a vial, a catheter or an IV line, and an adaptor providing fluid communication between the syringe and the unit and having a second mechanical connection part configured to engage with the first mechanical connection part in an engagement direction, thereby in fully engaged position preventing further relative axial movement between the adaptor and the male tubular projection, wherein the adaptor comprises a sealing element configured to receive the male tubular projection and provide sealing between the male tubular projection and the adaptor.Type: ApplicationFiled: February 6, 2017Publication date: March 21, 2019Inventors: Hans Stenberg Knudsen, Matias Melander, Jakob Halkjaer Pedersen
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Publication number: 20180243498Abstract: The invention relates to an injection device for injecting a liquid drug. The injection device comprises a housing assembly supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected and a reusable needle cannula connected to the cartridge. A needle shield assembly provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections is further provided.Type: ApplicationFiled: August 10, 2016Publication date: August 30, 2018Inventors: Mie Haraldsted, Morten Revsgaard Frederiksen, Matias Melander, Christian Hoejris Nielsen, Graham Hinde, Bas Kamp, Roshan Hakkim
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Patent number: D962423Type: GrantFiled: November 5, 2020Date of Patent: August 30, 2022Assignee: AMGEN INC.Inventors: Matias Melander, Bjarke Lykke Ludvig Hooge, Christian Plambech, Dylan Bourelle, Jakob Halkjaer Pedersen, Joshua J. Dudman, Emil Spork
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Patent number: D985119Type: GrantFiled: March 30, 2021Date of Patent: May 2, 2023Assignee: AMGEN INC.Inventors: Matias Melander, Bjarke Lykke Ludvig Svendsen, Christian Plambech, Michael Sorensen, Dylan Bourelle
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Patent number: D1010107Type: GrantFiled: July 29, 2022Date of Patent: January 2, 2024Assignee: AMGEN INC.Inventors: Matias Melander, Bjarke Lykke Ludvig Svendsen, Christian Plambech, Dylan Bourelle, Jakob Halkjaer Pedersen, Joshua J. Dudman, Emil Gram Spork