Patents by Inventor Matilde Guala

Matilde Guala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds with enhanced anti-tumor effects
    Patent number: 11471459
    Abstract: The compounds of formula (I) where the group —R may represent ?O or —H, are new anti-proliferative agents with remarkable anti-tumour effects in-vivo, showing in particular a wide spectrum of activities in respect of lymphomas of different origin.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: October 18, 2022
    Assignee: FONDAZIONE PER L'ISTITUTO ONCOLOGICO DI RICERCA (IOR)
    Inventors: Eugenio Gaudio, Francesco Bertoni, Natalina Pazzi, Matilde Guala
  • NEW COMPOUNDS WITH ENHANCED ANTI-TUMOR EFFECTS
    Publication number: 20210113565
    Abstract: The compounds of formula (I) where the group —R may represent ?O or —H, are new anti-proliferative agents with remarkable anti-tumour effects in-vivo, showing in particular a wide spectrum of activities in respect of lymphomas of different origin.
    Type: Application
    Filed: March 26, 2018
    Publication date: April 22, 2021
    Inventors: Eugenio Gaudio, Francesco Bertoni, Natalina Pazzi, Matilde Guala
  • Pyridazinone derivatives as phoshoinositide 3-kinases inhibitors
    Patent number: 9745308
    Abstract: Compounds of formula (I) described herein inhibit phosphoinositide 3-kinases (PI3K) and useful for the treatment of disorders associated with PI3K enzymes.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: August 29, 2017
    Assignee: CHIESI FARMACEUTICI S.p.A.
    Inventors: Matteo Biagetti, Anna Maria Capelli, Matilde Guala
  • Indolizine derivatives as phoshoinositide 3-kinases inhibitors
    Patent number: 9527869
    Abstract: Compounds of formula (I), defined herein, inhibit phosphoinositide 3-kinases (PI3K) and are useful for the treatment of disorders associated with PI3K enzymes.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: December 27, 2016
    Assignee: CHIESI FARMACEUTICI S.p.A.
    Inventors: Matteo Biagetti, Alessandro Accetta, Anna Maria Capelli, Matilde Guala, Michele Retini
  • PYRIDAZINONE DERIVATIVES AS PHOSHOINOSITIDE 3-KINASES INHIBITORS
    Publication number: 20160075710
    Abstract: Compounds of formula (I) described herein inhibit phosphoinositide 3-kinases (PI3K) and useful for the treatment of disorders associated with PI3K enzymes.
    Type: Application
    Filed: August 31, 2015
    Publication date: March 17, 2016
    Applicant: CHIESI FARMACEUTICI S.p.A.
    Inventors: Matteo BIAGETTI, Anna Maria Capelli, Matilde Guala
  • INDOLIZINE DERIVATIVES AS PHOSHOINOSITIDE 3-KINASES INHIBITORS
    Publication number: 20150361100
    Abstract: Compounds of formula (I), defined herein, inhibit phosphoinositide 3-kinases (PI3K) and are useful for the treatment of disorders associated with PI3K enzymes.
    Type: Application
    Filed: June 17, 2015
    Publication date: December 17, 2015
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Matteo BIAGETTI, Alessandro ACCETTA, Anna Maria CAPELLI, Matilde GUALA, Michele RETINI
  • Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors
    Patent number: 9024027
    Abstract: Compounds, pyridine N-oxides, and pharmaceutically acceptable salts of formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and for preventing and/or treating diseases of the respiratory tract characterized by airway obstruction, such as asthma or COPD.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: May 5, 2015
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Elisabetta Armani, Gabriele Amari, Carmelida Capaldi, Laura Carzaniga, Elena La Porta, Matilde Guala