Patents by Inventor Mats H. WIKSTROEM

Mats H. WIKSTROEM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF FINGERPRINTING THERAPEUTIC PROTEINS VIA A TWO-DIMENSIONAL (2D) NUCLEAR MAGNETIC RESONANCE TECHNIQUE AT NATURAL ABUNDANCE FOR FORMULATED BIOPHARMACEUTICAL PRODUCTS
    Publication number: 20220187398
    Abstract: Methods of fingerprinting a specific molecule in a composition using nuclear magnetic resonance (NMR) is disclosed. The disclosed NMR methods provide several modifications and improvements over existing NMR techniques. In some embodiments, the methods include applying a cycle of signal processing steps, including applying a radio frequency (RF) pulse, applying a gradient pulse having a pulse length less than or equal to 1000 ?s, and applying a water suppression technique (WET). In some embodiments, the methods further include repeating the cycle for at least 3 times to acquire an enhanced signal of the composition.
    Type: Application
    Filed: March 26, 2020
    Publication date: June 16, 2022
    Applicant: AMGEN INC.
    Inventors: Tsang-Lin HWANG, Mats H. WIKSTROEM