Patents by Inventor Mats Jernberg

Mats Jernberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR ISOLATION AND PURIFICATION OF A TARGET PROTEIN FREE OF PRION PROTEIN (PRPSC)
    Publication number: 20160152661
    Abstract: A process for isolation and purification of a target protein by chromatography wherein the chromatography removes or depletes prions (PrPSc), comprising the steps of contacting a potentially PrPSC-contaminated sample comprising a target protein with a multimodal chromatographic material; setting buffer conditions so that the target protein is bound to the multimodal chromatographic material and whereas PrPSC is not binding to the multimodal chromatographic material; followed by elution of the target protein.
    Type: Application
    Filed: December 29, 2015
    Publication date: June 2, 2016
    Inventors: Gustav GILLJAM, Mats JERNBERG, Stefan WINGE, Andrea NEISSER-SVAE
  • Process for isolation and purification of a target protein free of prion protein (PrP)
    Patent number: 9296799
    Abstract: A process for isolation and purification of a target protein by chromatography wherein the chromatography removes or depletes prions (PrPSC), comprising the steps of contacting a potentially PrPSC contaminated sample comprising a target protein with a multimodal chromatographic material; setting buffer conditions so that the target protein is bound to the multimodal chromatographic material and whereas PrPSC is not binding to the multimodal chromatographic material; followed by elution of the target protein. a process for isolation and purification of a target protein free of prion protein (prpSC).
    Type: Grant
    Filed: August 25, 2008
    Date of Patent: March 29, 2016
    Assignee: OCTAPHARMA AG
    Inventors: Gustav Gilljam, Mats Jernberg, Stefan Winge, Andrea Neisser-Svae
  • Process of purifying coagulation factor VIII
    Patent number: 8329871
    Abstract: A process of purifying or enriching coagulation FVIII employing chromatography comprising the steps of providing a fraction containing FVIII in an aqueous solution having a high ionic strength; contacting the fraction containing FVIII with a multimodal resin; optionally washing the multimodal resin having FVIII adsorbed with an aqueous washing buffer; eluting FVIII containing fractions by an aqueous elution buffer comprising at least one amino acid which is positively charged at pH 6 to 8; and optionally collecting FVIII containing fractions in purified or enriched form.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: December 11, 2012
    Assignee: Octapharma AG
    Inventors: Carin Borgvall, Ulrika Ericsson, Gustav Gilljam, Mats Jernberg, Stefan Winge
  • PROCESS OF PURIFYING COAGULATION FACTOR VIII
    Publication number: 20110160435
    Abstract: A process of purifying or enriching coagulation FVIII employing chromatography comprising the steps of providing a fraction containing FVIII in an aqueous solution having a high ionic strength; contacting the fraction containing FVIII with a multimodal resin; optionally washing the multimodal resin having FVIII adsorbed with an aqueous washing buffer; eluting FVIII containing fractions by an aqueous elution buffer comprising at least one amino acid which is positively charged at pH 6 to 8; and optionally collecting FVIII containing fractions in purified or enriched form.
    Type: Application
    Filed: June 24, 2009
    Publication date: June 30, 2011
    Inventors: Carin Borgvall, Ulrika Ericsson, Gustav Gilljam, Mats Jernberg, Stefan Winge
  • PROCESS FOR ISOLATION AND PURIFICATION OF A TARGET PROTEIN FREE OF PRION PROTEIN (PRPSC)
    Publication number: 20100210821
    Abstract: A process for isolation and purification of a target protein by chromatography wherein the chromatography removes or depletes prions (PrPSC), comprising the steps of contacting a potentially PrPSC contaminated sample comprising a target protein with a multimodal chromatographic material; setting buffer conditions so that the target protein is bound to the multimodal chromatographic material and whereas PrPSC is not binding to the multimodal chromatographic material; followed by elution of the target protein. a process for isolation and purification of a target protein free of prion protein (prpSC).
    Type: Application
    Filed: August 25, 2008
    Publication date: August 19, 2010
    Inventors: Gustav Gilljam, Mats Jernberg, Stefan Winge, Andrea Neisser-Svae