Patents by Inventor Mats Strömqvist

Mats Strömqvist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression methods
    Patent number: 6525241
    Abstract: The present invention relates to human bile salt-stimulated lipase (BSSL) obtainable from transgenic sheep. The invention further relates to transgenic sheep whose germ cells and somatic cells contain a recombinant nucleotide molecule comprising a nucleotide sequence encoding for human BSSL. The invention also relates to methods for producing said transgenic animals, as well as to methods for producing human BSSL derived from transgenic animals. In addition, the invention provides the use of compositions comprising BSSL in the treatment of diseases relating to exocrine pancreatic insufficiency, and for improvement of the utilization of dietary lipids in preterm born infants.
    Type: Grant
    Filed: July 18, 1999
    Date of Patent: February 25, 2003
    Assignee: AstraZeneca AB
    Inventors: Michael Dalrymple, Lennart Lundberg, Mats Strömqvist
  • DNA encoding human &kgr; casein and process for obtaining the protein
    Patent number: 6232094
    Abstract: The present invention relates to an expression system comprising a DNA sequence encoding a polypeptide which has a biological activity of human &kgr;-casein, the system comprising a 5′-flanking sequence capable of mediating expression of said DNA sequence. In preferred embodiments the 5′-flanking sequence is from a milk protein gene of a mammal such as a casein gene or whey acidic protein (WAP) gene and the DNA sequence contains at least one intron sequence selected from the intron sequences presented in SEQ ID NO:30. The invention also relates to DNA sequences, replicable expression vectors and cells harboring said vectors, recombinant polypeptide e.g. in glycosylated form, and milk, infant formula or nutrient supplement comprising recombinant polypeptide.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: May 15, 2001
    Assignee: Symbicom Aktiebolag
    Inventors: Lennart Hansson, Mats Strömqvist, Sven Bergström, Olle Hernell, Jan Törnell
  • Transgenic non-human mammal expressing the DNA sequence encoding kappa casein mammary gland and milk
    Patent number: 6222094
    Abstract: The present invention relates to an expression system comprising a DNA sequence encoding a polypeptide which ha a biological activity of human &kgr;-casein, the system comprising a 5′-flanking sequence capable of mediating expression of said DNA sequence. In preferred embodiments the 5′-flanking sequence is from a milk protein gene of a mammal such as a casein gene or whey acidic protein (WAP) gene and the DNA sequence contains at least one intron sequence. The invention further relates to DNA sequences, replicable expression vectors and cells harboring said vectors, recombinant polypeptide e.g. in glycosylated form, and milk, infant formula or nutrient supplement comprising recombinant polypeptide.
    Type: Grant
    Filed: December 6, 1994
    Date of Patent: April 24, 2001
    Assignee: Symbicom Aktiebolag
    Inventors: Lennart Hansson, Mats Strömqvist, Sven Bergström, Olle Hernell, Jan Törnell