Abstract: A porous microneedle capable of accessing a target portion on a surface of the skin or under the skin in a pinpoint manner, a microneedle array of the same, and a production method of the microneedle. A part of a surface of a porous needle main body is coated with a coating member. The needle main body may include a flow path inside formed to extend in a net shape. The needle main body may be formed of a porous body, and may include a flow path formed from void parts of the porous body.

Abstract: This disclosure provides a method of absorbing or discharging water of an ophthalmic medical device capable of absorbing and discharging water, and an ophthalmic medical device. The method of absorbing or discharging water of an ophthalmic medical device of the present disclosure includes using an ophthalmic medical device including a plurality of electrodes, and generating an electroosmotic flow inside and/or outside the medical device.

Abstract: A hydrogel that adheres to the surface of materials is provided by using as constituent elements a water-soluble main chain monomer, crosslinking agent, polymerization initiator, and adhesive monomer having at least a catechol group in a side chain.

Abstract: This disclosure provides an electrode body in which an electrode is firmly fixed to a gel without performing electrolytic polymerization. In the electrode body, at a least part of a surface of an electrode is uneven, at least a part of the uneven surface of the electrode is covered with a gel, the gel has a three-dimensional network structure, at least a part of the uneven surface is in contact with the three-dimensional network structure and is embedded inside the three-dimensional network structure. The electrode is preferably a laminated body in which a resin layer is laminated on both surfaces of a conductive base material. It is more preferably that the conductive base material be a fabric woven from fibers and the uneven surface be a surface of the fabric.

Abstract: A hydrogel that adheres to the surface of materials is provided by using as constituent elements a water-soluble main chain monomer, crosslinking agent, polymerization initiator, and adhesive monomer having at least a catechol group in a side chain.

Abstract: A hydrogel that adheres to the surface of materials is provided by using as constituent elements a water-soluble main chain monomer, crosslinking agent, polymerization initiator, and adhesive monomer having at least a catechol group in a side chain.

Abstract: A composite material including a substrate, a porous body provided on the substrate, and insulating polymers starting from a surface of the substrate and extending inside the porous body, and a method of producing the composite material.

Abstract: There is provided a conductive film having conductivity in a surface direction, being deformable, having excellent durability, and transmitting visible light. A conductive film includes a film substrate and a conductive material layer. The conductive material layer is provided on a first substrate surface of the film substrate. A plurality of through holes penetrating the film substrate and the conductive material layer in a thickness direction are formed in the conductive film. The conductive material layer has a plurality of conductive portions, and the conductive portions are present between adjacent layer opening portions. The number of the conductive portion is 400 per 1 mm2, and an opening ratio of the conductive material layer is at least 40%.

Abstract: An object of the present invention is to provide a composite material that may be easily delivered and mounted in the living body. The object can be solved by a coated composite material characterized in that a composite material, in which a porous body is bounded to a substrate, is coated with at least one soluble component selected from a group consisting of a water-soluble compound, a temperature-sensitive soluble compound, and a pH sensitive soluble compound.

Abstract: Disclosed are a probe including a hollow needle having an outer diameter of 0.003 to 0.4 mm and a length of 0.2 to 40 mm, wherein a distal end and a terminal end of the hollow needle are bridged with a salt bridge, an epidermal electric potential measuring device including the probe, an epidermal electric potential measuring method using the epidermal electric potential measuring device, and a cosmetic method using the epidermal electric potential measuring device.

Abstract: A composite material including a substrate, a porous body provided on the substrate, and insulating polymers starting from a surface of the substrate and extending inside the porous body, and a method of producing the composite material.

Abstract: There is provided a conductive film having conductivity in a surface direction, being deformable, having excellent durability, and transmitting visible light. A conductive film includes a film substrate and a conductive material layer. The conductive material layer is provided on a first substrate surface of the film substrate. A plurality of through holes penetrating the film substrate and the conductive material layer in a thickness direction are formed in the conductive film. The conductive material layer has a plurality of conductive portions, and the conductive portions are present between adjacent layer opening portions. The number of the conductive portion is 400 per 1 mm2, and an opening ratio of the conductive material layer is at least 40%.

Abstract: A hydrogel that adheres to the surface of materials is provided by using as constituent elements a water-soluble main chain monomer, crosslinking agent, polymerization initiator, and adhesive monomer having at least a catechol group in a side chain.

Abstract: A porous structure (1) provided with a pattern that is composed of a conductive polymer, which comprises a porous body (2) and a pattern (3) that is composed of a conductive polymer and arranged on the porous body (2). The porous body (2) is preferably a gel, and a dopant may be added to the pattern (3) that is composed of a conductive polymer. If an agarose gel is used as the gel (2) and a PEDOT electrode (3A) is used as the pattern (3) that is composed of a conductive polymer in the porous structure (1) which is provided with the pattern (3) that is composed of a conductive polymer, the porous structure (1) can be used as an electrode for cell stimulation. The porous structure (1) provided with the pattern (3) that is composed of a conductive polymer can be produced by an electropolymerization method.

Abstract: The object of the present invention is to provide an electrode member with the hydrogel substrate, capable of producing a high-voltage pulse. Further, the other object of the present invention is to provide an electrode member which is not broken due to a deformation of the hydrogel. The object can be solved by a porous substrate electrode member characterized in that an electrode is bound to a porous body by an adhesion layer of an electrically conducting polymer, and the electrode is at least one selected from a group consisting of a metallic electrode, a stretch electrode, a carbon electrode, and a composite electrode thereof.

Abstract: A drug delivery system for delivering a drug at a sustained constant rate for a long period, which can be transplanted into an affected part safely and in a simple manner and can deliver a drug to the affected part for a long period. A sustained drug delivery system in which an implant is implanted into a body, wherein the implant is a PEG capsule comprising a box-shaped PEG and a porous PEG sheet.

Abstract: The present invention answers the demands of power generating device and biosensor development and provides a flexible, free-standing type protein containing carbon nanotube film, and a sensor and power generating device each equipped with the carbon nanotube film as an electrode. According to the present invention a carbon nanotube free standing film is provided including a carbon nanotube aggregate formed by aggregating a plurality of carbon nanotubes, and a plurality of enzymes included between the plurality of carbon nanotubes. The carbon nanotube film may include a different protein to the enzyme and may include a surfactant agent between the plurality of carbon nanotubes.

Abstract: Disclosed is a drug delivery system for delivering a drug at a sustained constant rate for a long period, which can be transplanted into an affected part safely and in a simple manner and can deliver a drug to the affected part for a long period. Specifically disclosed is a sustained drug delivery system in which an implant is implanted into a body, wherein the implant is a PEG capsule comprising a box-shaped PEG and a porous PEG sheet.

Abstract: A drug delivery system for delivering a drug at a sustained constant rate for a long period, which can be transplanted into an affected part safely and in a simple manner and can deliver a drug to the affected part for a long period. A sustained drug delivery system in which an implant is implanted into a body, wherein the implant is a PEG capsule comprising a box-shaped PEG and a porous PEG sheet.

Abstract: The invention provides a method for evaluating a corneal disorder quantitatively and is applicable to living eyes. In particular, the invention provides a method for measuring a corneal transepithelial electric resistance, which method comprises: (1) a step of placing a first electrode on the cornea and a second electrode on the conjunctiva; and (2) a step of flowing an electric current between the first electrode and the second electrode to measure the electric resistance. The invention also provides a device for measuring a corneal transepithelial electric resistance value.