Abstract: A medical concept code analysis system includes a medical terminology source and at least one processor configured to access the medical terminology source. The processor also is configured to receive interface terminology concept code information associated with a plurality of interface terminology concept codes, receive public concept code information associated with a plurality of public concept codes, generate annotations for the plurality of public concept codes based on the public concept code information by determining a string and/or substring of the description associated with each public concept code contains an annotation that align with one or more predetermined annotation categories, associate the annotations with the plurality of interface terminology concept codes, and cause the interface terminology concept codes and the annotations to be output.