Abstract: A light adjustable lens illumination system comprises an illumination source, for generating a light beam; a light delivery system, for projecting the light beam onto a Light Adjustable Lens (LAL), implanted into an eye, wherein a fraction of the light beam propagates past the LAL to a retina of the eye; and a protective beam-shaper, for shaping the light beam to have an intensity pattern with a relative central intensity reduction that varies along an axis; wherein the relative central intensity reduction at the retina is greater than the relative central intensity reduction at a LAL plane.

Abstract: A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.

Abstract: A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.

Abstract: A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power; wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.

Abstract: A light adjustable lens illumination system comprises an illumination source, for generating a light beam; a light delivery system, for projecting the light beam onto a Light Adjustable Lens (LAL), implanted into an eye, wherein a fraction of the light beam propagates past the LAL to a retina of the eye; and a protective beam-shaper, for shaping the light beam to have an intensity pattern with a relative central intensity reduction that varies along an axis; wherein the relative central intensity reduction at the retina is greater than the relative central intensity reduction at a LAL plane.

Abstract: An ophthalmic system comprises a Refraction Modification System for modifying a refraction of an eye, in response to refraction modification parameters; and a Prescription Engine, for generating the refraction modification parameters for the Refraction Modification System by a Prescription Algorithm that combines one or more diagnostic factor, determined by an ophthalmic diagnostic device, and one or more patient factor.

Abstract: A color-apodized intraocular lens includes a lens center, with a center-transmittance to transmit an incident light; a lens annul us, surrounding the lens center, configured to selectively attenuate the incident light according to a radius- and wavelength-dependent annulus-transmittance, wherein the annulus-transmittance is less than the center-transmittance, in a short wavelength spectral range; and haptics, extending from the lens annulus.

Abstract: A Light Adjustable Lens (LAL) comprises a central region, centered on a central axis, having a position-dependent central optical power, and a peripheral annulus, centered on an annulus axis and surrounding the central region, having a position-dependent peripheral optical power, wherein the central optical power is at least 0.5 diopters different from an average of the peripheral optical power, and the central axis is laterally shifted relative to the annulus axis. A method of adjusting the LAL comprises implanting a LAL; applying a first illumination to the LAL with a first illumination pattern to induce a position-dependent peripheral optical power in at least a peripheral annulus, centered on an annulus axis; determining a central region and a corresponding central axis of the LAL; and applying a second illumination to the LAL with a second illumination pattern to induce a position-dependent central optical power in the central region of the LAL.

Abstract: A color-apodized intraocular lens includes a lens center, with a center-transmittance to transmit an incident light; a lens annul us, surrounding the lens center, configured to selectively attenuate the incident light according to a radius- and wavelength-dependent annulus-transmittance, wherein the annulus-transmittance is less than the center-transmittance, in a short wavelength spectral range; and haptics, extending from the lens annulus.

Abstract: An implantable microstimulator includes a plastic housing having a first end and a second end; an electronic subassembly disposed within the housing; a first electrode disposed at the first end of the plastic housing and in electrical communication with the electronic subassembly; and a second electrode disposed at the second end of the plastic housing and in electrical communication with the electronic subassembly. The plastic housing, first electrode, and second electrode form a hermetically sealed structure around the electronic subassembly.