Abstract: An air treatment system comprises an air conditioner; a bipolar ionization assembly; and a power supply. The air conditioner may portable and include a wheeled housing; an evaporator or entry grill for ambient air; a condenser grill for hot air discharge; a cold air supply discharge grate; a motor; an evaporator coil; and an evaporator blower intake. The bipolar ionization assembly includes electrical leads, and is mounted by a bracket to the evaporator blower intake to position the electrical leads within the air stream of the evaporator blower intake. The power supply is operably connected to the portable air conditioner and to the bipolar ionization assembly. When mounted in the air conditioner, the bipolar ionization assembly creates an antimicrobial plasma capable of killing harmful pathogens including bacteria, mycoplasma, viruses, mold and odors, and reducing the presence of Volatile Organic Compounds (VOC's), particulates, and static electricity in the air.