Abstract: The present disclosure is directed to compositions, devices, a system, and related methods for treatment of skin. The subject matter of the present disclosure also provides maintenance treatment, acne treatment, rejuvenation treatment, and anti-aging treatment for skin. In accordance with some aspects, a photodynamic skin therapy system may generally comprise an apparatus supporting light emissive panels which may in some situations be configured and operative to be coupled to a remote or external device. The light emissive panels may emit light of a selected wavelength in accordance with instructions defining a skin treatment regimen.