Patents by Inventor Matt SIMON

Matt SIMON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL MOLECULE INHIBITORS OF PR3 AND HNE AND USES THEREOF
    Publication number: 20250051286
    Abstract: Disclosed herein are novel small molecules that can be used therapeutically to treat ailments and diseases associated with an over-active or undesired immune response. Specific embodiments include inhibitors of Proteinase 3 (PR3) and Human Neutrophil Elastase (HNE) and methods for their synthesis and use. The agents can be used to treat alpha-1 antitrypsin deficiency and other ailments related to neutrophil activity.
    Type: Application
    Filed: December 16, 2022
    Publication date: February 13, 2025
    Applicant: ORIXA THERAPEUTICS LLC
    Inventors: Adam Seth HAEBERLE, Matteo PANZA, James Bernard KRAMER, Zahra ASSAR-NOSSONI, Matt SIMON