Abstract: Cooling or refrigeration systems, and methods of operating same, are disclosed herein. In one example embodiment, such a system includes a first and second high stage circuits each including a respective heat exchanger and a respective condenser that are coupled together at least indirectly so as to allow a respective portion of a first coolant to cycle therebetween. The system also includes a low stage circuit including a heat transfer device that is coupled at least indirectly with each of the heat exchangers, so as to allow an additional portion of a second coolant to cycle between the at least one evaporator and the heat exchangers, and in a parallel manner such that, if a first one of the high stage circuits ceases operating at a desired level, then the system can continue to operate by way of a second one of the high stage circuits.

Abstract: Coronary access and delivery systems are provided. A coronary access system can include a coronary sinus guide and a first core. A lateral vein delivery system can include a lateral vein introducer and a second core. The coronary sinus guide, the lateral vein introducer, and the first and second cores may be designed or shaped to access a predetermined position within a heart of a subject. For example, the coronary sinus guide, the lateral vein introducer, and/or the first and second cores can be used in combination to access the predetermined position within the heart of the subject.

Abstract: Cooling or refrigeration systems, and methods of operating same, are disclosed herein. In one example embodiment, such a system includes a first and second high stage circuits each including a respective heat exchanger and a respective condenser that are coupled together at least indirectly so as to allow a respective portion of a first coolant to cycle therebetween. The system also includes a low stage circuit including a heat transfer device that is coupled at least indirectly with each of the heat exchangers, so as to allow an additional portion of a second coolant to cycle between the at least one evaporator and the heat exchangers, and in a parallel manner such that, if a first one of the high stage circuits ceases operating at a desired level, then the system can continue to operate by way of a second one of the high stage circuits.

Abstract: Coronary access and delivery systems are provided. A coronary access system can include a coronary sinus guide and a first core. A lateral vein delivery system can include a lateral vein introducer and a second core. The coronary sinus guide, the lateral vein introducer, and the first and second cores may be designed or shaped to access a predetermined position within a heart of a subject. For example, the coronary sinus guide, the lateral vein introducer, and/or the first and second cores can be used in combination to access the predetermined position within the heart of the subject.