Abstract: A process for three-dimensional shaping of a biological and/or artificial tissue/tissue component. The process is consistent for shaping tissues and can produce a desired three-dimensional and permanent shaping of the tissue/tissue component via crosslinking. A suitable crosslinking agent is used in combination with shaped body and a granulate.

Abstract: A medical implant, such as a transcatheter deliverable endoprosthesis or a prosthetic heart valve including a stent-structure, one or more skirts and optionally a valve assembly. One or more skirts and/or the one or more leaflets include one or more laser markings that partially or fully penetrate a thickness of the one or more skirts and/or the one or more leaflets. The laser marks are preferably sufficiently big to be optically visible at the surface of the outer skirt by an operator during a sewing process. Each laser marking may be used for suturing, wherein the reduced material thickness eases the suturing/sewing process without compromising the structural integrity of the material of the outer skirt (e.g.

Abstract: A vascular implant, in particular a prosthetic heart valve, for providing valve function, has a stent structure with a proximal conical-convex inflow region, a distal, linear cylindrical outflow region, an intermediate transition region, and a corresponding valve arrangement. When the stent structure is in the expanded state, a higher maximum radial force exists in the inlet region in direct comparison to the lower maximum radial force in the outlet region and in the transition region.