Patents by Inventor Matteo Conza

Matteo Conza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for preparing a pan-JAK inhibitor and related intermediate compounds
    Patent number: 11739103
    Abstract: The present disclosure provides processes for preparing a crystalline form of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile and related intermediate compounds.
    Type: Grant
    Filed: October 7, 2021
    Date of Patent: August 29, 2023
    Assignee: Theravance Biopharma R&D LP, LLC
    Inventors: Norbert Kraut, Matteo Conza, Anja Huste, Vit Lellek, Bjorn Gielen, Christian Pater, Dimitar Filipov, Xiaojun Huang, Stephen Roseblade
  • PROCESSES FOR PREPARING A PAN-JAK INHIBITOR AND RELATED INTERMEDIATE COMPOUNDS
    Publication number: 20220112219
    Abstract: The present disclosure provides processes for preparing a crystalline form of 3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile and related intermediate compounds.
    Type: Application
    Filed: October 7, 2021
    Publication date: April 14, 2022
    Inventors: Norbert Kraut, Matteo Conza, Anja Huste, Vit Lellek, Bjorn Gielen, Christian Pater, Dimitar Filipov, Xiaojun Huang, Stephen Roseblade
  • Substituted 2-[3-(1-methyl-piperidin-4-yl)-propylamino]-pyrimidine-5-carboxylic acids and amides and methods of making the same
    Patent number: 10100035
    Abstract: The present invention relates to certain intermediates useful in the preparation of certain benzoimidazol-2-yl pyrimidines and processes for preparing them.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: October 16, 2018
    Assignee: Janssen Pharmaceutica NV
    Inventors: Diego Broggini, Matteo Conza, Oliver Flögel, Stefan Horns, Susanne Lochner, Guangrong Tang, Zhaobin Wang, Lucie Lovelle
  • SUBSTITUTED 2-[3-(1-METHYL-PIPERIDIN-4-YL)-PROPYLAMINO]-PYRIMIDINE-5-CARBOXYLIC ACIDS AND AMIDES AND METHODS OF MAKING THE SAME
    Publication number: 20180009783
    Abstract: The present invention relates to certain intermediates useful in the preparation of certain benzoimidazol-2-yl pyrimidines and processes for preparing them.
    Type: Application
    Filed: September 20, 2017
    Publication date: January 11, 2018
    Inventors: Diego Broggini, Matteo Conza, Oliver Flögel, Stefan Horns, Susanne Lochner, Guangrong Tang, Zhaobin Wang, Lucie Lovelle
  • Substituted 2-[3-(1-methyl-piperidin-4-yl)-propylamino]-pyrimidine-5-carboxylic acids and amides and methods of making the same
    Patent number: 9796699
    Abstract: The present invention relates to certain intermediates useful in the preparation of certain benzoimidazol-2-yl pyrimidines and processes for preparing them.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: October 24, 2017
    Assignee: Janssen Pharmaceutica NV
    Inventors: Diego Broggini, Matteo Conza, Oliver Flögel, Stefan Horns, Susanne Lochner, Guangrong Tang, Zhaobin Wang, Lucie Lovelle
  • Process for the preparation of opioid compounds
    Patent number: 9701688
    Abstract: The present invention is directed to a process for the preparation of opioid compounds such as buprenorphine, naltrexone, naloxone, nalbuphone, nalbuphine, and the like.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: July 11, 2017
    Assignee: NORAMCO, INC.
    Inventors: Matteo Conza, Vit Lellek, Hartmut Zinser
  • Benzoimidazol-2-yl pyrimidine modulators of the histamine Hreceptor
    Patent number: 9663497
    Abstract: Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: May 30, 2017
    Assignee: Janssen Pharmaceutica NV
    Inventors: Matteo Conza, Magali B. Hickey, Stefan Horns, Susanne Lochner
  • SUBSTITUTED 2-[3-(1-METHYL-PIPERIDIN-4-YL)-PROPYLAMINO]-PYRIMIDINE-5-CARBOXYLIC ACIDS AND AMIDES AND METHODS OF MAKING THE SAME
    Publication number: 20170121309
    Abstract: The present invention relates to certain intermediates useful in the preparation of certain benzoimidazol-2-yl pyrimidines and processes for preparing them.
    Type: Application
    Filed: November 2, 2016
    Publication date: May 4, 2017
    Inventors: Diego Broggini, Matteo Conza, Oliver Flögel, Stefan Horns, Susanne Lochner, Guangrong Tang, Zhaobin Wang, Lucie Lovelle
  • BENZOIMIDAZOL-2-YL PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
    Publication number: 20160340337
    Abstract: Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.
    Type: Application
    Filed: August 3, 2016
    Publication date: November 24, 2016
    Inventors: Matteo Conza, Magali B. Hickey, Stefan Horns, Susanne Lochner
  • Benzoimidazol-2-yl pyrimidine modulators of the histamine Hreceptor
    Patent number: 9434715
    Abstract: Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: September 6, 2016
    Assignee: Janssen Pharmaceutica NV
    Inventors: Matteo Conza, Magali B. Hickey, Stefan Horns, Susanne Lochner
  • BENZOIMIDAZOL-2-YL PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
    Publication number: 20160159775
    Abstract: Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.
    Type: Application
    Filed: February 18, 2016
    Publication date: June 9, 2016
    Inventors: Matteo Conza, Magali B. Hickey, Stefan Horns, Susanne Lochner
  • Benzoimidazol-2-yl pyrimidine modulators of the histamine Hreceptor
    Patent number: 9278952
    Abstract: Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: March 8, 2016
    Assignee: JANSSEN PHARMACEUTICA NV
    Inventors: Matteo Conza, Magali B. Hickey, Stefan Horns, Susanne Lochner
  • PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT
    Publication number: 20150376193
    Abstract: Disclosed is a process for the preparation of the following compounds: where R1, R1a and R2a have the definitions in the description, as well as a process to prepare other intermediates that may be useful to synthesise downstream products, especially compounds that are useful as medicaments, for instance Bruton's tyrosine kinase (Btk) inhibitors such as ibrutinib. Also disclosed are other processes, other intermediates and compounds per se.
    Type: Application
    Filed: September 9, 2015
    Publication date: December 31, 2015
    Inventors: Philip PYE, Cyril BEN HAIM, Matteo CONZA, Ioannis Nicolaos HOUPIS
  • PROCESS FOR THE PREPARATION OF OPIOID COMPOUNDS
    Publication number: 20150315205
    Abstract: The present invention is directed to a process for the preparation of opioid compounds such as buprenorphine, naltrexone, naloxone, nalbuphone, nalbuphine, and the like.
    Type: Application
    Filed: April 17, 2015
    Publication date: November 5, 2015
    Inventors: Matteo Conza, Vit Lellek, Hartmut Zinser
  • Processes and intermediates for preparing a medicament
    Patent number: 9156847
    Abstract: Disclosed is a process for the preparation of the following compounds: where R1, R1a and R2a have the definitions in the description, as well as a process to prepare other intermediates that may be useful to synthesize downstream products, especially compounds that are useful as medicaments, for instance Bruton's tyrosine kinase (Btk) inhibitors such as ibrutinib. Also disclosed are other processes, other intermediates and compounds per se.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: October 13, 2015
    Assignee: Janssen Pharmaceutica NV
    Inventors: Philip Pye, Cyril Ben Haim, Matteo Conza, Ioannis Nicolaos Houpis
  • BENZOIMIDAZOL-2-YL PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
    Publication number: 20140364607
    Abstract: Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.
    Type: Application
    Filed: August 21, 2014
    Publication date: December 11, 2014
    Inventors: Matteo Conza, Magali B. Hickey, Stefan Horns, Susanne Lochner
  • Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor
    Patent number: 8859575
    Abstract: Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: October 14, 2014
    Assignee: Janssen Pharmaceutica NV
    Inventors: Matteo Conza, Magali B. Hickey, Stefan Horns, Susanne Lochner
  • PROCESSES AND INTERMEDIATES FOR PREPARING A MEDICAMENT
    Publication number: 20140275126
    Abstract: Disclosed is a process for the preparation of the following compounds: where R1, R1a and R2a have the definitions in the description, as well as a process to prepare other intermediates that may be useful to synthesise downstream products, especially compounds that are useful as medicaments, for instance Bruton's tyrosine kinase (Btk) inhibitors such as ibrutinib. Also disclosed are other processes, other intermediates and compounds per se.
    Type: Application
    Filed: March 11, 2014
    Publication date: September 18, 2014
    Inventors: Philip PYE, Cyril BEN HAIM, Matteo CONZA, Ioannis Nicolaos HOUPIS
  • Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor
    Publication number: 20140256942
    Abstract: Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.
    Type: Application
    Filed: March 6, 2014
    Publication date: September 11, 2014
    Applicant: Janssen Pharmaceutica NV
    Inventors: Matteo Conza, Magali B. Hickey, Stefan Horns, Susanne Lochner