Patents by Inventor Matteo D'Anello

Matteo D'Anello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolo[2,3-B]pyridine derivatives active as kinase inhibitors
    Patent number: 7888508
    Abstract: Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: February 15, 2011
    Assignee: Pfizer Italia S.r.l.
    Inventors: Barbara Salom, Matteo D'Anello, Maria Gabriella Brasca, Patrizia Giordano, Katia Martina, Dania Tesei, Frederick Arthur Brookfield, William John Trigg, Edward Andrew Boyd, Jonathan Anthony Larard
  • Pyrrolo[2,3-b]Pyridine Derivatives Active as Kinase Inhibitors and Pharmaceutical Compositions Comprising Them
    Publication number: 20100210476
    Abstract: Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
    Type: Application
    Filed: April 23, 2010
    Publication date: August 19, 2010
    Applicant: PFIZER ITALIA S.R.L.
    Inventors: Barbara Salom, Matteo D'Anello, Maria Gabriella Brasca, Patrizia Giordano, Katia Martina, Francesco Angelucci, Frederick Arthur Brookfield, William John Trigg, Edward Andrew Boyd, Jonathan Anthony Larard
  • Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors and pharmaceutical compositions comprising them
    Patent number: 7728140
    Abstract: Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: June 1, 2010
    Assignee: Pfizer Italia S.r.l.
    Inventors: Barbara Salom, Matteo D'Anello, Maria Gabriella Brasca, Patrizia Giordano, Katia Martina, Francesco Angelucci, Frederick Arthur Brookfield, William John Trigg, Edward Andrew Boyd, Jonathan Anthony Larard
  • Aminoindazole derivatives active as kinase inhibitors
    Patent number: 7511136
    Abstract: Compounds which are 3-aminoindazole derivatives or pharmaceutically acceptable salts thereof, together with pharmaceutical compositions comprising them are disclosed; these compounds or compositions are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: March 31, 2009
    Assignee: Pfizer Italia S.r.l.
    Inventors: Raffaella Amici, Matteo D'Anello, Katia Martina, Barbara Salom, Anna Vulpetti
  • Heterobicyclic pyrazole derivatives as kinase inhibitors
    Patent number: 7485661
    Abstract: Bicyclo-pyrazoles of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
    Type: Grant
    Filed: January 18, 2005
    Date of Patent: February 3, 2009
    Assignee: Pfizer Italia S.r.l.
    Inventors: Roberto Tonani, Simona Bindi, Daniele Fancelli, Valeria Pittala′, Matteo D'Anello
  • Heterobicyclic pyrazole derivatives as kinase inhibitors
    Publication number: 20060160874
    Abstract: Bicyclo-pyrazoles of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
    Type: Application
    Filed: January 18, 2005
    Publication date: July 20, 2006
    Applicant: Pharmacia Italia S.p.A.
    Inventors: Roberto Tonani, Simona Bindi, Daniele Fancelli, Valeria Pittala', Matteo D' Anello
  • Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
    Publication number: 20050256151
    Abstract: Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
    Type: Application
    Filed: December 23, 2004
    Publication date: November 17, 2005
    Applicant: Pharmacia Italia S.p.A.
    Inventors: Barbara Salom, Matteo D'Anello, Maria Brasca, Patrizia Giordano, Katia Martina, Francesco Angelucci, Frederick Brookfield, William Trigg, Edward Boyd, Jonathan Larard
  • Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
    Publication number: 20050209269
    Abstract: Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
    Type: Application
    Filed: December 23, 2004
    Publication date: September 22, 2005
    Applicant: Pharmacia Italia S.p.A.
    Inventors: Barbara Salom, Matteo D'Anello, Maria Brasca, Patrizia Giordano, Katia Martina, Dania Tesei, Frederick Brookfield, William Trigg, Edward Boyd, Jonathan Larard
  • Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
    Publication number: 20040254177
    Abstract: Compounds which are 3-aminoindazole derivatives or pharmaceutically acceptable salts thereof, together with pharmaceutical compositions comprising them are disclosed; these compounds or compositions are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders.
    Type: Application
    Filed: March 22, 2004
    Publication date: December 16, 2004
    Inventors: Raffaella Amici, Matteo D'Anello, Katia Martina, Barbara Salom, Anna Vulpetti
  • Process for preparing carboxamido-4-azasteroids
    Patent number: 6284887
    Abstract: A process for producing a compound of formula (I): wherein the dotted lines - - - independently represent a single or double bond and R, R1, R2 and R3 are each hydrogen or an organic radical, comprises treating the corresponding 17&bgr;-carbonylimidazole intermediates with anhydrous acids in the presence of an amine and, optionally, hydrogenating the resulting compound.
    Type: Grant
    Filed: June 6, 2000
    Date of Patent: September 4, 2001
    Assignee: Pharmacia & Upjohn SpA
    Inventors: Achille Panzeri, Matteo D'Anello, Antonio Longo, Marcella Nesi
  • Process for preparing carboxamido-4-azasteroids
    Patent number: 6121449
    Abstract: A process for producing a compound of formula (I): ##STR1## wherein the dotted lines - - - independently represent a single or double bond and R, R.sub.1, R.sub.2 and R.sub.3 are each hydrogen or an organic radical, comprises treating the corresponding 17.beta.-carbonylimidazole intermediates with anhydrous acids in the presence of an amine and, optionally, hydrogenating the resulting compound.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: September 19, 2000
    Assignee: Pharmacia & Upjohn SpA
    Inventors: Achille Panzeri, Matteo D'Anello, Antonio Longo, Marcella Nesi
  • Process for the preparation of 7 alpha-alkoxycephem derivatives
    Patent number: 5254680
    Abstract: There is provided a process for preparing a compound of the formula (I): ##STR1## wherein R.sub.1 is an organic residue, R.sub.2 is a hydrogen or a chlorine atom, a methoxy, ethoxy or an acetoxy group, and n represents 0, 1 or 2.The process comprises reacting a compound of the formula (II): ##STR2## wherein R.sub.2 and n are as defined above, with an inorganic or organic nitrite, in an alcohol R.sub.1 OH, wherein R.sub.1 is as defined above, or in a mixture R.sub.1 OH-organic solvent in the presence of an inorganic or organic acid.The compounds of the formula (I) are known intermediates in the synthesis of human leucocyte elastase inhibitors (HLE).
    Type: Grant
    Filed: April 25, 1991
    Date of Patent: October 19, 1993
    Assignee: Farmitalia Carlo Erba S.r.l.
    Inventors: Marco Alpegiani, Pierluigi Bissolino, Matteo D'Anello, Ettore Perrone
  • Process for the preparation of 4-amino-unsaturated androstanedione derivatives
    Patent number: 5241090
    Abstract: 4-amino-unsaturated androstanedione derivatives provided with aromatase inhibitory activity are obtained by hydrolyzation of a corresponding compound of formula II ##STR1##
    Type: Grant
    Filed: May 20, 1992
    Date of Patent: August 31, 1993
    Assignee: Farmitalia Carlo Erba S.R.L.
    Inventors: Fabrizio Orzi, Antonio Longo, Matteo D'Anello, Natale Barbugian