Patents by Inventor Matteo Zanella

Matteo Zanella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reprogramming-based models of neurodevelopmental disorders and uses thereof
    Patent number: 11369577
    Abstract: The present invention relates to iPSC produced from fibroblast obtained from a subject affected by a neurodevelopmental disorder entailing intellectual disability (ID) and/or a disorder belonging to the Autism Spectrum Disorder (ASD) and/or Schizophrenia (SZ) and uses thereof. The present invention also relates to a cortical neural progenitor cell or a terminally differentiated cortical glutamatergic or gabaergic neuronal cell or a neural crest stem cell line, a mesenchymal stem cell line produced from the iPSC or iPSC line. The invention also relates to method for identifying a compound for the treatment and/or prevention of a neurodevelopmental disorder entailing intellectual disability (ID) and/or a disorder belonging to the Autism Spectrum Disorder (ASD) and/or Schizophrenia (SZ) and to a LSD1 inhibitor or a HDAC2 inhibitor for use in the treatment of such disorders.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: June 28, 2022
    Assignees: IEO—Istituto Europeo di Oncologia S.r.l., I.R.C.C.S. “Casa Sollievo della Sofferenza”, Università degli Studi di Milano
    Inventors: Giuseppe Testa, Sina Atashpazgargari, Antonio Adamo, Pierre-Luc Germain, Giuseppe Merla, Giuseppe D'Agostino, Matteo Zanella
  • Linear actuator comprising a shape memory alloy coil spring operating at low electrical power
    Patent number: 11333133
    Abstract: The present invention relates to linear actuators comprising an electrically-controlled shape memory alloy coil spring (23) suitable to provide linear displacements in valves, switches, lock systems and provided with a crimped terminal at each extremity, each of said crimped terminals comprising a crimping component (21) and an engaging member (22) suitable to mount the spring (23) into the linear actuator. The invention further discloses the use of said spring (23) with particular geometrical characteristics and crimping system assuring the maximization of the available stroke and fatigue life, structural simplicity, low electrical power requirements and thermal inertia, small size.
    Type: Grant
    Filed: March 27, 2020
    Date of Patent: May 17, 2022
    Assignee: SAES GETTERS S.P.A.
    Inventors: Marco Citro, Luca Fumagalli, Matteo Zanella, Michele Scarlata
  • LINEAR ACTUATOR COMPRISING A SHAPE MEMORY ALLOY COIL SPRING OPERATING AT LOW ELECTRICAL POWER
    Publication number: 20220042498
    Abstract: The present invention relates to linear actuators comprising an electrically-controlled shape memory alloy coil spring (23) suitable to provide linear displacements in valves, switches, lock systems and provided with a crimped terminal at each extremity, each of said crimped terminals comprising a crimping component (21) and an engaging member (22) suitable to mount the spring (23) into the linear actuator. The invention further discloses the use of said spring (23) with particular geometrical characteristics and crimping system assuring the maximization of the available stroke and fatigue life, structural simplicity, low electrical power requirements and thermal inertia, small size.
    Type: Application
    Filed: March 27, 2020
    Publication date: February 10, 2022
    Applicant: SAES GETTERS S.P.A.
    Inventors: Marco CITRO, Luca FUMAGALLI, Matteo ZANELLA, Michele SCARLATA
  • REPROGRAMMING-BASED MODELS OF NEURODEVELOPMENTAL DISORDERS AND USES THEREOF
    Publication number: 20190022027
    Abstract: The present invention relates to iPSC produced from fibroblast obtained from a subject affected by a neurodevelopmental disorder entailing intellectual disability (ID) and/or a disorder belonging to the Autism Spectrum Disorder (ASD) and/or Schizophrenia (SZ) and uses thereof. The present invention also relates to a cortical neural progenitor cell or a terminally differentiated cortical glutamatergic or gabaergic neuronal cell or a neural crest stem cell line, a mesenchymal stem cell line produced from the iPSC or iPSC line. The invention also relates to method for identifying a compound for the treatment and/or prevention of a neurodevelopmental disorder entailing intellectual disability (ID) and/or a disorder belonging to the Autism Spectrum Disorder (ASD) and/or Schizophrenia (SZ) and to a LSD1 inhibitor or a HDAC2 inhibitor for use in the treatment of such disorders.
    Type: Application
    Filed: November 25, 2015
    Publication date: January 24, 2019
    Inventors: Giuseppe Testa, Sina Atashpazgargari, Antonio Adamo, Pierre-Luc Germain, Giuseppe Merla, Giuseppe D'Agostino, Matteo Zanella