Abstract: There is disclosed a method for treating an isolated hydrocarbon interval feedable through a production tubing inside a well bore and forming an annulus therebetween. A perforated cylindrical tool having an expandable annular seal may attach to the production tubing and house a slidable element positionally responsive to an injection velocity of a well fluid. The tool may be lowered to a sealing depth for bracketing the hydrocarbon interval. Injection of the well fluid may drag a narrowing bore of the slidable element downward for expanding the annular seal against the well bore. The well fluid may also be directed from the element bore to the annulus by aligning an element flow port with a corresponding tool passage, a downstream or an upstream flow being selectable by an injection velocity for slidably aligning the corresponding flow ports having different axial locations.

Abstract: A power module assembly includes a frame assembly and a bus bar assembly. The frame assembly includes an upper frame body and a lower frame body coupled to the upper frame body, at least one of the upper and lower frame bodies including at least one jet orifice formed therethrough, the jet orifice configured to receive coolant at a first end and discharge the coolant at a second end, the upper and lower frame bodies at least partially defining a chamber therebetween. The bus bar assembly is arranged in the chamber and includes a bus bar arranged adjacent to the second end of the jet orifice. The jet orifice is configured to discharge the coolant directly onto the bus bar so as to reduce an operating temperature of the bus bar.

Abstract: An illuminated suction device comprising a suction tube having a proximal end and a distal tip at a distal end thereof, an illumination assembly comprising at least one direct light source mounted on a flexible circuit and configured to emit light toward a target area external to the distal tip of the suction tube, and at least one heat sinking member extending along a portion of the suction tube, wherein the at least one light source mounted on the flexible circuit is mechanically and thermally connected to the at least one heat sinking member.

Abstract: Composite materials and devices including composite materials are disclosed. Exemplary composite materials include a porous material and ferroelectric nematic liquid crystal within pores of the porous material. The composite materials can be used in a variety of applications, such as capacitors, information storage and processing, actuators, sensors, electro-caloric devices, energy storage and/or conversion devices utilizing piezoelectric effects. The porous material can be a solid, a polymer, glassy, crystalline, amorphous, foam, an aerogel or ceramic.

Abstract: Disclosed herein are salts and solid forms of 4-hydroxy-N,N-diisopropyltryptamine hemi-glutarate (4-OH-DIPT), e.g., 4-OH-DIPT hemi-glutarate, 4-OH-DIPT hemi-succinate, 4-OH-DIPT hemi-succinate hydrochloride, and 4-OH-DIPT hemi-glutarate hydrochloride. The solid form may be a salt and/or a crystalline form of the 4-OH-DIPT, such as a polymorph of 4-OH-DIPT or a salt thereof. Also disclosed are methods for making the solid forms and methods for administering the solid forms. The disclosed solid forms of 4-OH-DIPT are useful for treating neurological disease and/or a psychiatric disorder in a subject.

Abstract: Described herein are isotopically enriched analogs of methylone (e.g., deuterated analogs of methylone (e.g., (S)-methylone and (R)-methylone) with improved characteristics. Also described herein are salts (such as hydrochloride salt) and solid forms (e.g., crystalline forms) of methylone. Also described herein are stereoisomers (e.g., enantiomers) of methylone. The present disclosure also provides methods of making and methods of use of the methylone or methylone analogs and solid forms of 3,4-methylenedioxy-N-ethylcathinone hydrochloride described herein to treat brain and neurological disorders such as depression.

Abstract: An example system includes a motor/generator selectively coupled to a drive line of a vehicle, and configured to selectively modulate power transfer between an electrical load and the drive line; a battery pack; a DC/DC converter electrically interposed between the motor/generator and the electrical load, and between the battery pack and the electrical load; a covering tray positioned over a plurality of batteries of the battery pack, the covering tray comprising a connectivity layer that has a charging circuit allowing each of the plurality of batteries to be discharged individually; a plurality of battery microcontrollers, each of the plurality of battery microcontrollers associated with a corresponding one of a plurality of batteries of the battery pack; and a primary DC/DC controller configured to command operations of the DC/DC converter; wherein the plurality of battery microcontrollers are operationally coupled to the primary DC/DC controller.

Abstract: The invention provides aza-heterocyclyl carboxamide and related compounds, pharmaceutical compositions, and their use in the treatment of medical conditions, such as bacterial infections, and in inhibiting LpxC activity.

Abstract: The present disclosure relates to compound Formula (I) methods for making the compounds and methods for their use.

Abstract: Provided herein is a two-component polyurethane adhesive composition.

Abstract: An example system for estimating a hydration level of an individual can include: a mechanism configured to apply mechanical pressure to a digit of the individual; an light detector configured to sense the light from the digit; and a controller programmed to perform functions including: send a first signal to the mechanism to apply the mechanical pressure to the digit; send a second signal to the mechanism to release the mechanical pressure on the digit; determine a capillary refill time based upon a third signal from the light detector indicating an amount of time for capillaries of the individual to refill with blood; and estimate the hydration level of the individual based upon the capillary refill time and one or more additional parameters.

Abstract: Disclosed herein are isotopically enriched compounds and methods of using both isotopically and non-isotopically enriched compounds of the following formula in the treatment of neurologic and brain disorders/conditions.

Abstract: Provided herein is a method for transferring a material from a first substrate to a second substrate via a flexible intermediate substrate comprising a support layer and a metallic adhesion layer. The method comprises lifting the material from the first substrate with the intermediate substrate, the lifting comprising adhering the material to the metallic adhesion layer by Van der Waals adhesion between the material and the metallic adhesion layer. The method comprises depositing the material from the intermediate substrate on to the second substrate, the depositing comprising adhering the material to the second substrate by Van der Waals adhesion between the material and the second substrate. Also provided herein is a method of forming a heterostructure by removing material from one or more substrates via a flexible intermediate substrate comprising a support layer and metallic adhesion layer. A flexible substrate for performing the same is also provided.

Abstract: The present invention relates to downhole tool assemblies (50) for use in deploying an alloy plug (61) or seal within a target region of an oil/gas well and clearing/removing well structures from said target regions. The assemblies are provided with a gas-generating chemical heating mixture (58, 59, 60). The heat generated by the chemical heating mixture is employed in heating a downhole target region, while the gas generated is harness to actuate the operation of one or more functional components (54) provided on the assembly to achieve the assembly's particular down-hole operation.

Abstract: A robotic cell calibration method comprising a robotic cell system having elements comprising: one or more cameras, one or more sensors, components, and a robotic arm. The method comprises localizing positions of the one or more cameras and components relative to a position of the robotic arm using a common coordinate frame, moving the robotic arm in a movement pattern, and using the cameras and sensors to determine robotic arm position at multiple times during the movement. The method includes identifying a discrepancy in robotic arm position between a predicted position and the determined position in real time, and computing, by an auto-calibrator, a compensation for the identified discrepancy, the auto-calibrator solving for the elements in the robotic cell system as a system. The method includes modifying actions of the robotic arm in real time during the movement based on the compensation.

Abstract: A method for developing a remote command data package for a motor vehicle by a central electronic computing device involves the central electronic computing device providing a plurality of templates in a user interface of the central electronic computing device. A single template defines at least one generalized vehicle command. A developer of the remote command data package provides a workflow defining logic for the remote command data package using the user interface. The developer provides the workflow using at least one template of the plurality of templates and the central electronic computing device transforms the workflow into the vehicle command depending on the used template.

Abstract: A rooftop air conditioning unit (RTU) is disclosed. The RTU comprises an absorber configured in a supply airstream, a desorber configured in a regeneration airstream, wherein the desorber is fluidically connected to the absorber via a liquid desiccant system and an interchange heat exchanger. The RTU further comprises a first heat exchanger configured upstream of the absorber in the supply air stream, a second heat exchanger configured upstream of the desorber in the regeneration airstream, wherein the first heat exchanger is fluidically connected to the second heat exchanger via a vapor compression system, and one or more secondary heat exchanger configured between the vapor compression system and the liquid desiccant system, wherein the one or more secondary heat exchangers are operable to control temperature of a desiccant associated with the liquid desiccant system into the absorber and/or into the desorber.

Abstract: A system and method for managing climate in a premises is disclosed. The method includes receiving from a detection means, during a plurality of time periods, signals indicative of one or more persons within the premises; extracting from the received signals, identity of the one or more persons within the premises; receiving, from the one or more persons, respective preferred parameters for climate in the premises; predicting, based on the received signals during the plurality of time periods, presence of one or more persons in a subsequent time period, the corresponding identities of the one or more persons, and the respective preferred parameters for climate in the premises; and operating a climate control unit of the premises, such that, for the subsequent time period, the climate in the premises substantially corresponds with the respective preferred parameters for climate in the premises, of the one or more persons predicted to be in the premises.

Abstract: Provided are embodiments for a system for providing component control over a two-wire connection. The embodiments can include a control unit connected to a power source, a remote unit coupled to the control unit over the two-wire connection, the two-wire connection including a power/communication wire and a common wire, and a bridge-type amplifier configured to receive a power signal from the remote unit, the bridge-type amplifier configured to generate a square wave from the power signal. Also provided are embodiments for a method for providing component control over a two-wire connection.

Abstract: A heating, ventilation, and air conditioning (HVAC) system includes a housing, a plurality of compressors, a condenser, a reheater, and an evaporator arranged in fluid communication. The condenser and the reheater are arranged in parallel and the plurality of compressors are arranged in parallel. A fluid management system is operable to actively manage a flow of a fluid within the HVAC system provided to the reheater.