Patents by Inventor Matthew A. Parker

Matthew A. Parker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7601332
    Abstract: The invention describes a vitamin receptor binding drug delivery conjugate, and preparations therefor. The drug delivery conjugate consists of a vitamin receptor binding moiety, a bivalent linker (L), and a drug. The vitamin receptor binding moiety includes vitamins, and vitamin receptor binding analogs and derivatives thereof, and the drug includes analogs and derivatives thereof. The vitamin receptor binding moiety is covalently linked to the bivalent linker, and the drug, or the analog or the derivative thereof, is covalently linked to the bivalent linker, wherein the bivalent linker (L) includes components such as spacer linkers, releasable linkers, and heteroatom linkers, and combinations thereof. Methods and pharmaceutical compositions for eliminating pathogenic cell populations using the drug delivery conjugate are also described.
    Type: Grant
    Filed: January 27, 2004
    Date of Patent: October 13, 2009
    Assignee: Endocyte, Inc.
    Inventors: Iontcho R. Vlahov, Christopher P. Leamon, Matthew A. Parker, Stephen J. Howard, Hari Krishna Santhapuram, Apparao Satyam, Joseph Anand Reddy
  • Publication number: 20080228181
    Abstract: Methods are disclosed for delivering energy to a body of a human or animal during a treatment procedure using an electrosurgical generator, a pre-set overall procedure time being defined for the treatment procedure, a ramp time being defined for a parameter to reach a pre-set threshold during the treatment procedure, the method comprising: measuring the parameter over time; and if the parameter has not substantially reached the pre-set threshold by the ramp time, setting a procedure extension time responsive to the time difference between the ramp time and the time at which the pre-set threshold was reached, and extending the overall procedure time by the procedure extension time.
    Type: Application
    Filed: February 25, 2008
    Publication date: September 18, 2008
    Applicant: Baylis Medical Company
    Inventors: Neil GODARA, Taylor Hillier, Matthew Parker, Hua Xin Lo, Jason Woo
  • Publication number: 20070031334
    Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The invention provides a compound of the formula for use in such methods. In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid of the formula H2NCHRCOOH, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.
    Type: Application
    Filed: October 11, 2006
    Publication date: February 8, 2007
    Inventors: Christopher Leamon, Matthew Parker
  • Patent number: 7128893
    Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The invention provides a compound of the formula for use in such methods. In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.
    Type: Grant
    Filed: May 6, 2003
    Date of Patent: October 31, 2006
    Assignee: Endocyte, Inc.
    Inventors: Christopher P. Leamon, Matthew A. Parker
  • Publication number: 20050218649
    Abstract: A shield designed to be installed in exterior frame walls of buildings for the penetration of flexible tubing, cabling, or wiring. Comprised of a round, rectangular or square sleeve attached to mounting plate(s) or angle(s). The mounting plates or angles have holes to allow for the attachment of the shield to the framing of an exterior frame wall. The mounting plates or angles are attached to the sleeve at an angle sufficient to prevent the kinking of flexible tubing, cabling, or wiring.
    Type: Application
    Filed: April 2, 2004
    Publication date: October 6, 2005
    Inventor: Matthew Parker
  • Publication number: 20050002942
    Abstract: The invention describes a vitamin receptor binding drug delivery conjugate, and preparations therefor. The drug delivery conjugate consists of a vitamin receptor binding moiety, a bivalent linker (L), and a drug. The vitamin receptor binding moiety includes vitamins, and vitamin receptor binding analogs and derivatives thereof, and the drug includes analogs and derivatives thereof. The vitamin receptor binding moiety is covalently linked to the bivalent linker, and the drug, or the analog or the derivative thereof, is covalently linked to the bivalent linker, wherein the bivalent linker (L) includes components such as spacer linkers, releasable linkers, and heteroatom linkers, and combinations thereof. Methods and pharmaceutical compositions for eliminating pathogenic cell populations using the drug delivery conjugate are also described.
    Type: Application
    Filed: January 27, 2004
    Publication date: January 6, 2005
    Inventors: Iontcho Vlahov, Christopher Leamon, Matthew Parker, Stephen Howard, Hari Santhapuram, Apparao Satyam, Joseph Reddy
  • Publication number: 20040260284
    Abstract: A pedicle screw provides for elimination of splaying forces caused by an internal closure member. A locking member dovetails with longitudinal channels in wall sections of the receiver, locking the wall sections together and preventing the splaying. The closure member when disposed within a bore of the receiver tightens the locking member onto an elongated member, preventing removal of the locking member and the elongated member from the receiver. The locking member and the closure member may be permanently rotatably inter-engaged for ease of insertion and removal.
    Type: Application
    Filed: June 23, 2003
    Publication date: December 23, 2004
    Inventor: Matthew Parker
  • Patent number: 6819109
    Abstract: A wand-type magnetic metal detector has a telescoping wand which shortens the wand sufficiently for the detector to be comfortably carried in a holster carried on the user's body. The user's hands are thereby freed for other tasks than carrying the detector.
    Type: Grant
    Filed: January 23, 2003
    Date of Patent: November 16, 2004
    Assignee: Schonstedt Instrument Company
    Inventors: Kenneth George Sowers, Donald Dale Sien, Thomas Matthew Parker
  • Publication number: 20040145369
    Abstract: A wand-type magnetic metal detector has a telescoping wand which shortens the wand sufficiently for the detector to be comfortably carried in a holster carried on the user's body. The user's hands are thereby freed for other tasks than carrying the detector.
    Type: Application
    Filed: January 23, 2003
    Publication date: July 29, 2004
    Applicant: Schonstedt Instruments Co.
    Inventors: Kenneth George Sowers, Donald Dale Sien, Thomas Matthew Parker
  • Publication number: 20040033195
    Abstract: The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent.
    Type: Application
    Filed: May 6, 2003
    Publication date: February 19, 2004
    Inventors: Christopher P. Leamon, Matthew A. Parker
  • Publication number: 20020184052
    Abstract: A method for a providing an elective organization that provides premium health services for people choosing to become a member of the organization. The method comprises (a) associating a plurality of doctors in various locations with an organization, the associated doctors being selected by the organization based on each doctor's respective credentials; and (b) charging a membership fee to allow a plurality of members to belong to the organization, the members being permitted to seek any number of visits with any of the associated doctors in any of the various locations, herein the organization does not provide health insurance, but provides additional medical care regardless of any health insurance a member may already possess.
    Type: Application
    Filed: June 5, 2001
    Publication date: December 5, 2002
    Inventor: Matthew A. Parker