Patents by Inventor Matthew A. Schiefer
Matthew A. Schiefer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230310844Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: ApplicationFiled: June 8, 2023Publication date: October 5, 2023Inventors: Dustin J. Tyler, Daniel Tan, Matthew Schiefer
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Patent number: 11672971Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: GrantFiled: November 18, 2020Date of Patent: June 13, 2023Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Dustin J. Tyler, Daniel Tan, Matthew Schiefer
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Patent number: 11612741Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: GrantFiled: August 28, 2020Date of Patent: March 28, 2023Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Dustin Tyler, Daniel Tan, Matthew Schiefer, Ronald J. Triolo
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Patent number: 11446483Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: GrantFiled: July 1, 2020Date of Patent: September 20, 2022Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Dustin Tyler, Daniel Tan, Matthew Schiefer
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Patent number: 10960203Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: GrantFiled: December 16, 2014Date of Patent: March 30, 2021Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Dustin Tyler, Daniel Tan, Matthew Schiefer
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Publication number: 20210069497Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: ApplicationFiled: November 18, 2020Publication date: March 11, 2021Inventors: Dustin J. Tyler, Daniel Tan, Matthew Schiefer
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Publication number: 20200391025Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: ApplicationFiled: August 28, 2020Publication date: December 17, 2020Inventors: Dustin Tyler, Daniel Tan, Matthew Schiefer
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Publication number: 20200330751Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: ApplicationFiled: July 1, 2020Publication date: October 22, 2020Inventors: Dustin Tyler, Daniel Tan, Matthew Schiefer
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Patent number: 10758728Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: GrantFiled: October 31, 2018Date of Patent: September 1, 2020Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Dustin Tyler, Daniel Tan, Matthew Schiefer
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Publication number: 20190060648Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: ApplicationFiled: October 31, 2018Publication date: February 28, 2019Inventors: Dustin Tyler, Daniel Tan, Matthew Schiefer
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Publication number: 20170246456Abstract: One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.Type: ApplicationFiled: December 16, 2014Publication date: August 31, 2017Inventors: Dustin Tyler, Daniel Tan, Matthew Schiefer
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Patent number: 9603538Abstract: An implantable cuff includes an elastic collar, at least one conductive segment disposed on or within the elastic collar, and at least one conductor in electrical communication with the at least one conductive segment. The elastic collar defines an internal opening configured to receive an internal body tissue. At least a portion of the elastic collar includes a stiffening region having a stiffness greater than a second region of the elastic collar. The at least one conductor is configured to operably mate with an apparatus capable of delivering electrical stimulation to, and/or recording an electrical activity of, the internal body tissue.Type: GrantFiled: June 17, 2013Date of Patent: March 28, 2017Assignee: Case Western Reserve UniversityInventors: Lee Fisher, Matthew Stone, Dustin J. Tyler, Daniel Tan, Matthew Schiefer, Natalie Brill, Michael Miller, Ronald Triolo
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Patent number: 9421366Abstract: The present invention generally relates to patterned intensity modulation of neural tissue. Certain embodiments provide a method of treating medical conditions by providing an electrode and modulating stimulation parameters delivered by the electrode. The stimulation parameters that are modulated relate to stimulation intensity and are varied according to a stimulation input parameter or time. The stimulation input parameter can be a choice of an individual waveform (i.e. ? or psi), which may be varied for each pulse.Type: GrantFiled: December 16, 2013Date of Patent: August 23, 2016Assignee: Case Western Reserve UniversityInventors: Dustin Tyler, Daniel Tan, Matthew Schiefer
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Publication number: 20150328465Abstract: The present invention generally relates to patterned intensity modulation of neural tissue. Certain embodiments provide a method of treating medical conditions by providing an electrode and modulating stimulation parameters delivered by the electrode. The stimulation parameters that are modulated relate to stimulation intensity and are varied according to a stimulation input parameter or time. The stimulation input parameter can be a choice of an individual waveform (i.e. ? or psi), which may be varied for each pulse.Type: ApplicationFiled: December 16, 2013Publication date: November 19, 2015Inventors: Dustin Tyler, Daniel Tan, Matthew Schiefer
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Publication number: 20150174396Abstract: An implantable cuff includes an elastic collar, at least one conductive segment disposed on or within the elastic collar, and at least one conductor in electrical communication with the at least one conductive segment. The elastic collar defines an internal opening configured to receive an internal body tissue. At least a portion of the elastic collar includes a stiffening region having a stiffness greater than a second region of the elastic collar. The at least one conductor is configured to operably mate with an apparatus capable of delivering electrical stimulation to, and/or recording an electrical activity of, the internal body tissue.Type: ApplicationFiled: June 17, 2013Publication date: June 25, 2015Inventors: Lee Fisher, Matthew Stone, Dustin J. Tyler, Daniel Tan, Matthew Schiefer, Natalie Brill, Michael Miller, Ronald Triolo
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Patent number: 8892211Abstract: A method for electrically stimulating a retina of an eye to induce visual perception includes placing an electrode adjacent a retinal ganglion cell (RGC) layer and selectively applying a biphasic asymmetrical waveform (BAW) to a portion of the axon. The BAW includes a pre-pulse phase and a stimulation-pulse phase. The pre-pulse phase has a first polarity, a first amplitude, and a first duration. The first amplitude and the first duration together define a pre-pulse charge having a first magnitude. The stimulation-pulse phase has a second polarity opposite the first polarity, a second amplitude, and a second duration less than the first duration. The second amplitude and the second duration together define a stimulation charge having a second magnitude. Application of the pre-pulse phase and the stimulation-pulse phase effects a change in excitability of the at least one ganglion cell and induces visual perception, respectively.Type: GrantFiled: May 27, 2010Date of Patent: November 18, 2014Assignee: Case Western Reserve UniversityInventors: Warren M. Grill, Matthew A. Schiefer
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Publication number: 20100305659Abstract: A method for electrically stimulating a retina of an eye to induce visual perception includes placing an electrode adjacent a retinal ganglion cell (RGC) layer and selectively applying a biphasic asymmetrical waveform (BAW) to a portion of the axon. The BAW includes a pre-pulse phase and a stimulation-pulse phase. The pre-pulse phase has a first polarity, a first amplitude, and a first duration. The first amplitude and the first duration together define a pre-pulse charge having a first magnitude. The stimulation-pulse phase has a second polarity opposite the first polarity, a second amplitude, and a second duration less than the first duration. The second amplitude and the second duration together define a stimulation charge having a second magnitude. Application of the pre-pulse phase and the stimulation-pulse phase effects a change in excitability of the at least one ganglion cell and induces visual perception, respectively.Type: ApplicationFiled: May 27, 2010Publication date: December 2, 2010Inventors: WARREN M. GRILL, Matthew A. Schiefer
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Publication number: 20070244523Abstract: A method for selective electrical stimulation of a retina for application in a visual neuralprosthesis. The method includes application of an asymmetrical, charge-balance biphasic waveform to increase the receptivity of selected cells to a subsequent stimulus, and then electrically stimulating to those selected cells to induce either a punctuate phosphene (perceived spot of light in the visual field) or a streak phosphene (streak of light in the visual field). A waveform having a sub-threshold anodic pulse followed by a supra-threshold cathodic pulse induces the punctuate phosphene, and a sub-threshold cathodic pulse followed by a supra-threshold anodic pulse induces the streak phosphene.Type: ApplicationFiled: April 13, 2007Publication date: October 18, 2007Applicant: Case Western Reserve UniversityInventors: Warren Grill, Matthew Schiefer