Abstract: A frame assembly for supporting a flat article. In one aspect, the frame assembly may include a stack including a transparent window panel and a frame. The frame may include a floor structure for supporting the stack and an outer annular wall coupled to and surrounding the floor structure, the outer annular wall including a plurality of corners, an outer surface defining a periphery of the frame, an inner surface defining a display cavity, and a front edge that defines a display opening configured to allow the stack to pass therethrough into the display cavity. The outer annular wall may have a non-uniform thickness. The corner portions may have lower and upper portions, with the lower portions having a greater thickness than the lower portions.

Abstract: A missile for a hydraulic fracturing system can include a high-pressure (HP) missile manifold having a plurality of HP input channels, a HP output channel, and a main HP channel disposed between the plurality of HP input channels and the HP output channel, where each of the plurality of HP input channels is configured to couple to and receive a fracturing fluid from a pump truck, where the HP output channel is configured to couple to and send the fracturing fluid to a main manifold, and where the main HP channel has a widening section along its length that separates a first HP portion of the main HP channel having a first HP diameter and a second HP portion of the main HP channel having a second HP diameter.

Abstract: A decorative moulding assembly for a wall or ceiling in an interior space. The decorative moulding assembly may include a first moulding piece and a second moulding piece each having an ornamental front surface, a rear surface, and a channel in the rear surface and a connector for connecting the first and second moulding pieces together. The connector may include a first portion that nests within the channel of the first moulding piece and a second portion that nests within the channel of the second moulding piece. The first portion of the connector may include a U-shaped body having first and second legs that deflect inwardly towards one another as the first portion of the connector is being inserted into the first channel of the first moulding piece.

Abstract: The present disclosure provides compositions including recombinant nucleic acid constructs, vectors, and host cells, and methods of their use for reducing reverse packaging of cap and/or rep DMA sequences in the production of recombinant adeno-associated vims (rAAV). Also provided are pharmaceutical compositions comprising an rAAV produced from a composition or method of the invention and a pharmaceutically acceptable carrier or excipient. These pharmaceutical compositions may be useful in gene therapy for the prevention or treatment of a disease, condition, or disorder in a subject.

Abstract: A doped or undoped silicon carbide film can be deposited using a remote plasma chemical vapor deposition (CVD) technique. One or more silicon-containing precursors are provided to a reaction chamber. Radical species, such as hydrogen radical species, are provided in a substantially low energy state or ground state and interact with the one or more silicon-containing precursors to deposit the silicon carbide film. A co-reactant may be flowed with the one or more silicon-containing precursors, where the co-reactant can be a depositing additive or a non-depositing additive to increase step coverage of the silicon carbide film.

Abstract: A frame apparatus for displaying an article. The frame apparatus includes a support structure having a frame and a backer panel. A plurality of slots are formed into the backer panel that include a first slot that is elongated along a first axis that is parallel to top and bottom edges of the support structure and a second slot that is elongated along a second axis that is parallel to lateral edges of the support structure. The frame apparatus may include a hanging element for hanging the support structure from a support surface such as a wall. The hanging element may be configured to be slidably coupled to the support structure such that the hanging element can slide back and forth within one of the slots while remaining coupled to the support structure. This structure enables the frame apparatus to move side-to-side along the support surface while hanging therefrom.

Abstract: A computing system identifies broadcast video for a plurality of games in a first league. The broadcast video includes a plurality of video frames. The computing system generates tracking data for each game from the broadcast video of a corresponding game. The computing system enriches the tracking data. The enriching includes merging play-by-play data for the game with the tracking data of the corresponding game. The computing system generates padded tracking data based on the tracking data. The computing system projects player performance in a second league for each player based on the tracking data and the padded tracking data.

Abstract: A computer implemented method of reducing data elements in a data file includes: receiving a data file including one or more primary data elements; storing the data file in a memory coupled to the processor; generating, from at least one of the one or more primary data elements, a plurality of supplemental data elements; determining whether any of the plurality of supplemental data elements and any of the primary data elements offset each other; and upon determining that at least one of the plurality of supplemental data elements and at least one of the primary data elements offset each other, deleting, from the data file, at least one of the offset supplemental data elements or primary data elements.

Abstract: An ingress-barrier assembly for use with pressure-operated downhole equipment can be used to limit hydraulic fluid flow in a wellbore environment for completions and operations through the life of a well. An assembly can comprise a first port to communicate hydraulic fluid with a first fluid conveyance line. The assembly can include a second port to communicate hydraulic fluid with a second fluid conveyance line. The assembly can further include a first-end stop, a second-end stop, and a moveable seal. The moveable seal can move within a bore of the assembly between the first-end stop and the second-end stop to communicate pressure between the first port and the second port.

Abstract: Aircraft information systems, aircraft that include the aircraft information systems, methods of utilizing the aircraft information systems, and methods of configuring the aircraft information systems are disclosed herein. The aircraft information systems include a fixed computing device configured to be fixedly installed within an aircraft. The fixed computing device is programmed to provide a cabin function interface that provides cabin functionality for a cabin attendant of the aircraft and also to provide a mechanic function interface that provides mechanic functionality for a mechanic for the aircraft. The aircraft include a fuselage, at least one wing, at least one engine, and the aircraft information systems.

Abstract: A method includes receiving a first navigation path risk request that includes first navigation path information associated with a first navigation path for a first unmanned vehicle through a first environment. The method also includes selecting a first risk model from a plurality of risk models based on the first navigation path information. The method also includes obtaining first data used as one or more inputs to run the first risk model from one or more data sources. The method also includes operating the first risk model with the first data to output a first risk score. The method also includes providing a first navigation path risk response in response to the first navigation path risk request that includes the first risk score that is associated with at least a portion of the first navigation path.

Abstract: A system for fracturing multiple wellbores on a multi-well pad can include a missile that receives high-pressure fracturing fluid from a plurality of pump truck. The system can also include a main manifold that receives the high-pressure fracturing fluid from the missile, where the main manifold includes multiple valves and multiple output channels, where each of the valves are operated between an open position and a closed position. The system can further include multiple wellbores including a first wellbore, a second wellbore, and a third wellbore, where the wellbores are connected to the output channels of the main manifold. The valves of the main manifold can be operated to enable simultaneous flow of the high-pressure fracturing fluid to the first wellbore, the second wellbore, and the third wellbore so that the first wellbore, the second wellbore, and the third wellbore are fractured simultaneously.

Abstract: This present disclosure provides recombinant adeno-associated virus (rAAV) and methods of their use in gene therapy for treating propionic acidemia (PA). Also provided are pharmaceutical compositions comprising a rAAV of the invention and a pharmaceutically acceptable carrier or excipient. These pharmaceutical compositions may be useful in gene therapy for the treatment of PA caused by a mutation in propionyl-CoA carboxylase ?-subunit (PCCA) or a mutation in propionyl-CoA carboxylase ?-subunit (PCCB).

Abstract: A wall hanging system by which a wall décor item such as a ledge, a frame, a mantel, or the like may be mounted to and hung from a wall. The wall hanging system may include the wall décor item having a rear surface and first and second mounting channels in the rear surface. The wall hanging system may also include first and second mounting brackets that are configured to be mounted to the wall. At least one of the first and second mounting brackets may have an elongated aperture through which a fastener extends for mounting that mounting bracket to the wall. As such, the mounting bracket with the elongated aperture is able to slide side-to-side along the wall while being mounted to the wall in order to properly align the first and second mounting brackets with the first and second mounting channels of the wall décor item.

Abstract: A method and system for calibrating fluorescence data in a multimodality image acquired from a vessel imaged by an imaging catheter. A fluorescence signal acquired by a first modality is calibrated by applying a first calibration factor based on a lumen distance and/or radiation angle from the catheter to the vessel wall. If a parameter of the calibrated fluorescence signal is different from a predetermined condition, a user is prompted to manually select a lumen boundary and/or a region of interest (ROI) on the image of the vessel. An optical attenuation property of the selected boundary and/or ROI is calculated based on backscattered radiation collected by a second modality, and the fluorescence signal is further calibrated by applying a second calibration factor based on the optical attenuation property.

Abstract: This disclosure relates to the once weekly dosing regimen of a dual GLP-1R and GCGR agonist, formulations, and methods of using the same for treatment of chronic weight management, obesity and/or blood glucose control, including but not limited to dual agonist peptide product of SEQ ID NO. 1.

Abstract: A frame assembly for supporting a flat article. In one aspect, the frame assembly may include a stack including a transparent window panel and a frame. The frame may include a floor structure for supporting the stack and an outer annular wall coupled to and surrounding the floor structure, the outer annular wall including a plurality of corners, an outer surface defining a periphery of the frame, an inner surface defining a display cavity, and a front edge that defines a display opening configured to allow the stack to pass therethrough into the display cavity. The inner surface of the outer annular wall may include a plurality of recessed regions, each of the recessed regions encompassing one of the corners of the outer annular wall.

Abstract: A railing system having a number of spaced apart support bases and a railing is provided. The railing includes a number of vertically extending stanchions connected to the support bases and a number of horizontally extending members extending between the vertically extending stanchions. The railing is configured to be shifted relative to the support bases between a stored position and an erected position. The railing is automatically secured in the erected position when the railing is shifted from the stored position to the erected position.

Abstract: A frame apparatus for displaying an article. The frame apparatus includes a support structure having a frame and a backer panel. A plurality of slots are formed into the backer panel that include a first slot that is elongated along a first axis that is parallel to top and bottom edges of the support structure and a second slot that is elongated along a second axis that is parallel to lateral edges of the support structure. The frame apparatus also includes a hanging element for hanging the support structure from a support surface such as a wall. The hanging element is configured to be slidably coupled to the support structure such that the hanging element can slide back and forth within one of the slots while remaining coupled to the support structure. This structure enables the frame apparatus to move side-to-side along the support surface while hanging therefrom.

Abstract: A gripping attachment (10) is disclosed which facilitates the handling of a medication bottle (12). The medication bottle includes a container (14) having a cylindrical wall (16) extending parallel to a longitudinal axis. The container is closed at one end by a base wall (18) and has an opposed open end. The container receives a cap (20) on the open end to enclose the container. The gripping attachment comprises a sleeve portion (22) having a sleeve wall (24) defining an internal, cylindrical surface configured to removably attach to the container wall. The gripping attachment further comprises a leverage component connected to the sleeve portion to facilitate gripping the sleeve portion.